Pradaxa(Dabigatran Etexilate Mesylate)
Marketed as Pradax in Canada
Marketed as Pradax in New Zealand
Marketed as Pradax in Canada
Please Note: Manufactured by Boehringer Ingelheim in Germany.
Marketed as Pradax in Canada
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
Pradaxa Drug Information
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You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Dabigatran is used to prevent stroke and harmful blood clots (such as in your legs or lungs) if you have a certain type of irregular heartbeat (atrial fibrillation). Dabigatran is also used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism) and to reduce the risk of them occurring again. Pradaxa may also be used to prevent these blood clots from forming after hip replacement surgery. Dabigatran is an anticoagulant that works by blocking a certain substance (a clotting protein called thrombin) in your blood. This helps to keep blood flowing smoothly in your body. Dabigatran should not be used to prevent blood clots from forming after artificial heart valve replacement. If you have had heart valve surgery, talk to your doctor about the best medication for you. Do not stop taking any medication, including dabigatran, without talking to your doctor first.
Do not stop taking dabigatran unless directed by your doctor. If you stop taking Pradaxa early, you have a higher risk of forming a serious blood clot (such as a stroke, blood clot in the legs/lungs). Your doctor may direct you to take a different "blood thinning" or antiplatelet medication to reduce your risk. Get medical help right away if you have weakness on one side of the body, trouble speaking, sudden vision changes, confusion, chest pain, trouble breathing, pain/warmth/swelling in the legs. People taking Pradaxa may bleed near the spinal cord after certain spinal procedures. Bleeding in this area can cause paralysis that lasts a long time or could become permanent. Ask your doctor about the benefits and risks before any spinal procedure. The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural/spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/enoxaparin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen). Tell your doctor right away if you notice symptoms such as back pain, leg numbness/tingling/weakness, loss of control of the bowels or bladder (incontinence).
How to Use Pradaxa
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking dabigatran and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Pradaxa by mouth with or without food as directed by your doctor, usually twice a day. Children should take the first dose in the morning and the second dose in the evening (about 12 hours apart). To prevent clots after hip or knee replacement surgery, take it as directed by your doctor, usually once a day. Avoid antacids within 24 hours after surgery, or dabigatran may not work as well. If you have stomach upset while taking Pradaxa, take it with food. Swallow the capsules whole with a full glass of water (8 ounces/240 milliliters). Do not crush, chew, or break open the capsules. Doing so can release all of the drug at once, increasing the risk of side effects. Do not put Pradaxa in a pill box or medication reminder box. It must be kept tightly closed in the original bottle (or blister package) to protect it from moisture. See also Storage section for more important details. The Dosage of Pradaxa is based on your medical condition, kidney function, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). For children, the Dosage of Pradaxa is also based on age and weight. Use Pradaxa regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. It is very important to take it exactly as directed. Do not increase your dose or take Pradaxa more often than directed. Do not stop taking Pradaxa without consulting your doctor.
Before taking dabigatran, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Pradaxa may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Pradaxa, tell your doctor or pharmacist your medical history,mechanical heart valve, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), liver disease, recent major injury/surgery, stroke, a certain clotting disorder (antiphospholipid syndrome), frequent falls/injuries. It is important that all your doctors and dentists know that you take dabigatran. Before having surgery or any medical/dental procedures, tell your doctor or dentist that you are taking Pradaxa and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may tell you to stop Pradaxa before surgery. Follow your doctor's directions carefully. Avoid getting injections into the muscles. If you must have an injection into the muscle (for example, a flu shot), ask for it to be given in the arm. This way, it will be easier to check for bleeding and/or apply pressure bandages. Pradaxa may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink. Pradaxa can cause heavy bleeding. To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. If you fall or injure yourself, especially if you hit your head, call your doctor right away. Your doctor may need to check you. Older adults may be at greater risk for bleeding while using Pradaxa. During pregnancy, Pradaxa should be used only when clearly needed. Dabigatran may increase the risk of bleeding in the pregnant woman, the unborn baby, and the newborn baby. Discuss the risks and benefits with your doctor. Your doctor may change the type of medication you use during pregnancy. It is unknown if Pradaxa passes into breast milk. Consult your doctor before breast-feeding.
If you miss a dose of Pradaxa, take it as soon as you remember. If it is less than 6 hours until the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.mifepristone. Other medications can affect the removal of dabigatran from your body, which may affect how dabigatran works. Examples include cobicistat, cyclosporine, dronedarone, ketoconazole, rifampin, and St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others. Aspirin, aspirin-like drugs (salicylates), and nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen, celecoxib) may have effects similar to dabigatran. These drugs may increase the risk of bleeding problems if taken during treatment with dabigatran. Carefully check all prescription/nonprescription product labels (including drugs applied to the skin such as pain-relieving creams) since the products may contain NSAIDs or salicylates. Talk to your doctor about using a different medication (such as acetaminophen) to treat pain/fever. If you have been prescribed low-dose aspirin and related drugs (such as clopidogrel, ticlopidine) for specific medical reasons such as heart attack or stroke prevention, ask your doctor if you should continue taking them or if your prescription should be changed. Consult your doctor or pharmacist for more details.
Pradaxa Side Effects
What are Pradaxa side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Pradaxa may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Pradaxa as a result of an interaction with other medications.
Side Effects of Pradaxa
The side effects of Pradaxa may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Pradaxa. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Pradaxa may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Pradaxa, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Pradaxa.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Pradaxa, or any other medication, should contact their physician. General information about Pradaxa and the side effects associated with Pradaxa are described in the following:
Common Pradaxa Side Effects
- gastrointestinal ulcer
- gastrointestinal hemorrhage
- abdominal distension
- gastroesophageal reflux disease
- upper abdominal pain
Less Frequent Pradaxa Side Effects
Rare or Very Rare Pradaxa Side Effects
- neutropenic disorder
- hypersensitivity drug reaction
- intracranial bleeding
- retroperitoneal hemorrhage
- ocular hemorrhage
- thrombocytopenic disorder
- esophageal ulcer
- spinal epidural hematoma
- erosive esophagitis
- hemorrhagic stroke
- pruritus of skin
- skin rash
See also How To Use section. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep Pradaxa in the original bottle. Do not put Pradaxa in a pill box or medication reminder box. Open only one bottle at a time, and once the bottle is opened, the medication must be thrown away after 4 months. If your capsules are in a blister package, then keep the capsules in the blister package until you are ready to take the medication. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Pradaxa when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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