(Bupropion Hydrochloride/Naltrexone Hydrochloride)
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  • 90/8mg

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Contrave 90/8mg

Contrave 90/8mg

Extended Release Tablets

Marketed as Mysimba in United Kingdom

Prescription required. Manufactured by Orexigen Therapeutics Limited. Product of United Kingdom. Shipped from United Kingdom.

Contrave Drug Information

Are you paying too much for Contrave? Save up to 80% when purchasing your prescription drugs from Universal Drugstore. Our prescription service aspires to conveniently provide you with affordable medications at the lowest prices in Canada and internationally.

We’re working with a number of Canadian and international pharmacy partners, all licensed by their qualified governmental regulatory bodies. By collaborating with our partners, we are able to offer a wide range of brand and generic medications at very competitive prices. You can obtain discount prescription drugs through our online pharmacy. Our prices are already up to 80% lower than your local pharmacy. We are committed to providing you with the best service and prices. This is why we’ll match the price of any of our online pharmacy competitors who require a valid prescription.

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Why Buy Contrave from Universal Drugstore?

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How Long Does It Take to Receive My Contrave Order?

You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.

  • Contrave Overview

    Contrave is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. Contrave is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Naltrexone belongs to a class of drugs known as opiate antagonists, and bupropion is an antidepressant that may help restore the balance of certain natural chemicals (neurotransmitters) in your brain. These two medications work together on separate parts of the brain to reduce appetite and how much you eat. Most opiates should not be used for 7 to 10 days before starting naltrexone, but some opiate drugs (such as methadone) should not be used for 10 to 14 days before starting naltrexone. Ask your doctor or pharmacist for more details. Other forms of naltrexone or bupropion are used to treat a variety of conditions including depression, other mental/mood disorders, smoking cessation, addiction to opioid medication, and alcohol abuse. This combination product is not approved for these other uses. Discuss the risks and benefits of Contrave, as well as other ways to lose weight, with your doctor.

  • Contrave Warnings

    Contrave is a combination of bupropion and naltrexone. Bupropion is an antidepressant used to treat a variety of conditions, including depression and other mental/mood disorders. It can also be prescribed to help with smoking cessation or weight loss. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. If you are using naltrexone/bupropion to lose weight, stop taking Contrave and tell your doctor right away if you have any of the symptoms listed above. Tell your doctor right away if you have any of these symptoms after stopping treatment.

  • How to Use Contrave

    Read the Medication Guide if available from your pharmacist before you start taking naltrexone/bupropion and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Contrave by mouth with a low-fat meal as directed by your doctor, usually twice daily. You may have trouble sleeping when you start taking Contrave. Do not take your evening dose too close to bedtime. Swallow the tablets whole. Do not crush or chew Contrave. Doing so can release all of the drug at once, increasing the risk of side effects such as seizures. The Dosage of Contrave is based on your medical condition, response to treatment, and other medications you may be taking. Your dose will be slowly increased to lower the risk of seizures and to limit side effects such as sleeplessness, symptoms of withdrawal from opiates, and high blood pressure. Do not increase your dose, take it more often, or stop taking it without your doctor's approval. Use Contrave regularly to get the most benefit from it. To help you remember, take it at the same times each day. Tell your doctor if you have not lost weight after 16 weeks on Contrave.

