Buy Sovaldi Online

(Sofosbuvir)

The active ingredient in Sovaldi is sofosbuvir, a nucleotide analog inhibitor.

Sofosbuvir is a direct-acting antiviral that targets the hepatitis C virus polymerase enzyme. This enzyme is needed for the HCV infection to copy its genetic material and multiply in the body.

By blocking this polymerase, sofosbuvir stops the virus from making new copies of itself. This helps lower the amount of virus in the blood and supports a sustained virologic response. Many patients who complete the recommended course of treatment achieve a cure, meaning the virus is no longer detected in the blood.

Sovaldi is not used alone. It's combined with other drugs such as:

Ledipasvir/Sofosbuvir (Harvoni).

Velpatasvir/Sofosbuvir (Epclusa).

Daclatasvir + Sofosbuvir.

Ribavirin + Sofosbuvir (for certain genotypes).

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Sovaldi. However, the following is a synopsis of the general guidelines for the use of Sovaldi:

• Take Sovaldi exactly as prescribed by your healthcare provider.
• It is usually taken once daily.
• It may be taken with or without food.
• If using oral pellets, they may be mixed with soft food and swallowed without chewing.
• Sovaldi must be used in combination with other antiviral medicines as directed.
• Complete the full treatment regimen, even if you feel better.
• Treatment length depends on HCV genotype, cirrhosis status, and whether you are treatment-naïve or previously treated. Many HCV treatment regimens last 12 weeks, but this may vary.

If you miss a dose, take it as soon as you remember unless it is close to your next dose. Do not take two doses at the same time.

Some mild or common side effects of Sovaldi include:

• Tiredness.
• Headache.
• Nausea.
• Insomnia.
• Anemia when taken with ribavirin.
• Itching.

Some individuals may experience serious side effects while using Sovaldi. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of hepatitis B virus reactivation, such as yellowing of the skin or eyes.
• Severe allergic reaction.
• Slow heart rate when taken with amiodarone.
• Severe liver problems.

These are not all of the possible side effects of Sovaldi. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Sovaldi, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Hepatitis B virus coinfection.
• Cirrhosis or liver disease.
• A history of liver transplant.
• Hepatocellular carcinoma.
• Kidney problems.
• If you are pregnant or breastfeeding.
• Patients should be tested for the hepatitis B virus before starting treatment. Reactivation of hepatitis B has been reported in patients treated for chronic HCV.
• When used with ribavirin or peginterferon alfa, additional warnings apply, including the risk of anemia and birth defects.

Boxed Warning

Sovaldi carries a boxed warning for the risk of hepatitis B virus reactivation in patients coinfected with HCV and hepatitis B virus.

There are no specific contraindications listed for sofosbuvir alone. However, when used with ribavirin or pegylated interferon, additional contraindications may apply, including pregnancy with ribavirin.

Sovaldi begins working soon after starting treatment. Viral levels often decrease rapidly. Most treatment regimens last several weeks, commonly 12 weeks, depending on genotype and medical history.

When Sovaldi is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Amiodarone, which may cause a serious slow heart rate when used together.
• Carbamazepine, phenytoin, phenobarbital, oxcarbazepine, rifampin, rifabutin, and rifapentine, which may reduce sofosbuvir levels and decrease effectiveness.
• Tipranavir or ritonavir, which may affect drug levels.
• St. John’s wort, which may reduce effectiveness.
• Warfarin, which may require monitoring.

Sovaldi is available as:

400 mg tablets.

Oral pellets.

The usual adult dose is 400 mg once daily as part of combination therapy. Pediatric dosing is based on age and body weight. Your healthcare provider will determine the correct dose and treatment duration.

It should be stored at room temperature, away from the reach of children or pets.

Sovaldi is manufactured by Gilead Sciences.

Yes, sofosbuvir is available in generic form.

Do not stop taking Sovaldi without medical advice. Stopping early may reduce the chance of achieving a cure. Always complete the full prescribed course of treatment.

Talk to your doctor if you are pregnant or planning to become pregnant. When Sovaldi is used with ribavirin, there is a risk of birth defects. Effective contraception is required during treatment and for a period after completion if ribavirin is included.

It is not known whether sofosbuvir passes into breast milk. Talk to your healthcare provider if you are breastfeeding. They will help determine the safest option for you and your baby.