Plaquenil

(Hydroxychloroquine Sulfate)

Plaquenil (hydroxychloroquine sulfate) is an antimalarial and disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis and discoid or systemic lupus erythematosus. It is not recommended as a treatment for coronavirus. Originally developed for the treatment of malaria, it was later found effective for managing autoimmune disorders. Taken orally in tablet form, it should be used as directed by your healthcare provider for the best results.

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Brand Versions

Plaquenil Prescription Required

Strength
200mg
Country
Turkey
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Also available from Canada
Strength
200mg
Country
Canada
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Generic Versions
What are generics?

Hydroxychloroquine Sulfate Prescription Required

Strength
200mg
Country
India
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Marketed as HQTOR in India

Also available from Canada
Strength
200mg
Country
Canada
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Marketed as Apo-Hydroxychloroquine in Canada

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Important information about Plaquenil

How does Plaquenil work?

The active ingredient in Plaquenil is hydroxychloroquine sulfate. It reduces inflammation and suppresses the overactive immune response that causes symptoms such as joint pain, fatigue, and skin rashes in autoimmune diseases like lupus. It also helps reduce symptoms of pain and swelling in rheumatoid arthritis. By controlling the immune system, Plaquenil helps alleviate symptoms and slow disease progression, and may also be used for other autoimmune conditions, such as Sjögren's syndrome and malaria.

How do you use Plaquenil?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Plaquenil. However, the following is a synopsis of the general guidelines for the use of Plaquenil:

  • Take Plaquenil with a full glass of water or with food to prevent stomach upset.
  • The dosage of Plaquenil is based on your medical condition, response to treatment, and other medications you may be taking. Do not adjust your dose without consulting your doctor.
  • It may take several weeks or months of consistent use before you experience the full benefits of Plaquenil. Continue taking it even if you feel well.
  • If you are taking Plaquenil for malaria prevention, start the medication 2 weeks before entering an area where malaria is common. Continue taking it during your stay and for 4 weeks after leaving the area.
  • If you are using Plaquenil for the treatment of rheumatoid arthritis or lupus, it is typically taken once or twice daily. Your doctor may adjust your dose over time to achieve the best response.
  • Do not crush, chew, or break Plaquenil tablets. Swallow them whole.
  • If you miss a dose of Plaquenil, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What are the side effects of Plaquenil?

The most common side effects of Plaquenil seen in clinical trials as compared to placebo include:

  • Rash
  • Hair changes
  • Muscle weakness
  • Ringing in the ears
  • Nausea and vomiting
  • Diarrhea
  • Bloating
  • Hair loss
  • Loss of appetite or weight loss
  • Mood changes

Some individuals may experience serious side effects while using Plaquenil. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Serious allergic reactions
  • Skin reactions, including Stevens-Johnson syndrome
  • Tell your doctor immediately if you experience a rash or blisters on your skin
  • Hemolytic anemia (low red blood cell count)
  • Bleeding
  • Serious infections
  • Abnormal heart rhythm (QT prolongation) or cardiomyopathy
  • Suicidal thoughts and/or behavior
  • Retinopathy
  • Severely low blood sugar (hypoglycemia)
  • Notify your doctor immediately if you experience blurred vision, sweating, vision problems, or dizziness
  • Toxicity in your body, such as your eyes or skin
  • Retinal damage
  • This is more common in people who already have damage to the eye’s retina

These are not all of the possible side effects of Plaquenil. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Plaquenil?

Before starting Plaquenil, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • An allergy to any of the ingredients in Plaquenil
  • Plaquenil is also contraindicated with people who are allergic to 4-aminoquinoline drugs
  • Vision problems or eye problems, such as macular degeneration
  • You may need to get regular eye exams while taking Plaquenil
  • Diabetes
  • Heart problems, such as heart failure or heart rhythm disorder
  • Porphyria (a blood disorder)
  • Skin problems (such as psoriasis)
  • Alcoholism
  • A stomach disorder
  • A genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD)

Are there any contraindications with Plaquenil?

Patients with a known hypersensitivity to 4-aminoquinoline compounds.

How long does it take Plaquenil to work?

Plaquenil can take several weeks to months to show noticeable effects, as it works gradually to suppress the immune system and reduce inflammation. In conditions like lupus and rheumatoid arthritis, it may take 4 to 12 weeks to experience significant symptom improvement. It’s important to continue taking the medication as prescribed and attend follow-up appointments to monitor progress.

What interacts with Plaquenil?

When Plaquenil is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any drug interactions, including:

  • Digoxin
  • Ampicillin
  • Rifampicin
  • Methotrexate
  • Cyclosporine
  • Cimetidine
  • Praziquantel
  • Antacids
  • Tamoxifen
  • Heart rhythm medications

What doses of Plaquenil are available?

For children, the dose often changes due to body weight. The tablets, however, only come in one strength of 200 mg.

How do I store Plaquenil?

Store at room temperature, between 68°F to 77°F (20°C to 25°C). Keep it in a dry place away from moisture and heat. Avoid storing it in the bathroom.

Keep Plaquenil in its original container with the lid tightly closed.

Protect it from light. Store Plaquenil out of reach of children and pets to prevent accidental ingestion.

Do not use the medication after the expiration date, and dispose of it properly if it is no longer needed. Consult your pharmacist or local waste disposal company for safe disposal methods.

Which pharmaceutical company manufactures Plaquenil?

Plaquenil is manufactured by Sanofi.

Is there a generic version of Plaquenil?

Currently, there is a lower-cost generic available for the brand name Plaquenil. Related medications include Aralen (chloroquine) and Rheumatrex (methotrexate).

How do I stop taking Plaquenil?

To stop taking Plaquenil, consult your healthcare provider, as they will determine if discontinuation is appropriate for your condition. Abruptly stopping the medication could lead to a flare-up of symptoms or disease progression, so your doctor may recommend gradually tapering the dosage.

Can Plaquenil be used if I am pregnant?

Hydroxychloroquine is often used to treat autoimmune conditions like lupus and rheumatoid arthritis, which can worsen during pregnancy. In these cases, the benefits of controlling the disease may outweigh the potential risks. Some studies suggest that hydroxychloroquine does not significantly increase the risk of congenital malformations or adverse pregnancy outcomes. If hydroxychloroquine is deemed necessary during pregnancy, close monitoring by healthcare providers is recommended to manage any potential risks.

Can Plaquenil be used if I am breast feeding?

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you. Currently, Plaquenil is generally considered safe to use while breastfeeding. However, hydroxychloroquine is excreted into breast milk in small amounts. The amount of drug that passes to the infant through breast milk is generally considered to be low and unlikely to cause harm. While significant adverse effects in breastfed infants are rare, it's important to monitor the infant for any potential side effects, such as diarrhea or unusual symptoms.

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Important information about buying Plaquenil from UniversalDrugstore™

What happens after I place my order for Plaquenil with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Plaquenil?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Plaquenil?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Plaquenil?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Plaquenil?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Plaquenil?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.