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Buy Synjardy Online
(Empagliflozin/Metformin Hydrochloride)

What is Synjardy?

What is Synjardy?

Synjardy is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Ultimately, it lowers blood sugar levels in people with type 2 diabetes. Also, it is used to lower the risk of dying from heart problems among people who also have heart disease, heart failure, or chronic kidney disease. It is important to note that this medication is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Order Synjardy online today and save!

Purchase Synjardy from Universal Drugstore today and save!

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  • 5/500mg
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  • 12.5/850mg
  • 12.5/1000mg

Synjardy brand

Synjardy 
5/500mg

Prescription Required
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Jardiance Met is manufactured by Boehringer Germany.
Prescription Required
Product of India

Product of India

Marketed as Jardiance Met in India.

Also available from New Zealand
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Prescription Required
Product of New Zealand

Product of New Zealand

Marketed as Jardiamet in New Zealand

Synjardy 
5/850mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Synjardy 
5/1000mg

Prescription Required
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Prescription Required
Product of New Zealand

Product of New Zealand

Marketed as Jardiamet in New Zealand.

Also available from Turkey
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Prescription Required
Product of Turkey

Product of Turkey

Marketed as Synjardy in Turkey

Synjardy 
12.5/500mg

Prescription Required
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Prescription Required
Product of New Zealand

Product of New Zealand

Marketed as Jardiamet in New Zealand.

Synjardy 
12.5/850mg

Prescription Required
Select Quantity
Prescription Required
Product of United Kingdom

Product of United Kingdom

Synjardy 
12.5/1000mg

Prescription Required
Select Quantity
Prescription Required
Product of India

Product of India

Marketed as Jardiance Met in India.

Also available from New Zealand
Select Quantity
Prescription Required
Product of New Zealand

Product of New Zealand

Marketed as Jardiamet in New Zealand

Empagliflozin/Metformin Hydrochloride (generic Synjardy)

What are generics?

Empagliflozin/Metformin Hydrochloride 
12.5/500mg

Prescription Required
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Prescription Required
Product of India

Product of India

Marketed as Gibtulio Met in India.

Empagliflozin/Metformin Hydrochloride 
12.5/1000mg

Prescription Required
Select Quantity
Prescription Required
Product of India

Product of India

Marketed as Gibtulio Met in India.

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Important information about Synjardy

The active ingredients in Synjardy are empagliflozin and metformin hydrochloride. Empagliflozin is considered a sodium-glucose co-transporter 2 or SGLT2 inhibitor, while metformin is a biguanide. Synjardy has several mechanisms of action to help keep blood glucose and sodium levels from getting too high in the body.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Synjardy. However, the following is a synopsis of the general guidelines for the use of Synjardy:

  • Take this medication orally with food exactly as directed by your physician.
  • Immediate-release (Synjardy) tablets can be used for people 10 years of age and older, but the extended-release (Synjardy XR) tablets are only for adults. Depending on which formulation you're using, dosing can be once or twice daily.
  • If you miss a dose, take it with food as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at its regular scheduled time. Do not take extra doses to make up for a missed dose.

The most common side effects of Synjardy include:

  • Low blood sugar. You are at a higher risk if you take Synjardy with insulin or a sulfonylurea.
  • Urinary tract infections.
  • Upper respiratory tract infection.
  • Vaginal yeast infection in females.
  • Genital fungal infections in males.
  • Joint pain.
  • Frequent urination.
  • Nausea.
  • Vomiting.
  • Diarrhea.
  • Excessive gas.
  • Belly discomfort.
  • Indigestion.
  • Lack of energy.
  • Headache.

Some individuals may experience serious side effects while using Synjardy. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Severe, life-threatening allergic reaction - hives, itching, rash, swelling, feeling lightheaded.
  • Diabetic ketoacidosis (DKA) - high ketone levels in the blood.
  • Lactic acidosis - buildup of lactic acid leading to muscle pain, trouble breathing, stomach pain, irregular heartbeats.
  • Kidney problems and dehydration.
  • Low blood sugar (hypoglycemia) - fast heartbeat, lightheadedness, lower dose of your other diabetes medicine to reduce your risk of hypoglycemia.
  • Necrotizing fasciitis (Fournier’s Gangrene).
  • Low vitamin B12 levels.
  • Serious genital infection.
  • Increased risk of amputations.

These are not all of the possible side effects of Synjardy. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Synjardy, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether any of the following apply:

  • Kidney problems.
  • Liver problems.
  • Heart problems (congestive heart failure, heart attack, heart disease).
  • Drink alcohol often or in large amounts.
  • Genital infection (penis or vagina).
  • Stroke.
  • Anemia.
  • Diabetic ketoacidosis.
  • A diet low in salt.
  • Having surgery.
  • High cholesterol.
  • History of pancreas problems.
  • Low blood pressure.
  • Polycystic ovary syndrome.
  • Problems urinating.
  • Type 1 diabetes.

Boxed Warning

  • Increaseed risk of lactic acidosis. If not treated properly, it can lead to other serious health problems, including organ failure, which can be life-threatening.

  • Renal Impairment, ESRD, or on dialysis.
  • Metabolic acidosis, including diabetic ketoacidosis.
  • History of previous serious allergic reaction/hypersensitivity reaction to empagliflozin or metformin.

Synjardy starts working in your body shortly after you take it. However, it may take several days or even 1 to 2 weeks before Synjardy has its full effect on lowering your blood sugar level.

When Synjardy is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Cationic drugs eliminated by renal tubular secretion.
  • Lithium.
  • Diuretics (water pills) that are used to reduce edema (fluid retention) and blood pressure.
  • Carbonic anhydrase inhibitor.
  • Other antidiabetic medications.

Synjardy and Synjardy XR are available in the following dosage forms and strengths:

  • 5 mg empagliflozin/500 mg metformin hydrochloride immediate release tablets.
  • 5 mg empagliflozin/1000 mg metformin hydrochloride immediate release tablets.
  • 12.5 mg empagliflozin/500 mg metformin hydrochloride immediate release tablets.
  • 12.5 mg empagliflozin/1000 mg metformin hydrochloride immediate release tablets.
  • 5 mg empagliflozin/1000 mg metformin extended-release oral tablets.
  • 10 mg empagliflozin/1000 mg metformin extended-release oral tablets.
  • 12.5 mg empagliflozin/1000 mg metformin extended-release oral tablets.
  • 25 mg empagliflozin/1000 mg metformin extended-release oral tablets.

Store this medication at room temperature and keep it out of reach of children.

Boehringer Ingelheim Pharmaceuticals is the company that manufactures Synjardy.

There are no lower-cost generics available for the brand-name Synjardy.

Do not stop or adjust your use of this medication without first consulting with your doctor.

Synjardy may cause harm to your unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

It is unknown if Synjardy passes into breast milk, but it is generally not recommended for use if you are breastfeeding.. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Synjardy from UniversalDrugstore™

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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Medical Disclaimer

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.