Miralax

(Polyethylene Glycol 3350)

The active ingredient in Miralax is Polyethylene Glycol 3350 (PEG 3350). PEG 3350 belongs to a class of medications known as osmotic laxatives that draw water into your intestines, softening your stools and making them easier to pass. Occasional constipation is generally associated with dietary choices such as a low fiber intake. However, there can be many different causes behind your constipation and you should consult your doctor or pharmacist before using Miralax.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-approved product Labeling, Instructions for Use, and Medication Guide before using Miralax. However, the following is a synopsis of the general guidelines for the use of Miralax:

• Miralax should only be used for those 17 years and older. For those younger, a doctor or pharmacist should be consulted before use.
• Miralax is used once daily. To use, dissolve 17g of the laxative powder in 4 to 8 ounces of your preferred beverage (the temperature does not matter). This is equivalent to one sachet or the top of the white section of the cap if you are using the bottle. Ensure that the powder is fully dissolved and there are no clumps before drinking.
• Miralax should not be combined with any starch-based thickeners. If you have difficulties swallowing and require a thickener, consult your doctor or pharmacist.
• Do not take more than the daily max dose unless advised by your doctor to do so.
• Do not use for more than 7 days. If constipation persists beyond this time frame, consult your doctor or pharmacist.

The most common side effects of Miralax seen in clinical trials as compared to placebo include:

• Nausea
• Cramping
• Bloating
• Passing gas

Some individuals may experience serious side effects while using Miralax. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Symptoms of a severe allergic reaction such as swelling of the face/lips/tongue, difficulty breathing, severe and widespread rash, fainting, or heart palpitations
• Harsh side effects such as severe nausea, cramping or bloating

These are not all of the possible side effects of Miralax. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Miralax, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• A sudden change in bowel movements or habits for more than 2 weeks
• Rectal bleeding
• An inability to pass gas (could indicate a blockage)
• IBS or irritable bowel syndrome
• Constipation with nausea, vomiting, or stomach pain
• Chronic constipation that requires you to use a laxative for more than 1 week

Do not use Miralax if you have:

• An allergy or hypersensitivity to Polyethylene Glycol 3350
• Kidney disease

It is unlikely you will experience sudden urgency after taking Miralax as it does take some time to work. You can expect constipation relief within 1-3 days after using Miralax.

When Miralax is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid drug interactions. This includes:

• Stimulant laxatives such as bisacodyl, senna, sodium picosulfate, etc.
• Other stool softeners

Miralax is available in individual sachets or as a bulk loose powder in bottles of different sizes. The dose of Miralax per day is 17g.

Miralax should be stored at room temperature away from moisture, cold, and heat, and out of reach of children.

Miralax is manufactured by the pharmaceutical company Bayer.

Yes, there are generic versions available OTC of the brand name Miralax.

Generally, Miralax can be stopped once you have regular bowel movements. However, consult your doctor or pharmacist before starting, stopping, or changing medications while taking Miralax.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.