  • Contrave Precautions

    Before taking naltrexone/bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Contrave may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Contrave, tell your doctor or pharmacist your medical history,high blood pressure, heart disease (such as congestive heart failure/recent heart attack), mental/mood disorders (such as bipolar disorder/thoughts of suicide), diabetes, current or recent use (in the last 7-14 days) of any type of opioid drug (such as morphine/methadone/buprenorphine), kidney disease, liver disease (such as cirrhosis), high pressure in the eye (glaucoma), use/abuse of drugs/alcohol, seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumors, arteriovenous malformation, eating disorders such as bulimia/anorexia nervosa). Contrave may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Alcohol may also increase your risk of seizures. After stopping treatment with Contrave, you may be more sensitive to opioids, increasing your risk of possibly life-threatening side effects from opioids (such as decreased breathing, loss of consciousness). Contrave blocks the effects of opiate drugs (including heroin) and similar drugs (opioids). However, large doses of heroin or opioids can overcome this block. Trying to overcome this block is very dangerous and may cause serious injury, loss of consciousness, and death. Follow your doctor's instructions closely. Do not take Contrave with any other product that contains bupropion (such as antidepressants or smoking cessation drugs) since large doses of bupropion are more likely to cause seizures. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of Contrave, especially dizziness. Dizziness can increase the risk of falling. Contrave must not be used during pregnancy. Weight loss during pregnancy is not recommended and may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor right away. Contrave passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

  • Contrave Misdose

    If you miss a dose of Contrave, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

  • Contrave Interactions

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.dextromethorphan, diarrhea medications (such as diphenoxylate), disulfiram, pimozide, opioid pain or cough relievers (such as codeine, hydrocodone), tamoxifen, thioridazine. Taking MAO inhibitors with Contrave may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with Contrave. Most MAO inhibitors should also not be taken for two weeks before and after treatment with Contrave. Ask your doctor when to start or stop taking Contrave. Contrave may interfere with certain medical/laboratory tests (including urine tests for amphetamine, opioid drug tests, and brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Contrave.

  • Contrave Side Effects

    What are Contrave side effects?

    Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Contrave may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Contrave as a result of an interaction with other medications.

    Side Effects of Contrave

    The side effects of Contrave may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Contrave. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Contrave may also occur as a result of an interaction with certain herbal supplements, foods or drinks.

    Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Contrave, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Contrave.

    By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Contrave, or any other medication, should contact their physician. General information about Contrave and the side effects associated with Contrave are described in the following:

    Common Contrave Side Effects


    Less Severe

    • xerostomia
    • constipation
    • dizziness
    • insomnia
    • nausea
    • vomiting
    • diarrhea
    • dream disorder
    • headache disorder

    Less Frequent Contrave Side Effects


    • hypertension
    • urticaria
    • influenza

    Less Severe

    • symptoms of anxiety
    • tinnitus
    • pruritus of skin
    • arthralgia
    • myalgia
    • hyperhidrosis
    • tremor
    • dysgeusia
    • skin rash
    • drug-induced hot flash
    • palpitations
    • urinary tract infection
    • acute abdominal pain
    • nervousness
    • menstrual disorder
    • viral gastroenteritis
    • fatigue
    • irritability
    • drowsy

    Rare or Very Rare Contrave Side Effects


    • suicidal ideation
    • dyspnea
    • dehydration
    • pyelonephritis
    • cholecystitis
    • seizure disorder
    • bloody stools
    • abnormal hepatic function tests
    • suicidal
    • manic disorder
    • drug-induced psychosis
    • homicidal ideation
    • anaphylaxis
    • erythema multiforme
    • Stevens-Johnson syndrome
    • angioedema
    • hepatitis
    • akathisia
    • acute myocardial infarction
    • secondary angle-closure glaucoma
    • opioid withdrawal symptoms
    • pneumonia
    • hypersensitivity drug reaction
    • unconsciousness
    • acute generalized exanthematous pustulosis

    Less Severe

    • vulvovaginal dryness
    • alopecia
    • urinary urgency
    • tension
    • agitation
    • memory impairment
    • lethargy
    • disturbance of attention
    • jaw pain
    • polydipsia
    • fever
    • general weakness
    • lip swelling
    • eructation
    • motion sickness
    • vertigo
    • hostility
    • behavioral disorders
    • aggressive behavior
    • panic disorder
    • abnormal vaginal bleeding
    • hypomania
    • hypoglycemic disorder
    • tachycardia
    • erectile dysfunction
    • malaise
  • Contrave Storage

    Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Contrave when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

IMPORTANT DISCLAIMER: All medical content is supplied by a third-party company who is independent from this web site. As such, this web site cannot guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdictions depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.