Harvoniand/or alternativesChemical Ingredient: Ledipasvir/Sofosbuvir
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
- Manufactured by Gilead Sciences
- Product of Canada • Shipped from Canada
- Prescription Required
- Manufactured by Mylan Laboratories
- Product of India • Shipped from India
- Prescription Required
Harvoni Helps Treat the Following Conditions:
Hepatitis C is a liver disease caused by a bloodborne virus. Infection usually occurs through unsafe injection practices, or via the transfusion of contaminated blood and blood products. The virus can cause acute and chronic forms of the disease.
Acute hepatitis C does not often have symptoms, and up to 45% of infected people recover without treatment. The rest can go on to develop chronic hepatitis C. Antiviral therapy can treat 95% of these cases, although some patients may develop serious complications such as liver cancer and cirrhosis.
Harvoni Active Ingredients
Harvoni is a combination medication which contains two active ingredients: ledipasvir and sofosbuvir. Harvoni helps to reduce the amount of hepatitis C virus in the body, which in turn assists the immune system in fighting the infection more effectively.
Harvoni in the News
Harvoni Cures 97% of Hepatitis C Patients in Real-world Study
97% of hepatitis C patients who treated with the drug Harvoni were cured of the virus, according to a new real-world study.
The results are similar to those of earlier clinical trials. Researchers reviewed data from 311 patients who completed at least eight weeks of treatment with Harvoni. Patients were then tested to determine their response to the treatment.
Harvoni is manufactured by pharmaceutical company Gilead and contains two active ingredients: ledipasvir and sofosbuvir.
Harvoni General Drug Information
Harvoni is prescribed to patients with chronic hepatitis C, a viral infection of the liver. Chronic hepatitis C is a serious condition which can lead to complications like cirrhosis and liver cancer.
Harvoni is a combination medication which helps the immune system fight the hepatitis C virus, allowing the liver to recover. Harvoni is sometimes used with other antiviral drugs (e.g. ribavirin).
It is not known whether treatment with Harvoni can prevent patients from passing the virus to others. Patients should not share needles. They should use latex condoms – and other reliable methods – to lower the risk of passing the virus on to others during sex.
While Harvoni is prescribed to treat hepatitis C, hepatitis B patients may experience the worsening of their condition. Before starting Harvoni treatment, patients need to inform their doctor if they have ever been diagnosed with hepatitis B.
Patients should also monitor for symptoms of worsening liver disease: persistent nausea and vomiting, loss of appetite, stomach pain, dark urine, and the yellowing of the eyes or skin.
The information on this page is not a replacement for a consultation with a physician qualified to treat this condition and prescribe medication. The information is supplied by a third party, independent from this website. It serves to raise awareness about this condition and point out basic information you should consider before buying Harvoni online.
The website cannot take responsibility for the reliability or medical efficacy of the information provided. As mentioned above, patients should seek medical attention to ensure effective and safe treatment.
Not all products are shipped by our contracted Canadian pharmacy. The source country, shipping country or drug manufacturer may vary depending on availability.
The website also works with dispensaries around the world. Products can be sourced from a number of countries. Patients should note that different items within an order can be shipped from different jurisdictions, depending on availability and cost at the time an order was placed.
How to Use Harvoni
Before sourcing Harvoni or its generic alternatives online, please read the medication guide provided by your doctor or pharmacist.
Harvoni should be taken as prescribed by a patient’s doctor. Most patients are directed to take one daily oral dose. This medication works best when taken at evenly-spaced intervals so the drug maintains constant levels in the body. To prevent forgetting, patients should take the drug at the same time each day.
Patients should inform their doctor if they vomit within five hours after taking Harvoni. They may be directed to take another dose.
It is important to continue taking Harvoni for the full length of the treatment course, even if symptoms have disappeared. Ending treatment early may cause the infection to return.
Antacids lower the absorption of ledipasvir, one of the active ingredients in Harvoni. Patients who need to take antacids should do so at least four hours before or four hours after taking Harvoni.
Other medications for indigestion, heartburn, and ulcers may prevent Harvoni from working. This is the case with both prescription drugs and over-the-counter medications (e.g. famotidine and omeprazole). Patients should ask their doctor or pharmacist how to use such medications safely.
Patients need to discuss the possibility of allergic reactions to Harvoni and its generic alternatives before starting treatment. Patients preparing for surgery or certain dental procedures should inform their doctor or dentist about all medicines, supplements, and herbal products they are taking.
If you shop for Harvoni online, note that you may encounter the drug under its generic names: ledipasvir and sofosbuvir.
It is vital to discuss the patient’s medical history, especially of kidney disease or liver problems like hepatitis B.
Patients preparing for surgery should inform their doctor or dentist about all medicines, supplements and herbal products they are taking.
Harvoni should only be used when clearly needed during pregnancy. Women should discuss the risks and benefits of treatment with their doctor.
Combination treatment featuring Harvoni and ribavirin must not be used during pregnancy – by the mother or her male partner – as it can harm an unborn baby. In cases when one of the sexual partners uses this combination, two reliable forms of birth control (e.g. condoms and birth control pills) must be used. This applies during the course of treatment and for six months afterwards. In the event of a suspected pregnancy, the treating physician must be alerted right away.
It is unknown whether Harvoni passes into breast milk. Breastfeeding while using Harvoni (in combination with ribavirin) is not recommended. Women should consult their doctor before breast feeding.
