Pentasa
Pentasa is a brand-name anti-inflammatory agent used to treat active ulcerative colitis (UC), an inflammatory bowel disease. It helps relieve mild to moderate UC symptoms such as diarrhea, gut inflammation, and stomach pain. In adults, this drug can also be used to keep UC in remission (avoid flare-ups).
Pentasa is also used off-label as a treatment for Crohn’s disease.
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Pentasa Prescription Required
Marketed as Pentasa Sachet in United Kingdom
Pentasa Prescription Required
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Pentasa Prescription Required
Pentasa Prescription Required
Pentasa Prescription Required
Marketed as Salmiden in Turkey
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Important information about Pentasa
How does Pentasa work?
The active ingredient in Pentasa is mesalamine, which is an aminosalicylate. The precise mechanism of action of mesalamine is unknown. However, it seems to reduce gut inflammation, which helps alleviate UC symptoms inside the bowels.
How do you use Pentasa?
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-approved product Labeling, Instructions for Use, and Medication Guide before using Pentasa. However, the following is a synopsis of the general guidelines for the use of Pentasa:
- The outcomes of some medical tests may be impacted by this medication. Inform any medical professional you see about your use of mesalamine.
- To help avoid kidney stones, drink a lot of water.
- You can take Pentasa with or without food.
- Do not chew or crush the contents of the capsule; instead, swallow it whole. If you have problems swallowing the capsule, let your doctor know.
- You can open a Pentasa capsule and mix the medication into a spoonful of applesauce or yogurt if you are unable to swallow it whole. Without chewing, swallow the entire mixture at once. Don't put it away until later.
- If your ulcerative colitis symptoms worsen or do not go away, give your doctor a call.
- You may need frequent blood tests to check your blood cells or kidney function.
What are the side effects of Pentasa?
The most common side effects of Pentasa include:
- Nausea or vomiting.
- Stomach pain or abdominal pain.
- Indigestion or diarrhea.
- Loss of appetite.
- Weight loss.
- Bloody diarrhea.
- Dizziness.
- Flu or cold symptoms like sore throat.
- Back pain.
Some individuals may experience serious side effects while using Pentasa. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Worsening symptoms of ulcerative colitis.
- Blood in the urine, difficulty peeing, changes in urine volume, back or side pain, fever, chills, and kidney issues (including kidney stones).
- Liver issues include fatigue, black urine, worsening stomach pain, and yellowing of the skin or eyes (jaundice).
- Rashes, hives, skin rash, trouble breathing, chest pain, and swelling of the face, mouth, tongue, or throat are all signs of hypersensitivity or allergic reaction.
- Mesalamine can cause severe skin reactions, called Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP): blisters, hives, skin discoloration, and peeling; may or may not be accompanied by fever or body pains.
- Acute intolerance syndrome: cramping, abdominal pain, bloody diarrhea, fever, headache, fatigue, itching, and rash.
These are not all of the possible side effects of Pentasa. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Pentasa?
Before starting Pentasa, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- Kidney disease, kidney problems, or a kidney stone.
- Liver disease or other liver problems.
- An obstruction in your intestines or stomach (like pyloric stenosis).
- A skin disorder like eczema.
- Allergies to mesalamine, aspirin, sulfasalazine, or salicylates (including Disalcid, Doans Pills, Dolobid, Kaopectate, Nuprin Backache, Pepto-Bismol, Tricosal, Trilisate, and others) should prevent you from using Pentasa.
- Other medicines used for UC, like prednisone, can suppress the immune system.
- Mesalamine can make your skin more sensitive to light from the sun, sunlamps, and tanning beds. This is called photosensitivity. Avoid if possible.
Are there any contraindications with Pentasa?
- Allergy to aspirin or other salicylates.
- Hypersensitivity reactions, including myocarditis and pericarditis.
How long does it take Pentasa to work?
The symptoms of UC may not go away with mesalamine for a few weeks. After 6 or 8 weeks of treatment, patients taking various oral formulations of mesalamine reported improvements in their UC symptoms. Results may be seen as quickly as two weeks after starting a higher dose of mesalamine for certain patients. Because it may take a few weeks to notice any changes, don't give up and keep taking the prescription as directed by your doctor. Check in with your provider to see if mesalamine is assisting with your UC symptoms.
What interacts with Pentasa?
When Pentasa is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Azathioprine.
- Mercaptopurine or 6-mercaptopurine.
- NSAIDs, medications for pain and inflammation, such as ibuprofen or naproxen.
What doses of Pentasa are available?
For Treating Mild to Moderate Ulcerative Colitis (UC) or for Maintenance Treatment:
Pentasa (extended-release capsules): Adults usually take 1 gram (four 250-mg capsules or two 500-mg capsules) four times daily for up to eight weeks.
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.
How do I store Pentasa?
Store Pentasa at room temperature and out of reach of children.
Which pharmaceutical company manufactures Pentasa?
Takeda Pharmaceuticals America, Inc. is the manufacturing company of Pentasa.
Is there a generic version of Pentasa?
There are a few lower-cost generic versions of Pentasa available.
How do I stop taking Pentasa?
Your condition can deteriorate if you abruptly stop taking it. If you experience any discomfort while taking Pentasa, notify your physician or pharmacist right away. The majority of people benefit from this medication, but some people may experience unfavourable side effects.
Can Pentasa be used if I am pregnant?
If you are or intend to become pregnant, let your doctor know. The potential risks of mesalamine to a developing fetus are unknown. Premature birth or low birth weight are two consequences of untreated or uncontrolled ulcerative colitis during pregnancy. Any hazards to the unborn child may be outweighed by the advantages of treating ulcerative colitis.
Can Pentasa be used if I am breast feeding?
Breastfeeding while taking this medication might not be safe as the medication could pass through the breast milk. Enquire about any risks with your physician. If you observe diarrhea in your nursing infant, let your doctor know.
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What happens after I place my order for Pentasa with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Pentasa?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Pentasa?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Pentasa?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
How is my medication packaged to ensure privacy and safety?
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Does Universal Drugstore ship medications that require refrigeration or special handling?
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
What are the shipping costs, and does Universal Drugstore offer free delivery?
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Does Universal Drugstore accept Medicare or Medicaid for prescriptions?
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Can I use private health insurance to cover my prescription from Universal Drugstore?
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
How secure is my payment information when ordering from Universal Drugstore?
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Can I order a generic alternative to Pentasa?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Pentasa?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Does Universal Drugstore offer discounts or price matching?
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
How can I contact Universal Drugstore for additional support?
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
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