Zofran Oral Solutionand/or alternativesChemical Ingredient: Ondansetron Hydrochloride
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
4mg/5mL Oral Solution
- Marketed as Zofran Syrup in United Kingdom
- Manufactured by GlaxoSmithKline UK Ltd
- Product of United Kingdom • Shipped from United Kingdom
- Prescription Required
- Manufactured by AA Pharma
- Product of Canada • Shipped from Canada
- Prescription Required
Zofran Oral Solution Drug Information
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Zofran Drug Information
Zofran Oral Solution Overview
Zofran Oral Solution is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
How to Use Zofran Oral Solution
To prevent nausea from chemotherapy, take Zofran Oral Solution by mouth usually within 30 minutes before treatment begins. To prevent nausea from radiation treatment, take Zofran Oral Solution by mouth 1 to 2 hours before the start of your treatment. To prevent nausea after surgery, take ondansetron by mouth 1 hour before the start of surgery. Zofran Oral Solution may be taken with or without food. However, your doctor may tell you not to eat before chemotherapy, radiation, or surgery. If you are using the liquid form of Zofran Oral Solution, use a special measuring spoon or device to measure out your prescribed dose. Do not use a household spoon because you may not get the correct dose. Take any other doses as directed by your doctor. Ondansetron may be taken up to 3 times a day for 1 to 2 days after your chemotherapy or radiation treatment is finished. If you are taking Zofran Oral Solution on a prescribed schedule, take it regularly in order to get the most benefit from it. To help you remember, take it at the same times each day. Dosage of Zofran Oral Solution is based on your medical condition and response to therapy. The dosage for children may also be based on age and weight. The usual maximum dose in patients with severe liver problems is 8 milligrams in 24 hours. Take Zofran Oral Solution exactly as directed. Do not take more medication or take it more often than prescribed. Ask your doctor or pharmacist if you have questions. Inform your doctor if your condition does not improve or if it worsens.
Zofran Oral Solution Precautions
Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other serotonin blockers (e.g., granisetron); or if you have any other allergies. Zofran Oral Solution may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Zofran Oral Solution, tell your doctor or pharmacist your medical history,irregular heartbeat, liver disease, stomach/intestinal problems (e.g., recent abdominal surgery, ileus, swelling). Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using ondansetron,certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using ondansetron safely. Zofran Oral Solution may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Older adults may be more sensitive to the side effects of Zofran Oral Solution, especially QT prolongation (see above). Zofran Oral Solution should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether Zofran Oral Solution passes into breast milk. Consult your doctor before breast-feeding.
Zofran Oral Solution Misdose
Try to take each dose at the scheduled time. If you miss a dose of Zofran Oral Solution, take it as soon as remembered unless it is near the time for the next dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Zofran Oral Solution Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.apomorphine. If you are currently using the medication listed above, tell your doctor or pharmacist before starting ondansetron. Before using Zofran Oral Solution, tell your doctor of all nonprescription and prescription medication you may use,tramadol. Ask your doctor or pharmacist for more details. Many drugs besides ondansetron may affect the heart rhythm (QT prolongation), including dofetilide, pimozide, procainamide, amiodarone, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using ondansetron, report all medications you are currently using to your doctor or pharmacist. The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs. This document does not contain all possible interactions. Therefore, before using Zofran Oral Solution, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Zofran Oral Solution Side Effects
What are Zofran Oral Solution side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Zofran Oral Solution may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Zofran Oral Solution as a result of an interaction with other medications.
Side Effects of Zofran Oral Solution
The side effects of Zofran Oral Solution may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Zofran Oral Solution. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Zofran Oral Solution may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Zofran Oral Solution, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Zofran Oral Solution.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Zofran Oral Solution, or any other medication, should contact their physician. General information about Zofran Oral Solution and the side effects associated with Zofran Oral Solution are described in the following:
Common Zofran Oral Solution Side Effects
- headache disorder
Less Frequent Zofran Oral Solution Side Effects
- general weakness
- skin rash
Rare or Very Rare Zofran Oral Solution Side Effects
- extrapyramidal disease
- transient blindness
- Laryngeal Edema
- bronchospastic pulmonary disease
- acute hepatic failure
- prolonged QT interval
- torsades de pointes
- abnormal hepatic function tests
- abnormal ECG
- Stevens-Johnson Syndrome
- toxic epidermal necrolysis
- symptoms of anxiety
- blurred vision
- pruritus of skin
- urinary retention
Zofran Oral Solution Storage
Tablets may be stored in the refrigerator or at room temperature between 36-86 degrees F (2-30 degrees C). Store the liquid form at room temperature between 59-86 degrees F (15-30 degrees C). Store away from light and moisture. Do not store in the bathroom. Keep all medicines out of reach of children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Zofran Oral Solution when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
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