Fiasp Vial

The active ingredient in Fiasp is insulin aspart. Insulin aspart is a hormone that operates by lowering the sugar (glucose) levels in your blood. It aids in your body storing and absorbing sugar while also stopping glucose production in your liver.

Fiasp contains niacinamide, also known as vitamin B3, and L-arginine, which allows your body to process it more quickly. It begins to work approximately 2.5 minutes after administration, making it faster to control blood sugar levels than other insulin products.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Fiasp. However, the following is a synopsis of the general guidelines for the use of Fiasp:

• Fiasp is a fast-acting insulin (a type of insulin that is released quickly into your bloodstream). This makes it crucial to take your dose of Fiasp right at the start of a meal or within 20 minutes after you start your meal
• Change your injection site often to avoid developing red, bumpy, or thickened skin. The injection sites are all subcutaneous, which means they go under the skin. Typically, they include the upper arm, abdomen, or thigh

Always use a new needle for each new injection. If you are using a continuous insulin pump, ensure that you change the location of your injection site to avoid damaging your skin

• You will be monitored by your healthcare professional throughout your treatment with Fiasp, including monitoring your blood glucose levels. This will influence the dosage you will receive throughout treatment
• Always check that you are injecting yourself with the correct insulin pen, and read the label before injecting yourself to ensure you are getting the proper insulin dose as prescribed by your doctor
• Never share a Fiasp Flextouch Pen, Penfill cartridge, or Penfill cartridge device with another friend or patient. Sharing needles increases the risk of blood-borne pathogens
• Your Fiasp insulin injection will most likely be taken in combination with either an intermediate or long-acting insulin injection that will often be prescribed to be taken once a day. It may also be taken with oral medications such as metformin.

The most common side effects of Fiasp seen in clinical trials as compared to placebo include:

• Injection site reactions such as itching, rash, or lipodystrophy (pits in skin or thickened skin)
• Weight gain
• Common cold symptoms
• Respiratory tract infections
• Nausea
• Diarrhea

Some individuals may experience serious side effects while using Fiasp. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe hypoglycemia (low blood sugar)
• This may endanger your life
• Some symptoms of low blood sugar include:
• Being anxious or nervous
• Feeling shaky
• Fast heartbeat
• Body chills or sweating
• Confusion
• Feeling sleepy
• Low energy or weakness
• Excessive hunger
• Hypokalemia (low potassium levels). This may be life-threatening
• If you are at risk of hypokalemia, ensure that you speak to your healthcare provider about monitoring your body’s potassium levels.Treatment plans can be made for those at risk of hypokalemia.
• Severe allergic reaction. This has the possibility of including anaphylaxis.
• Get medical attention immediately if you experience any of the following symptoms, including:
• Swelling in your face, throat, or tongue
• Fast heartbeat
• Extreme drowsiness
• Dizziness
• Confusion
• Sweating
• Heart failure
• There is a higher possibility of developing heart failure if you are also taking Fiasp rapid-acting insulin with thiazolidinediones (TZDs) such as rosiglitazone and pioglitazone

These are not all of the possible side effects of Fiasp. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Fiasp, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• A known allergy or hypersensitivity to Fiasp or anything within the Fiasp medication.
• Liver or kidney problems.
• A pregnancy, plan to become pregnant, or are breastfeeding.
• New prescriptions, over-the-counter medications, or supplements that you start taking.

Fiasp (insulin aspart) is contraindicated in the following situations:

• Hypersensitivity to insulin aspart or any of its components.
• Severe hypoglycemia, Fiasp should not be used during episodes of severe low blood sugar without addressing the cause first.

Fiasp (insulin aspart) typically starts working within 15 to 20 minutes after injection, with its peak effect occurring around 1 to 3 hours. It helps lower blood sugar levels quickly, making it suitable for mealtime use. Always follow your doctor's instructions for optimal use and monitoring of blood sugar levels.

When Fiasp is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Atypical antipsychotics such as olanzapine and clozapine
• Corticosteroids
• Diuretics
• Danazol
• Glucagon
• Estrogens
• Niacin
• Isoniazid
• Phenothiazines
• Oral contraceptives
• Progestogens such as those in oral contraceptives)
• Somatropin
• Protease inhibitors
• Sympathomimetic agents such as epinephrine, albuterol, terbutaline
• Thyroid hormones

The following medications have the potential to decrease or increase your blood glucose levels while using Fiasp. You may need to change your dose of Fiasp and/or undergo more glucose monitoring while undergoing treatment. Those medications include:

• Alcohol
• Clonidine
• Beta-blockers
• Lithium salts
• Pentamidine
• This could lead to hypoglycemia (low blood sugar) and later hyperglycemia (high blood sugar).

Some medications may change the signs and symptoms of hypoglycemia. You may need to change your dose of Fiasp and/or undergo more glucose monitoring while undergoing treatment. These medications include:

• Clonidine
• Guanethidine
• Reserpine
• Beta-blockers

Fiasp is available in a concentration of 100 U/mL for use in a FlexTouch pen, PenFill cartridge, or insulin pump, specifically as follows:

• 10 mL multiple-dose vial
• 3 mL single-patient-use PenFill cartridges to be used with a PenFill cartridge device
• 3 mL single-patient-use FIASP FlexTouch
• 1.6 mL single-patient-use PumpCart cartridges to use with a compatible insulin pump

All unopened pens, vials, and penfill cartridges should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Make sure to discard the medication after the expiration date or after it has been at room temperature up to 86°F (30°C) for up to 28 days.

Any opened pens or vials can be stored at room temperature for up to 28 days. They can also be stored in the refrigerator.

Opened penfill cartridges that are currently in use should be kept at room temperature for up to 28 days. Do not put opened penfill cartridges in the refrigerator.

Fiasp is manufactured by Novo Nordisk, Inc., a registered trademark of Novo Nordisk A/S.

Currently, no generic is available for the Fiasp in the United States.

To stop taking Fiasp (insulin aspart), consult your doctor first. If you no longer need insulin therapy or are switching to another treatment, your doctor will guide you on how to adjust your insulin regimen safely. Do not stop taking Fiasp abruptly without medical advice, as it can lead to dangerous blood sugar fluctuations.

Poorly controlled diabetes can increase the risk of harm to you and your unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you. It is not known if Fiasp passes into your breast milk.