Midamor

The active ingredient in Midamor is amiloride hydrochloride, which is a potassium-sparing diuretic. It acts in the kidneys to eliminate excess salt and water from the body while maintaining potassium levels. This helps to lower blood pressure and reduce fluid buildup.

Midamor is often used along with thiazide or loop diuretics.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Midamor. However, the following is a synopsis of the general guidelines for the use of Midamor:

• Take Midamor with meals.
• Your doctor may advise you to eat particular foods or take supplements to keep your potassium levels from dropping too low. Follow the diet and medication regimen provided by your doctor or nutritionist.
• Midamor requires periodic blood testing. An electrocardiograph (ECG), often known as an EKG, may be used to assess your heart function.
• This medication may have an effect on the outcome of certain medical tests. Tell any doctor who treats you that you are taking Midamor. You may need to discontinue this medication at least three days before undergoing a glucose tolerance test.
• Midamor should not be given to patients receiving other potassium-conserving agents, such as spironolactone or triamterene.

Some mild and common side effects of amiloride include:

• Headaches.
• Loss of appetite and weight loss.
• Vomiting and nausea.
• Diarrhea.
• Weakness and fatigue.
• Gas or bloating.
• Dizziness.
• Shortness of breath.
• Stomach pain.
• Constipation.
• Muscle cramps.

Some individuals may experience serious side effects while using Midamor. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Electrolyte changes, including high potassium levels. This can cause nausea, muscle weakness, numbness or tingling, slow or unusual heart rate, or irregular heartbeats.
• Allergic reaction to the medication, such as swelling, skin rash, and hives.

These are not all of the possible side effects of Midamor. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Midamor, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Kidney disease.
• Unable to urinate.
• High potassium levels (hyperkalemia).
• Take potassium supplements.
• Diabetes.
• Cardiovascular disease or congestive heart failure.
• Cirrhosis or other liver disease.
• On a low-salt diet or take salt substitutes.

Boxed Warning

Amiloride, like other potassium-conserving medications, can cause hyperkalaemia (serum potassium levels greater than 5.5 mEq/L), which can be fatal if not treated promptly.

• High potassium levels (more than 5.5 mEq/L).
• Taking additional potassium-boosting drugs or supplements.
• Kidney issues, especially those induced by diabetes.
• Allergic to potassium-sparing diuretics.

Amiloride can begin to reduce blood pressure within 2 hours of a dose. You may need to take this medicine for many weeks to see more consistent changes in your blood pressure. Check your blood pressure at home as prescribed by your doctor. Record your blood pressure readings and bring them to your appointments. This might help your healthcare team understand how well amiloride is working for you and whether your dosage needs to be adjusted.

When Midamor is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Lithium.
• Tacrolimus and cyclosporine are medications used to prevent organ transplant rejection.
• Benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril are examples of angiotensin converting enzyme (ACE) inhibitors.
• Azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, and valsartan are angiotensin II receptor blockers (ARBs).
• Nonsteroidal anti-inflammatory drugs (NSAIDs) include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

Midamor is available in the following dosage form and strength: 5 mg tablet.

The normal dose of this water pill is 5 mg or 10 mg taken orally once per day with food. However, in some cases, daily doses of up to 20 mg may be required.

Store at room temperature and keep out of reach of children.

Merck Frosst is the company that manufactures Midamor.

There are several generic-name versions of Midamor available.

This medicine treats high blood pressure and heart failure, but does not cure them. Even if you are feeling fine, continue to take amiloride. Do not discontinue taking amiloride without consulting your doctor.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.