(Sumatriptan Succinate/Naproxen Sodium)
  • All Strengths

  • 85/500mg

Generic equivalents

What is a generic medication?

Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.

Sumatriptan Succinate/Naproxen Sodium 85/500mg
Prescription required. Manufactured by Lupin Pharmaceuticals Inc. Product of India. Shipped from India.

Treximet Drug Information

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You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.

  • Treximet Overview

    naproxen and sumatriptan. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound) in adults and in children 12 years or older. Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Naproxen is known as a nonsteroidal anti-inflammatory drug (NSAID). Treximet is used to relieve pain. Sumatriptan belongs to a class of drugs called triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain. Treximet does not prevent future migraines or lessen how often you get migraine attacks.

  • Treximet Warnings

    See also Side Effects and Precautions sections. Nonsteroidal anti-inflammatory drugs (including naproxen) may rarely increase the risk for a heart attack or stroke. This effect can happen at any time while taking Treximet but is more likely if you take it for a long time. The risk may be greater in older adults or if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). Do not take Treximet right before or after heart bypass surgery (CABG). Treximet may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning at any time while taking Treximet. Older adults may be at higher risk for this stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, slurred speech, sudden vision changes.

  • How to Use Treximet

    Read the Medication Guide provided by your pharmacist before you start using Treximet and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Treximet by mouth at the first sign of a migraine as directed by your doctor, with a full glass of water (8 ounces/240 milliliters). Do not lie down for at least 10 minutes after taking Treximet. To prevent stomach upset, take Treximet with food, milk, or an antacid. Do not break, crush, or chew the tablet. The Dosage of Treximet is based on your medical condition, age, and response to treatment. If there is no improvement in your symptoms, do not take more doses of Treximet before talking to your doctor. If your symptoms are only partly relieved, or if your headache comes back, you may take another dose at least two hours after the first dose. Do not take more than 2 doses in a 24-hour period. If you have a higher risk for heart problems (see Precautions), your doctor may perform a heart exam before you start taking Treximet. He/she may also direct you to take your first dose of Treximet in the office/clinic to monitor for serious side effects (such as chest pain). Talk to your doctor for details. If you are using drugs for migraine attacks on 10 or more days each month, the drugs may actually make your headaches worse (medication overuse headache). Do not use medications more often or for longer than directed. Tell your doctor if you need to use Treximet more often, or if the medication is not working as well, or if your headaches get worse.

  • Treximet Precautions

    Before taking Treximet, tell your doctor or pharmacist if you are allergic to naproxen or to sumatriptan; or to aspirin or other NSAIDs (such as ibuprofen, celecoxib); or if you have any other allergies. Treximet may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before taking Treximet, tell your doctor or pharmacist your medical history,asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), blood circulation problems (for example, in your legs, arms/hands, or stomach), blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps), certain types of headaches (hemiplegic or basilar migraine), heart problems (such as chest pain, irregular heartbeat, previous heart attack), liver disease, seizure, stroke or "mini-stroke" (transient ischemic attack), throat/stomach/intestinal problems (such as bleeding, heartburn, ulcers), swelling (edema, fluid retention). Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions,high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal (women), age more than 40 years (men). Kidney problems can sometimes occur with the use of NSAID medications, including naproxen. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine. Treximet may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information. Treximet contains salt (sodium). Before using Treximet, tell your doctor if you are limiting the amount of salt in your diet. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Treximet may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Older adults may be at greater risk for stomach/intestinal bleeding, increased blood pressure, kidney problems, heart attack, and stroke while using Treximet. Before using Treximet, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, Treximet should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery. These drugs pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

  • Treximet Misdose

    Not applicable. (See How to Use section.)

  • Treximet Interactions

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), cidofovir, corticosteroids (such as prednisone), "water pills" (diuretics such as furosemide). Taking MAO inhibitors with Treximet may cause a serious (possibly fatal) drug interaction. Do not take any MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with Treximet. Most MAO inhibitors should also not be taken for two weeks before treatment with Treximet. Ask your doctor when to start or stop taking Treximet. The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs. Treximet may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, or ketorolac). These drugs are similar to naproxen and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Daily use of naproxen may decrease aspirin's ability to prevent heart attack/stroke. Talk with your doctor about the risks and benefits. Ask about other medications that can be used to treat pain/fever. If you also take any ergotamine medication (such as dihydroergotamine) or other "triptan" drugs (such as zolmitriptan, rizatriptan), you will need to separate your dose of Treximet from your dose of these other medications to lessen the chance of serious side effects. Ask your doctor how long you should wait between your doses of these drugs. Treximet may interfere with certain laboratory tests (including bleeding times, adrenal function tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Treximet.

  • Treximet Side Effects

    What are Treximet side effects?

    Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Treximet may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Treximet as a result of an interaction with other medications.

    Side Effects of Treximet

    The side effects of Treximet may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Treximet. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Treximet may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

    Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Treximet, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Treximet.

