Differin Gel
Differin Gel (adapalene gel) is a retinoid-based acne treatment for people 12 years of age and older. With consistent use, it can be used to effectively treat acne by helping clear the skin and preventing further breakouts.
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Differin Prescription Required
Differin Prescription Required
Marketed as Differin XP Gel in Canada
Adapalene Prescription Required
Marketed as Adiff Gel in India
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Important information about Differin Gel
How does Differin Gel work?
The active ingredient in Differin Gel is adapalene. Adapalene is a type of topical retinoid that reduces inflammation and promotes increased cell turnover. In the treatment of acne, these properties help to reduce redness and improve overall skin texture and appearance. Consistent use will help decrease the number and severity of pimples and promote the healing of any future ones that develop.
How do you use Differin Gel?
Follow all directions given to you by your doctor or dermatologist and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Differin Gel. However, the following is a synopsis of the general guidelines for the use of Differin Gel:
- Since Differin Gel can increase your sensitivity to the sun, it is best to incorporate it into your nighttime skincare routine.
- Wash your face or the affected area with a gentle, non-medicated, fragrance-free cleanser. Avoid cleansers with alpha-hydroxy or glycolic acids as these in combination with Differin Gel may be too irritating to the skin.
- After washing your face, let the skin dry before applying a thin layer to the entire face or the affected area. You may notice a slight stinging sensation after applying. Differin Gel is for external use only and should not be used anywhere else other than the affected area. Avoid applying the gel around the eye area or on your lips. Avoid getting the gel on any mucus membranes such as those within the nose or the mouth. Avoid applying the gel to broken, irritated, or sunburned skin.
- After letting it dry, apply a moisturizer on top. Wash your hands after using Differin Gel to avoid accidentally transferring the medication to unintended areas.
- Differin Gel is not a spot treatment and should not be used to treat a single pimple.
- Because Differin Gel can increase your risk for sunburns, daily use of a broad-spectrum sunscreen with SPF 30 is very important. An oil-free product may be preferred to avoid clogging your pores and causing further breakouts, blackheads, pimples, or whiteheads. If outdoors for long periods of time, wear protective clothing.
- Avoid skin care products with other active ingredients such as benzoyl peroxide or salicylic acid. Using these in combination with Differin Gel may be too irritating for the skin.
- Avoid the use of waxing and chemical depilatories on areas treated with Differin Gel.
What are the side effects of Differin Gel?
The most common side effects of Differin Gel include:
- Dry skin
- Itchiness
- Skin peeling
- Skin irritation
- Burning or stinging sensation
Some individuals may experience serious side effects while using Differin Gel. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Signs of an allergic reaction such as difficulty breathing, swelling of the lips, eyes or the face, and hives
- Signs of intolerable skin reactions such as redness, scaling, dryness, or a stinging or burning sensation that do not improve with use
These are not all of the possible side effects of Differin Gel. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Differin Gel?
Before starting Differin Gel, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- Other skin problems such as cuts, abrasions, sunburns, or irritated skin that is dry, itchy, or red
- Eczema
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed
Are there any contraindications with Differin Gel?
Do not use Differin Gel if you have:
- An allergy or hypersensitivity to adapalene or any of the other inactive ingredients found in Differin Gel (carbomer 940, edetate disodium, methylparaben, poloxamer 124, propylene glycol, purified water, sodium hydroxide, hydrochloric acid).
How long does it take Differin Gel to work?
With regular use, Differin gel promotes the exfoliation of skin cells to reveal clearer skin over time. While some people may see improvements after 2 weeks, it can take up to 12 weeks to see an effect so it is important to be consistent with your routine. If no improvement is seen at the 12-week mark, consult your healthcare provider on whether Differin Gel is the right treatment for you.
What interacts with Differin Gel?
When Differin Gel is used with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions.
What doses of Differin Gel are available?
Differin Gel is available in the following strengths:
- 0.3% adapalene
There is also an over-the-counter (OTC) version of Differin Gel available that contains a lower strength of adapalene. Consult your doctor, dermatologist, or pharmacist on which product would be best for you.
How do I store Differin Gel?
Differin Gel should be stored at room temperature away from excess heat and out of reach of children. Do not freeze Differin Gel.
Which pharmaceutical company manufactures Differin Gel?
Differin Gel is manufactured by the pharmaceutical company Galderma Laboratories.
Is there a generic version of Differin Gel?
Yes, there is a generic version of the brand name Differin Gel available.
How do I stop taking Differin Gel?
Consult your doctor, dermatologist, or pharmacist before starting, stopping, or changing medications while using Differin Gel. Depending on your results and current experience, they will know what is best to recommend for you in terms of the duration of use.
Can Differin Gel be used if I am pregnant?
It is unknown if Differin Gel can cause harm to the unborn child. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
Can Differin Gel be used if I am breast feeding?
It is unknown if Differin Gel can pass into the breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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What happens after I place my order for Differin-gel with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Differin-gel?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Differin-gel?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Differin-gel?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
How is my medication packaged to ensure privacy and safety?
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Does Universal Drugstore ship medications that require refrigeration or special handling?
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
What are the shipping costs, and does Universal Drugstore offer free delivery?
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Does Universal Drugstore accept Medicare or Medicaid for prescriptions?
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Can I use private health insurance to cover my prescription from Universal Drugstore?
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
How secure is my payment information when ordering from Universal Drugstore?
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Can I order a generic alternative to Differin-gel?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Differin-gel?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Does Universal Drugstore offer discounts or price matching?
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
How can I contact Universal Drugstore for additional support?
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.