Diabeta

(Glyburide)

Micronase helps lower blood sugar levels in people with type 2 diabetes. It contains glyburide, which is a sulfonylurea. It stimulates beta cells in the pancreas to release more insulin and also helps the body use insulin more effectively. The increased insulin helps move glucose from the blood into the body’s cells, reducing blood sugar levels, but it requires a functioning pancreas to work properly.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Micronase. However, the following is a synopsis of the general guidelines for the use of Micronase:

• Micronase is taken by mouth, usually once daily with breakfast or the first main meal of the day.
• Take the tablet exactly as prescribed and at the same time each day.
• Swallow the tablet whole with water.
• Do not skip meals after taking Micronase, as this increases the risk of low blood sugar.
• Your healthcare provider may adjust your dose based on blood glucose levels and treatment response.
• Blood sugar monitoring is important while taking Micronase.
• If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses at the same time to make up for a missed dose.

Some mild or common side effects of Micronase include:

• Symptoms of hypoglycemia (low blood sugar) such as shakiness, sweating, headache, or hunger.
• Weight gain.
• Heartburn or stomach upset.
• Nausea.
• Dizziness or blurred vision, especially when starting treatment.
• Muscle or joint pain.

Some individuals may experience serious side effects while using Micronase. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe hypoglycemia with confusion, loss of consciousness, or seizures.
• Allergic reactions such as skin rash, hives, itching, swelling, or trouble breathing.
• Liver problems and symptoms such as dark urine, pale stools, and jaundice (yellowing of the skin or eyes).
• Unusual bruising or bleeding.
• Signs of hemolytic anemia, particularly in people with glucose-6-phosphate dehydrogenase deficiency.

These are not all of the possible side effects of Micronase. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Micronase, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Type 1 diabetes or diabetic ketoacidosis.
• A history of severe hypoglycemia.
• Kidney disease or liver disease.
• Glucose-6-phosphate dehydrogenase deficiency.
• Heart disease or risk factors for cardiovascular disease.
• Hormonal conditions affecting blood sugar control.
• An allergy to sulfonylureas or sulfa-containing drugs.
• Elderly patients may be more sensitive to the effects of Micronase and may have an increased risk of low blood sugar. Alcohol use can also increase the risk of hypoglycemia and should be discussed with a healthcare provider.

Micronase should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or known hypersensitivity to glyburide or other sulfonylureas. It is also contraindicated in patients with severe kidney or liver impairment, where the risk of toxicity may be increased.

Micronase begins lowering blood glucose levels within hours of the first dose. Full effects on blood sugar control may be seen over several days to weeks as the dose is adjusted and lifestyle measures are followed consistently.

When Micronase is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Metformin, which may increase the blood sugar-lowering effects and hypoglycemia risk.
• Colesevelam can reduce the absorption of glyburide if taken at the same time.
• Ciprofloxacin may increase the risk of low blood sugar.
• Bosentan may reduce the effectiveness of glyburide.
• Diuretics may raise blood glucose levels and reduce Micronase's effectiveness.
• Supplements that affect blood sugar levels increase the risk of hypoglycemia or hyperglycemia.

Micronase tablets are available in different strengths. Your healthcare provider will prescribe the dose based on your blood glucose levels and treatment response.

Micronase should be stored at room temperature, away from the reach of children or pets.

Micronase is manufactured by pharmaceutical companies that produce branded and authorized formulations of glyburide products.

Yes. Micronase is available as a generic medication under the generic name glyburide.

Do not stop taking Micronase without first speaking to your healthcare provider. Stopping suddenly may cause high blood sugar levels. Your provider may adjust your dose or switch medications based on your diabetes management plan.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. Blood sugar control is very important during pregnancy. Your healthcare provider will determine whether Micronase or another diabetes treatment is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. Glyburide may pass into breast milk in small amounts. Your healthcare provider will help decide if Micronase is appropriate or if another treatment should be used.