    By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Treximet, or any other medication, should contact their physician. General information about Treximet and the side effects associated with Treximet are described in the following:

    Common Treximet Side Effects


    • body fluid retention
    • tinnitus
    • urticaria
    • skin rash
    • abnormal hepatic function tests

    Less Severe

    • constipation
    • drowsy
    • dizziness
    • edema
    • headache disorder
    • nausea
    • heartburn
    • nasal passage irritation
    • dizziness
    • dysgeusia
    • paresthesia
    • flushing
    • nausea
    • vomiting
    • sensation of warmth
    • injection site sequelae
    • vertigo
    • stinging of skin
    • hypesthesia

    Less Frequent Treximet Side Effects


    • purpura
    • hemorrhage
    • blurred vision
    • visual changes
    • ecchymosis
    • polydipsia
    • bruising

    Less Severe

    • hearing loss
    • dyspepsia
    • vertigo
    • hyperhidrosis
    • palpitations
    • diarrhea
    • upper abdominal pain
    • neck stiffness
    • myalgia
    • drowsy
    • muscle weakness
    • hyperhidrosis
    • dysesthesia

    Rare or Very Rare Treximet Side Effects


    • bacterial sepsis
    • non-infective meningitis
    • hypoglycemic disorder
    • hyperkalemia
    • hemolytic anemia
    • pancytopenia
    • aplastic anemia
    • anemia
    • thrombocytopenic disorder
    • agranulocytosis
    • leukopenia
    • eosinophilia
    • acute confusion
    • depression
    • optic neuritis
    • hypertension
    • chronic heart failure
    • heart failure
    • vasculitis
    • thrombotic disorder
    • Loffler syndrome
    • eosinophilic pneumonia
    • bronchospastic pulmonary disease
    • lupus-like syndrome
    • gastric ulcer
    • peptic ulcer
    • gastrointestinal perforation
    • gastrointestinal ulcer
    • hepatic failure
    • colitis
    • hepatitis
    • acute pancreatitis
    • gastrointestinal hemorrhage
    • nephrotic syndrome
    • interstitial nephritis
    • glomerulonephritis
    • renal tubular necrosis
    • renal failure
    • renal papillary necrosis
    • kidney disease with reduction in GFR
    • cystitis
    • hematuria
    • allergic dermatitis
    • erythema multiforme
    • toxic epidermal necrolysis
    • Stevens-Johnson syndrome
    • exfoliative dermatitis
    • pruritus of skin
    • myalgia
    • rectal bleeding
    • fever
    • jaundice
    • wheezing
    • dyspnea
    • chest tightness
    • bloody vomit
    • hyperglycemia
    • anaphylaxis
    • angioedema
    • corneal opacity
    • acute myocardial infarction
    • coronary artery spasm
    • myocardial ischemia
    • ventricular tachycardia
    • ventricular fibrillation
    • ischemic bowel disease
    • seizure disorder
    • chest pain
    • chest tightness
    • dysphagia
    • anaphylaxis
    • serotonin syndrome
    • vision loss
    • abdominal pain with cramps
    • splenic infarction
    • hypersensitivity drug reaction
    • hypertension
    • Raynaud's phenomenon
    • peripheral ischemia
    • intracerebral hemorrhage
    • cerebrovascular accident
    • subarachnoid intracranial hemorrhage
    • angioedema
    • hypotension
    • acquired dystonia
    • bronchospastic pulmonary disease
    • acute myocardial infarction
    • cardiac arrhythmia
    • cerebrovascular accident
    • hypotension
    • pneumonia
    • respiratory depression
    • coma
    • syncope
    • gastrointestinal obstruction
    • lymphadenopathy
    • polyuria
    • proteinuria
    • pulmonary edema
    • seizure disorder
    • tachycardia
    • neutropenic disorder

    Less Severe

    • esophagitis
    • alopecia
    • eructation
    • tremor
    • black tarry stools
    • gastritis
    • menstrual disorder
    • skin photosensitivity
    • muscle weakness
    • concentration difficulty
    • insomnia
    • fatigue
    • appetite changes
    • vomiting
    • symptoms of anxiety
    • visual changes
    • nasal pain
    • jaw pain
    • mouth irritation
    • sore tongue
    • muscle rigidity
    • cramps
    • fatigue
    • sinusitis
    • medication overuse headache
    • palpitations
    • tremor
    • symptoms of anxiety
    • conjunctivitis
    • xerostomia
    • glossitis
    • oliguria
    • papilledema
    • hallucinations
    • stomatitis
    • general weakness
    • paresthesia
    • weight gain
    • weight loss
    • dysuria
    • nervousness
    • erythema nodosum
    • lichen planus
  • Treximet Storage

    Store in the original container at room temperature away from light and moisture. To help protect from moisture, keep the desiccant in the container. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Treximet when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

IMPORTANT DISCLAIMER: All medical content is supplied by a third-party company who is independent from this web site. As such, this web site cannot guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdictions depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.