Otezla

(Apremilast)

Otezla (apremilast) is indicated to treat adult patients with moderate to severe plaque psoriasis that are candidates for phototherapy or systemic therapy, active psoriatic arthritis (PsA), or oral ulcers associated with Behcet’s disease.

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Brand Versions

OtezlaPrescription Required

Strength
30mg
Country
Australia
Select Quantity

Otezla Starter PackPrescription Required

Strength
10/20/30mg
Country
Australia
Select Quantity
Titration pack consists of 4 x 10mg tabs, 4 x 20mg tabs, and 19 x 30mg tabs.

Marketed as Otezla Titration Pack in Australia

Generic Versions
What are generics?

ApremilastPrescription Required

Strength
10mg
Country
India
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Marketed as Aprezo in India

ApremilastPrescription Required

Strength
20mg
Country
India
Select Quantity

Marketed as Apraize in India

Also available from India
Strength
20mg
Country
India
Select Quantity

Marketed as Aprezo in India

ApremilastPrescription Required

Strength
30mg
Country
India
Select Quantity

Marketed as Aprezo in India

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Important information about Otezla

How does Otezla work?

The active ingredient in Otezla, apremilast, is a phosphodiesterase-4 (PDE-4) inhibitor. It works to slow down or stop certain conditions that happen because of an overactive immune system. In general, it works to lower inflammation in the body by increasing the level of cAMP (cyclic adenosine monophosphate), which is a messenger system in our bodies.

How do you use Otezla?

Follow all directions and drug information given by your doctor and read the Full Prescribing Information and FDA-approved product labeling, patient information, instructions for use, and Medication Guide before using Otezla.

Your medication will come with a starter guide and packet. Make sure you read it all and follow the instructions provided unless otherwise directed by your healthcare provider. You can decide if you would like to take Otezla with or without food. However, do not chew, break, or split the tablets; take them whole. If you have any mild symptoms, talk to your doctor, and they may lower your dosage.

If you miss a dose of Otezla, take the missed dose immediately after you remember. However, if it is closer to the time of your next dose, skip this dose and take your next dose at your normal time.

What are the side effects of Otezla?

The most common side effects of Otezla seen in clinical trials as compared to placebo include:

  • Diarrhea or severe diarrhea
  • Upper respiratory tract infection
  • Nausea
  • Tension headache
  • Weight loss
  • Back pain

Rarely, Otezla may cause some serious side effects, including:

  • Depression
  • This could include suicidal thoughts.
  • Monitor for signs of depression, especially worsening symptoms or general mood changes. Receive medical help when necessary.
  • Serious, life-threatening allergic reactions, including anaphylaxis.
  • Symptoms of anaphylaxis may include hives (raised red patches on your skin), swelling of your face, lips, tongue, or throat, and trouble breathing.
  • Seek immediate medical attention if you experience any symptoms of a severe allergic reaction.

These are not all of the possible adverse effects of Otezla. You should always seek medical advice from a healthcare professional for any questions or concerns about your medical condition or treatment. You should also read all the patient and drug information, including your Medication Guide that comes with Otezla. You can report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What are the warnings or precautions for Otezla?

Before starting Otezla, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Kidney disease
  • A pregnancy, plan to become pregnant or are breastfeeding
  • Mood disorders, such as depression.
  • A hypersensitivity or have had an allergic reaction to any ingredient in Otezla.

Are there any contraindications with Otezla?

You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Known hypersensitivity to apremilast or to any of the excipients in the

formulation

How long does it take Otezla to work?

Otezla (apremilast), a medication used to treat psoriasis, psoriatic arthritis, and Behçet’s disease, can take several weeks to a few months to show noticeable improvements, depending on the condition being treated.

What interacts with Otezla?

When Otezla is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

Strong cytochrome P450 enzyme inducers (examples: phenobarbital, rifampin, carbamazepine, phenytoin, St. John’s wort). These may change the levels of Otezla in your body.

What doses of Otezla are available?

Otezla (apremilast) is available in the following doses:

10 mg tablets

20 mg tablets

30 mg tablets

How do I store Otezla?

Store Otezla below 30°C (86°F) out of the reach of children.

Which pharmaceutical company manufactures Otezla?

Otezla is manufactured by Amgen, inc.

Is there a generic version of Otezla?

Currently, there is no generic available for Otezla in the United States.

How do I stop taking Otezla?

To stop using Otezla, it's important to consult with your healthcare provider for a safe discontinuation plan. Stopping abruptly may cause a worsening of your symptoms.

Can Otezla be used if I am pregnant?

Talk to your healthcare provider if you become pregnant or plan on becoming pregnant while you're taking Otezla. Though unclear, there might be a risk of harm to unborn babies if the medication is taken during pregnancy.

Can Otezla be used if I am breast feeding?

It is unknown if this medication passes into breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Otezla from UniversalDrugstore™

What happens after I place my order for Otezla with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Otezla?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Otezla?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Otezla?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Otezla?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Otezla?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.