Estring Vaginal Ringand/or alternativesChemical Ingredient: Estradiol
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
2mg (0.0075mg/24Hr) Extended Release Vaginal Insert
No generic is available for Estring 2mg (0.0075mg/24Hr).
- Manufactured by Pfizer Ltd
- Product of United Kingdom • Shipped from United Kingdom
- Prescription Required
No generic is available for Estring 2mg (0.0075mg/24Hr).
Estring Vaginal Ring Drug Information
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Estring Drug Information
Estring Vaginal Ring Overview
Estring Vaginal Ring is a female hormone (estrogen). Estring Vaginal Ring is used by women to help reduce vaginal and urinary symptoms of menopause (such as vaginal dryness/burning/itching, painful urination, frequent urges to urinate). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as Estring Vaginal Ring) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.
Estring Vaginal Ring Warnings
Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time Estring Vaginal Ring is used. Therefore, Estring Vaginal Ring should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of Estring Vaginal Ring with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to take Estring Vaginal Ring. If you will be taking Estring Vaginal Ring long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
How to Use Estring Vaginal Ring
Read the Patient Information Leaflet if available from your pharmacist before you start using Estring Vaginal Ring and each time you get a refill. Learn how to use Estring Vaginal Ring properly. If you have any questions, ask your doctor or pharmacist. Wash and dry your hands before handling the ring. Insert the ring high into the vagina as directed. The ring is usually left in place for 90 days and then removed and replaced with a new ring if treatment is to be continued. Do not leave a ring in place for longer than 90 days. Follow the dosing schedule carefully. If the ring is put in properly, you should not be able to feel it and it will not interfere with sexual intercourse. If you are able to feel the ring or feel slight discomfort from the ring, it may mean that the ring is not high enough. Gently push the ring higher with your finger. If the ring falls out of the vagina, rinse the ring with lukewarm water and put it back into the vagina. Contact your doctor if the ring falls out often. The ring is removed by hooking your finger through the ring and gently pulling it out. Contact your doctor if you have trouble removing the ring. Discard the used ring in the trash. Do not flush it down the toilet. It may take 2 to 3 weeks before you get the full benefit of Estring Vaginal Ring. Tell your doctor if your condition does not improve or if it worsens.
Estring Vaginal Ring Precautions
Before using estradiol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Estring Vaginal Ring may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Estring Vaginal Ring, tell your doctor or pharmacist your medical history,vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, mental/mood disorders (such as dementia, depression), a certain blood disorder (porphyria), frequent vaginal infections. Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35. Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. You may need to stop Estring Vaginal Ring for a time or take special precautions. Estring Vaginal Ring may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur. If you get a vaginal infection while using this ring, it is recommended that you remove the ring and resume treatment only after the infection has been treated. Consult your doctor or pharmacist for more information. Estring Vaginal Ring must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. Estring Vaginal Ring passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.
Estring Vaginal Ring Misdose
Not applicable. However, if you have not inserted a new ring after 90 days, contact your doctor or pharmacist right away to establish a new dosing schedule.
Estring Vaginal Ring Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. Estring Vaginal Ring may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Estring Vaginal Ring.
Estring Vaginal Ring Side Effects
What are Estring Vaginal Ring side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Estring Vaginal Ring may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Estring Vaginal Ring as a result of an interaction with other medications.
Side Effects of Estring Vaginal Ring
The side effects of Estring Vaginal Ring may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Estring Vaginal Ring. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Estring Vaginal Ring may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Estring Vaginal Ring, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Estring Vaginal Ring.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Estring Vaginal Ring, or any other medication, should contact their physician. General information about Estring Vaginal Ring and the side effects associated with Estring Vaginal Ring are described in the following:
Common Estring Vaginal Ring Side Effects
- abnormal vaginal bleeding
- vulvovaginal candidiasis
- abdominal pain with cramps
- abdominal distension
Less Frequent Estring Vaginal Ring Side Effects
- urinary tract infection
- uterine cramps
- headache disorder
Rare or Very Rare Estring Vaginal Ring Side Effects
- toxic shock syndrome
- uterine leiomyoma
- neoplasm of breast
- visual changes
- acute myocardial infarction
- pulmonary thromboembolism
- cerebrovascular accident
- deep venous thrombosis
- gallbladder obstruction
- unspecified lump in breast
- nipple discharge
- endometrial hyperplasia
- vaginal irritation
- peripheral edema
- weight gain
- gastrointestinal obstruction
- malignant neoplasm of the uterus
- retinal thrombosis
- fibrocystic breast disease
- vaginal ulcer
- thrombotic disorder
- erythema nodosum
- erythema multiforme
- libido changes
- body fluid retention
- ovarian cyst
- chest pain
- pruritus of skin
- mood changes
Estring Vaginal Ring Storage
Store at room temperature. Do not remove the ring from the pouch until ready for use. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Estring Vaginal Ring when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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