Omeprazole/Sodium Bicarbonate(Omeprazole/Sodium Bicarbonate)
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Omeprazole/Sodium Bicarbonate Drug Information
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Omeprazole/Sodium Bicarbonate Overview
Omeprazole/Sodium Bicarbonate is a combination of omeprazole and sodium bicarbonate. Omeprazole/Sodium Bicarbonate is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It is also used to prevent stomach bleeding in very ill patients. Omeprazole works by decreasing the amount of acid your stomach makes. It belongs to a class of drugs known as proton pump inhibitors (PPIs). Sodium bicarbonate is an antacid that reduces stomach acid and helps omeprazole to work better. Omeprazole/Sodium Bicarbonate relieves symptoms such as heartburn, difficulty swallowing, and cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. If you are self-treating with Omeprazole/Sodium Bicarbonate, over-the-counter omeprazole/sodium bicarbonate products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.
How to Use Omeprazole/Sodium Bicarbonate
Read the Medication Guide provided by your pharmacist before you start taking Omeprazole/Sodium Bicarbonate and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Omeprazole/Sodium Bicarbonate by mouth as directed by your doctor, usually once daily on an empty stomach, at least 1 hour before a meal. The powder form of Omeprazole/Sodium Bicarbonate may also be given through a tube into the stomach (nasogastric or gastric tube). If you are self-treating, follow all directions on the product package. Dosage and length of treatment are based on your medical condition and response to treatment. In children, the Dosage of Omeprazole/Sodium Bicarbonate is also based on weight. Do not increase your dose or take Omeprazole/Sodium Bicarbonate more often than directed. If you have any questions, ask your doctor or pharmacist. If you are taking the capsule, swallow it whole with a full glass of water (8 ounces or 240 milliliters). Do not use other liquids. Do not open the capsule or sprinkle the contents into food. If you are using the powder packet, empty the contents into a small cup with 1 to 2 tablespoons (15 to 30 milliliters) of water. Do not use any other liquids or foods. Stir well and drink the entire mixture right away. To make sure you take the entire dose, add more water to the cup and drink all of it. If you are giving the powder through a nasogastric or gastric tube, ask your health care professional for detailed instructions on how to properly mix and give it. For patients receiving continuous tube feedings, the tube feeding should be stopped for 3 hours before and 1 hour after giving Omeprazole/Sodium Bicarbonate. Do not substitute the capsules or the powder packets for each other, unless approved by your doctor, because they contain different amounts of sodium bicarbonate. Also, do not substitute one strength of the same dosage form for another strength (such as taking two 20-milligram capsules instead of one 40-milligram capsule). Doing so may give you too much sodium bicarbonate and increase your risk of side effects (such as swelling of the hands/feet). If you are also taking sucralfate, take Omeprazole/Sodium Bicarbonate at least 30 minutes before sucralfate. Use Omeprazole/Sodium Bicarbonate regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take Omeprazole/Sodium Bicarbonate for the prescribed length of treatment even if you are feeling better. If you are self-treating with the over-the-counter product, do not take it for more than 14 days unless directed by your doctor. Tell your doctor if your condition lasts or gets worse. If you are self-treating, tell your doctor if your heartburn lasts after 14 days or if you need to use Omeprazole/Sodium Bicarbonate more than once every 4 months. The risk of side effects goes up over time. Ask your doctor how long you should take Omeprazole/Sodium Bicarbonate. If you think you may have a serious medical problem, get medical help right away.
