Zoloft

(Sertraline Hydrochloride)

Zoloft (sertraline) is a brand-name antidepressant from the selective serotonin reuptake inhibitors (SSRIs) class. It is used to treat depression, anxiety disorders and other mental health conditions such as obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD).

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Brand Versions

Zoloft Prescription Required

Strength
25mg
Country
Canada
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Zoloft Prescription Required

Strength
50mg
Country
United Kingdom
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Marketed as Lustral in United Kingdom

Zoloft Prescription Required

Strength
100mg
Country
Turkey
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Marketed as Lustral Special in Turkey

Also available from United Kingdom and Canada
Strength
100mg
Country
United Kingdom
Select Quantity

Marketed as Lustral in United Kingdom

Strength
100mg
Country
Canada
Select Quantity

Marketed as Zoloft in Canada

Generic Versions
What are generics?

Sertraline Hydrochloride Prescription Required

Strength
25mg
Country
Canada
Select Quantity
Sertraline, the Canadian generic version of Zoloft, is available as a capsule in Canada and cannot be split.

Marketed as Auro-Sertraline in Canada

Sertraline Hydrochloride Prescription Required

Strength
50mg
Country
Canada
Select Quantity
Sertraline, the Canadian generic version of Zoloft, is available as a capsule in Canada and cannot be split.

Marketed as Auro-Sertraline in Canada

Sertraline Hydrochloride Prescription Required

Strength
100mg
Country
Canada
Select Quantity
Sertraline, the Canadian generic version of Zoloft, is available as a capsule in Canada and cannot be split.

Marketed as Auro-Sertraline in Canada

Also available from United Kingdom
Strength
100mg
Country
United Kingdom
Select Quantity

Marketed as Sertraline Hydrochloride in United Kingdom

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Important information about Zoloft

How does Zoloft work?

The active ingredient in Zoloft is sertraline. It works by inhibiting the reuptake of serotonin, a neurotransmitter in the brain that plays a key role in regulating mood, anxiety, and overall emotional well-being.

Zoloft comes in an oral tablet or liquid oral solution and is typically taken once daily.

How do you use Zoloft?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Zoloft. However, the following is a synopsis of the general guidelines for the use of Zoloft:

  • Do not crush or chew the oral tablet, Zoloft tablets should be swallowed whole with the help of a liquid
  • Zoloft oral tablets can be taken with or without food
  • If taking Zoloft liquid oral solution with a dropper, it must be diluted before use using water, orange juice, lemonade, ginger ale, or a lemon/lime soda
  • If you are experiencing unpleasant side effects of sertraline, contact your doctor before abruptly stopping Zoloft
  • If you miss your daily dose of sertraline, take it as soon as you remember unless it is almost time for your next one

What are the side effects of Zoloft?

The most common side effects of Zoloft seen in clinical trials as compared to placebo include:

  • Anxiety or nervousness
  • Fatigue or tiredness
  • Nausea, indigestion or diarrhea
  • Loss of appetite
  • Increased sweating
  • Eye pain
  • Agitation
  • Change in sleep habits including trouble sleeping
  • Sexual problems including change in libido or issues with ejaculation
  • Weight gain

Some individuals may experience serious side effects while using Zoloft. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Suicidal thoughts or actions, typically within the first few months of taking the medication
  • New or worsened anxiety disorders or panic attacks
  • Worsened insomnia
  • Worsening agitation or violent thoughts
  • Glaucoma
  • Heart problems
  • Drastic change in behavior, such as talking more than is normal for you
  • Serotonin syndrome symptoms, including dizziness, tremors, rapid heart rate, or seizures
  • Adolescents taking Zoloft may experience changes in weight

These are not all of the possible side effects of Zoloft. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Zoloft?

Before starting Zoloft, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • History of suicidal thoughts or actions
  • History of Major Depressive Disorder (MDD), Bipolar Disorder, Social Anxiety Disorder, Panic Disorder, Premenstrual Dysphoric Disorder (PMDD), Obsessive-Compulsive Disorder (OCD), or Post-Traumatic Stress Disorder (PTSD), or are currently taking medications for these disorders
  • History of allergic reaction to sertraline or any Zoloft ingredients
  • History of bleeding problems or high blood pressure
  • Are taking any other medications containing sertraline, such as sertraline hydrochloride

Are there any contraindications with Zoloft?

If you have any of the following conditions or if any of the following apply to you, please notify your healthcare professional as Zoloft may not be safe for you to use.

  • Have taken or are currently taking a monoamine oxidase inhibitor (MAOI), such as linezolid or methylene blue
  • Have taken or are currently taking an antipsychotic, such as pimozide
  • Have taken or are currently taking disulfiram, such as Antabuse

How long does it take Zoloft to work?

Zoloft typically takes 4 to 6 weeks for optimal results, although people can start feeling benefits within the first few weeks.

What interacts with Zoloft?

When Zoloft is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as warfarin, ibuprofen or naproxen
  • Prescribed opioids, such as tramadol or fentanyl
  • Other antidepressant medications, such as SNRIs
  • Herbal supplements, such as St. John’s Wort

What doses of Zoloft are available?

Zoloft comes in doses of 25, 50, and 100 milligrams. The liquid oral solution currently comes in a dosage of 20 mg/ml. 50 mg is commonly prescribed as a maintenance dose for those diagnosed with depression or other anxiety disorders.

How do I store Zoloft?

Store Zoloft at room temperature in a cool, dry area that is out of reach of children.

Which pharmaceutical company manufactures Zoloft?

Zoloft is manufactured by the pharmaceutical company Pfizer Inc.

Is there a generic version of Zoloft?

Sertraline or sertraline hydrochloride is the generic version of Zoloft.

How do I stop taking Zoloft?

Before stopping Zoloft, speak with your healthcare provider. They can assess your situation, determine if it’s appropriate to stop and guide you through the process. Your doctor may recommend a gradual tapering schedule to reduce the risk of withdrawal symptoms.

Can Zoloft be used if I am pregnant?

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Zoloft is considered safe during pregnancy, but you may be recommended a lower dose depending on your pregnancy stage.

Can Zoloft be used if I am breast feeding?

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

Zoloft is considered safe to use while breastfeeding, but you may be recommended a lower dose.

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Important information about buying Zoloft from UniversalDrugstore™

What happens after I place my order for Zoloft with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Zoloft?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Zoloft?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Zoloft?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Zoloft?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Zoloft?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Zoloft News

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Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.