Tapazole

The active ingredient in Tapazole is methimazole. Methimazole works by reducing the production of thyroid hormone in the thyroid gland. When too much thyroid hormone (thyroxine and triiodothyronine) is circulating, symptoms of hyperthyroidism occur, such as a fast heartbeat, weight loss, anxiety, heat intolerance, and tremors. By blocking thyroid hormone formation, methimazole helps the body move toward a normal, euthyroid state.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Tapazole. However, the following is a synopsis of the general guidelines for the use of Tapazole:

• It may be taken with or without food.
• If you miss a dose, take the next dose at your usual time. Do not take extra tablets to make up for a missed dose.
• Routine blood tests are often required to check thyroid function and white blood cell levels.

Some mild or common side effects of Tapazole include:

• Skin rash.
• Nausea.
• Vomiting.
• Hair loss.
• Joint pain.
• Nausea or stomach upset.
• Loss of taste.
• Drowsiness.

Some individuals may experience serious side effects while using Tapazole. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Agranulocytosis, a severe drop in white blood cell count, may present as fever, sore throat, or infections.
• Aplastic anemia (very low red blood cells) or thrombocytopenia (low platelets).
• Hepatitis or liver problems, including jaundice or dark urine.
• Hypothyroidism from over-treatment, with symptoms such as weight gain or fatigue.
• Vasculitis (thickening of blood vessels).
• Severe allergic reaction, such as trouble breathing, swelling, or hives.

These are not all of the possible side effects of Tapazole. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Tapazole, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

Liver disease or a history of hepatitis.

Bone marrow issues or low white blood cell count.

A history of blood disorders, such as leukopenia.

Hypothyroidism or previous thyroid hormone problems.

Conditions affecting bleeding risk, such as hypoprothrombinemia.

Known hypersensitivity to methimazole or any component of the formulation.

Tapazole begins to reduce thyroid hormone levels within days, but noticeable improvement in symptoms may take 2–4 weeks.

When Tapazole is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

Anticoagulants, including warfarin, may have an increased effect when combined with Tapazole.

Theophylline, digoxin, or Beta-blockers such as propranolol may require a dose reduction once your thyroid levels normalize.

It is available in tablets containing 5mg or 10mg of methimazole.

It should be stored at room temperature, away from the reach of children or pets.

Tapazole is manufactured by King Pharmaceuticals.

Yes, it is available from many manufacturers of generic drugs.

Do not stop taking Tapazole without speaking to your healthcare provider. Stopping suddenly may worsen hyperthyroidism or trigger complications such as thyroid storm.

Methimazole may carry certain fetal risks, especially in early pregnancy. It is usually reserved for later stages of pregnancy.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Small amounts of methimazole may pass into breast milk, but studies show no significant effects on growing infants.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.