Buy Periostat Online (Doxycycline Hyclate)
What is Periostat?
What is Periostat?
Periostat is a prescription medication used as part of the treatment for periodontal disease. Periodontitis is a serious gum infection that damages the soft tissue and bone that support the teeth. If left untreated, it can lead to tooth loss and other oral health problems.
Periostat contains doxycycline hyclate, a medication that belongs to the tetracycline antibiotic family. Unlike higher doses of doxycycline that are used to treat bacterial infections, Periostat is given at a lower dose. At this dose, it works mainly to reduce inflammation and slow the breakdown of gum tissue rather than acting as a traditional antibiotic.
Periostat is typically used as an adjunct treatment alongside dental procedures such as scaling and root planing. These procedures remove plaque and tartar from below the gumline. The medication helps support the healing of the gum tissue and improves long-term periodontal health.
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Periostat brand
Periostat 20mg
Prescription RequiredProduct of United Kingdom
Doxycycline Hyclate (generic Periostat)
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Important information about Periostat
The active ingredient in Periostat is doxycycline hyclate.
Doxycycline belongs to a class of medications called tetracycline antibiotics. However, when used at the low dose found in Periostat, its main function is not to kill bacteria but to reduce inflammation in the gum tissue.
Periostat works by inhibiting enzymes that break down connective tissue in the gums. These enzymes contribute to the destruction of gum tissue and bone in periodontal disease.
By reducing the activity of these enzymes, Periostat helps slow the progression of periodontal disease and supports healing after scaling and root planing. This allows the gum tissue to recover and reduces the damage caused by chronic inflammation.
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Periostat. However, the following is a synopsis of the general guidelines for the use of Periostat:
- Take Periostat exactly as prescribed by your healthcare provider.
- The medication is usually taken twice daily.
- Take the tablets on an empty stomach, typically one hour before or two hours after meals.
- Swallow the tablet with a full glass of water to reduce the risk of throat irritation.
- Do not lie down immediately after taking the medication.
- Continue taking the medication for the full treatment period recommended by your healthcare provider.
- Periostat is usually used along with dental procedures such as scaling and root planing to treat periodontal disease.
If you miss a dose, take the next dose at the regular scheduled time. Do not take extra medicine to make up for a missed dose.
Some mild or common side effects of Periostat seen in clinical trials include:
- Headache.
- Diarrhea.
- Upset stomach.
- Heartburn.
Some individuals may experience serious side effects while using Periostat. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Severe allergic reaction, including hives or swelling.
- Severe skin reactions or blistering.
- Severe sunburn or skin sensitivity to sunlight.
- Severe stomach pain or persistent vomiting.
- Severe Joint pain, back pain/ache, or muscle pain.
These are not all of the possible side effects of Periostat. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse reactions to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
Before starting Periostat, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- A history of allergic reactions to tetracycline antibiotics.
- Liver disease.
- Sensitivity to sunlight or a history of severe sunburn.
- Any ongoing bacterial infections.
- Periostat may increase sensitivity to sunlight. Patients should limit sun exposure and use sunscreen while taking this medication.
The medication should only be used as directed and should not be substituted for antibiotics used to treat bacterial infections.
Periostat should not be used in patients with known hypersensitivity to doxycycline or other tetracycline antibiotics.
It should also not be used during pregnancy because tetracycline antibiotics may harm the unborn baby and affect bone and tooth development.
Periostat does not produce immediate results. Because it works by reducing inflammation in the gum tissue, improvement in periodontal disease usually occurs gradually over time.
Clinical studies have shown that consistent use alongside scaling and root planing may improve periodontal health over several months.
When Periostat is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Antacids containing calcium, aluminum, or magnesium, which may reduce the absorption of doxycycline.
- Bismuth subsalicylate, which may interfere with the absorption of the medication.
- Supplements containing calcium or other minerals that may decrease effectiveness.
- Isotretinoin or acitretin, which may increase the risk of certain side effects when used with doxycycline.
- Birth control pills, which may be less effective when taken with tetracycline antibiotics.
Periostat is available as oral tablets containing doxycycline hyclate.
The typical recommended dose for the treatment of adult periodontitis is:
20 mg taken twice daily as directed by a healthcare provider.
The medication is intended for long-term adjunct use alongside dental treatments for periodontal disease.
It should be stored at room temperature, away from the reach of children or pets.
Periostat has been marketed by CollaGenex Pharmaceuticals.
Yes, doxycycline hyclate is available as a generic medication and may also be sold under brand names such as Vibramycin or Monodox.
Do not stop taking Periostat without consulting your healthcare provider. Your dentist or healthcare provider will determine how long the medication should be used as part of periodontal treatment.
Stopping treatment too early may reduce the effectiveness of therapy for periodontal disease.
Periostat is generally not recommended during pregnancy because tetracycline antibiotics may harm the unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant.
Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. Doxycycline may pass into breast milk, and your healthcare provider can help determine the safest option.
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Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
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Jamie Winn, PharmD, is a licensed pharmacist and seasoned medical content reviewer with over 20 years of experience in clinical pharmacy, patient care, and healthcare leadership.
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Shirley is a Medical Writer and first-year Doctor of Pharmacy (PharmD) student at the University of Alberta, where she is building on her strong foundation in health sciences and patient care.
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