Omeprazole/Sodium Bicarbonate Precautions
Before taking omeprazole/sodium bicarbonate, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as esomeprazole, lansoprazole, pantoprazole); or if you have any other allergies. Omeprazole/Sodium Bicarbonate may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before taking Omeprazole/Sodium Bicarbonate, tell your doctor or pharmacist your medical history,conditions affected by the sodium in Omeprazole/Sodium Bicarbonate (such as congestive heart failure, high blood pressure, swelling/edema), kidney problems (such as Bartter's syndrome, kidney failure), liver disease (such as cirrhosis), low blood calcium or potassium levels, metabolic imbalance (such as acid-base balance problems), lupus. Omeprazole/Sodium Bicarbonate contains salt (sodium). Before taking Omeprazole/Sodium Bicarbonate, tell your doctor or pharmacist if you are on a low-salt diet. Some symptoms may actually be signs of a more serious condition.heartburn with lightheadedness/sweating/dizziness, chest/jaw/arm/shoulder pain (especially with shortness of breath, unusual sweating), unexplained weight loss. In addition, before you self-treat with Omeprazole/Sodium Bicarbonate,trouble/pain swallowing food, bloody vomit, vomit that looks like coffee grounds, bloody/black stools, heartburn for over 3 months, frequent chest pain, frequent wheezing (especially with heartburn), nausea/vomiting, stomach pain. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Proton pump inhibitors (such as omeprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor or pharmacist about ways to prevent bone loss/fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements. Older adults may be more sensitive to the side effects of Omeprazole/Sodium Bicarbonate, especially bone loss and fractures (see above), and C. difficile infection (see Side Effects section). Children may be more sensitive to the side effects of omeprazole, especially fever, cough, and infections of the nose/throat/airways. During pregnancy, Omeprazole/Sodium Bicarbonate should be used only when clearly needed. Discuss the risks and benefits with your doctor. Omeprazole/Sodium Bicarbonate passes into breast milk. The effects on a nursing infant are unknown. Consult your doctor before breast-feeding.
Omeprazole/Sodium Bicarbonate Misdose
If you miss a dose of Omeprazole/Sodium Bicarbonate, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Omeprazole/Sodium Bicarbonate Interactions
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.cilostazol, clopidogrel, mavacamten, memantine, methotrexate (especially high-dose treatment), rifampin, St John's wort. Some products need stomach acid so that the body can absorb them properly. Omeprazole/sodium bicarbonate decreases stomach acid, so it may change how well these products work. Some affected products include atazanavir, erlotinib, levoketoconazole, nelfinavir, pazopanib, rilpivirine, certain azole antifungals (itraconazole, ketoconazole, posaconazole), among others. Omeprazole is very similar to esomeprazole. Do not use any medications containing esomeprazole while using omeprazole. Omeprazole/Sodium Bicarbonate may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Omeprazole/Sodium Bicarbonate.
Omeprazole/Sodium Bicarbonate Side Effects
See also Precautions section. Headache or abdominal pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If your doctor has directed you to use Omeprazole/Sodium Bicarbonate, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Omeprazole/Sodium Bicarbonate do not have serious side effects. Tell your doctor right away if you have any serious side effects,swelling of the hands/feet, symptoms of a low magnesium blood level (such as muscle spasms, irregular heartbeat, seizures), sudden weight gain, signs of lupus (such as rash on nose and cheeks, new or worsening joint pain). When taken with sodium bicarbonate, large doses of calcium from your diet, medications, or supplements can rarely cause a serious problem called milk-alkali syndrome. Ask your doctor or pharmacist about using calcium products safely while you are using Omeprazole/Sodium Bicarbonate.dizziness, muscle aches/spasms, mental/mood changes (such as confusion, irritability, memory problems), vomiting, weakness. Omeprazole/Sodium Bicarbonate may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped.diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool. If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse. Rarely, proton pump inhibitors (such as omeprazole) have caused vitamin B-12 deficiency. The risk is increased if they are taken every day for a long time (3 years or longer). Tell your doctor right away if you develop symptoms of vitamin B-12 deficiency (such as unusual weakness, sore tongue, or numbness/tingling of the hands/feet). A very serious allergic reaction to Omeprazole/Sodium Bicarbonate is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, signs of kidney problems (such as change in the amount of urine). This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Omeprazole/Sodium Bicarbonate Storage
Store at room temperature away from light and moisture. Do not open the packets until ready to use. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Omeprazole/Sodium Bicarbonate when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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