Harvoni Missed Dose
Patients who miss a dose of Harvoni should take it as soon as they remember. If this happens less than six hours until the next dose, patients should skip the missed dose and proceed as usual. Patients should not double their dose to catch up.
Drug interactions may change the way Harvoni and its generic alternatives work, and can increase the risk of side effects. Before starting treatment, patients need to discuss the full list of medications and supplements they are taking with their doctor. Patients should not change their dose or stop taking this medication unless their physician advises them to do so.
Some medications – like the heart drug amiodarone and hepatitis C medication simeprevir – may interact negatively with Harvoni.
Certain other medications can affect the removal of Harvoni from the body, affecting how it works. Examples include rifamycin antibiotics like rifampin (Rifadin) and rifabutin (Mycobutin), and HIV medications such as tipranavir and ritonavir (Norvir). The list also includes the herb St. John's wort and drugs used to treat seizures (e.g. carbamazepine, phenobarbital, phenytoin, and primidone).
Harvoni slows the removal of certain medications from the body, affecting how they work (e.g. the cholesterol drug rosuvastatin).
Patients should not take Harvoni with other products that contain sofosbuvir (e.g. Sovaldi).
This document does not contain a full list of all possible interactions. Please consult your physician before buying Harvoni or its generic alternatives online.
Harvoni Side Effects
Many patients are able to take Harvoni safely without serious side effects.
Common side effects include: tiredness, nausea, diarrhea, and difficulty sleeping. Patients should alert their doctor or pharmacist if any of these symptoms persist.
Serious allergic reactions to Harvoni are rare, yet patients should be aware of allergic symptoms such as rash, itching and swelling, severe dizziness and trouble breathing.
Harvoni should be stored in the original container, at room temperature. Keep away from light and moisture. Do not store in the bathroom. Keep away from children and pets.
Unwanted medication should be disposed of properly and should never be poured down drains or flushed down the toilet. Patients should consult a pharmacist or their local waste disposal company to find out more about safe disposal methods.
Harvoni Drug Information
Harvoni is a combination of ledipasvir and sofosbuvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. It is not known if this treatment can prevent you from passing the virus to others. Do not share needles, and practice "safer sex" (including the use of latex condoms) to lower the risk of passing the virus to others.
Although Harvoni helps many people with hepatitis C, it may cause people who also have another liver problem called hepatitis B to get worse. Before starting Harvoni, tell your doctor if you have ever had hepatitis B. Tell your doctor right away if you have new or worsening symptoms of liver disease, such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, dark urine or yellowing eyes/skin.
How to Use Harvoni
Read the Patient Information Leaflet if available from your pharmacist before you start taking ledipasvir/sofosbuvir and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Harvoni by mouth with or without food as directed by your doctor, usually once daily. Harvoni works best when the amount of drug in your body is kept at a constant level. Therefore, take Harvoni at evenly spaced intervals. To help you remember, take it at the same time each day. Tell your doctor if you vomit within 5 hours after taking Harvoni. You may need to take another dose. Continue to take ledipasvir/sofosbuvir for the full length of time prescribed, even if symptoms disappear after a short time. Stopping the medication too early may result in a return of the infection. Antacids lower the absorption of ledipasvir. If you are taking an antacid, take it at least 4 hours before or 4 hours after Harvoni. Other acid-lowering medications for indigestion, heartburn, or ulcers (such as prescription or over-the-counter medications including famotidine, omeprazole) may prevent ledipasvir from working. Ask your doctor or pharmacist how to use these medications safely.
Before taking ledipasvir/sofosbuvir, tell your doctor or pharmacist if you are allergic to either of the drugs; or if you have any other allergies. may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Harvoni, tell your doctor or pharmacist your medical history,kidney disease, other liver problems (such as hepatitis B), diabetes. If you have diabetes, your blood sugar may be lower with hepatitis C treatment. This can increase your risk of low blood sugar, so your doctor may adjust your diabetes treatment plan. Tell your doctor right away if you have symptoms of low blood sugar such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, Harvoni should be used only when clearly needed. Discuss the risks and benefits with your doctor. Ledipasvir/sofosbuvir, in combination with ribavirin, must not be used during pregnancy by either the pregnant woman or her male partner. The combination may harm an unborn baby. Two reliable forms of birth control (such as condoms, birth control pills) must be used whenever at least one sexual partner is using these medicines together, and for six months after stopping treatment. If you or your partner becomes pregnant, or if you think you or your partner may be pregnant, tell your doctor right away. It is unknown if Harvoni passes into breast milk. Consult your doctor before breast-feeding. Breast-feeding is not recommended if Harvoni is used in combination with ribavirin.
If you miss a dose of Harvoni, take it as soon as you remember, unless it is less than 6 hours until the next dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.amiodarone, a certain other medication used to treat chronic hepatitis C (simeprevir). Harvoni can slow down the removal of other medications from your body, which may affect how they work. One example is rosuvastatin, among others. Other medications can affect the removal of ledipasvir/sofosbuvir from your body, which may affect how Harvoni works. Examples include rifamycins (such as rifampin, rifabutin), St. John's wort, tipranavir/ritonavir, drugs used to treat seizures (such as phenobarbital, carbamazepine, phenytoin, primidone), among others. Do not take Harvoni with other products that contain sofosbuvir.
Harvoni Side Effects
Tiredness, headache, nausea, diarrhea, or difficulty sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed Harvoni because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Harvoni do not have serious side effects. A very serious allergic reaction to Harvoni is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.List of Harvoni side effects
Store at room temperature away from light and moisture in the original container. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.