Premarin Vaginal Creamand/or alternativesChemical Ingredient: Estrogens, Conjugated
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
0.625mg/g Vaginal Cream
No generic is available for Premarin 0.625mg/g.
- Manufactured by Pfizer Canada Inc
- Product of Canada • Shipped from Canada
- Prescription Required
No generic is available for Premarin 0.625mg/g.
Premarin Vaginal Cream Drug Information
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Premarin Drug Information
Premarin Vaginal Cream Overview
Premarin Vaginal Cream is a female hormone. Premarin Vaginal Cream is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as Premarin Vaginal Cream) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.
Premarin Vaginal Cream Warnings
Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time Premarin Vaginal Cream is used. Therefore, Premarin Vaginal Cream should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of Premarin Vaginal Cream with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to use Premarin Vaginal Cream. If you will be using Premarin Vaginal Cream long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.
How to Use Premarin Vaginal Cream
Read the Patient Information Leaflet if available from your pharmacist before you start using Premarin Vaginal Cream and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Use Premarin Vaginal Cream as directed by your doctor. Fill the applicator with the medication according to the directions. Insert the applicator high into the vagina and press the plunger to release the medication. Clean the applicator with warm soapy water and rinse well. Do not boil or use hot water to clean the applicator. The Dosage of Premarin Vaginal Cream is based on your medical condition and response to treatment. Use Premarin Vaginal Cream regularly to get the most benefit from it. Follow your dosing schedule carefully. Do not increase your dose or use Premarin Vaginal Cream more often or for a longer time than directed. Tell your doctor if your condition does not improve or if it worsens.
Premarin Vaginal Cream Precautions
Before using Premarin Vaginal Cream, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Premarin Vaginal Cream may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Premarin Vaginal Cream, tell your doctor or pharmacist your medical history,vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, mental/mood disorders (such as dementia, depression), certain blood disorder (porphyria). Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35. Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. You may need to stop Premarin Vaginal Cream for a time or take special precautions. Premarin Vaginal Cream may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur. Some estrogen products contain mineral oil which can weaken rubber products such as latex condoms, cervical caps, and diaphragms and lead to their failure. Consult your pharmacist if you are unsure if your product contains mineral oil. If it does, talk to your doctor about other birth control products (such as polyurethane condoms) while you are using Premarin Vaginal Cream. Premarin Vaginal Cream must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. Premarin Vaginal Cream passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.
Premarin Vaginal Cream Misdose
If you miss a dose of Premarin Vaginal Cream, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Premarin Vaginal Cream Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. Premarin Vaginal Cream may interfere with certain laboratory tests (including metyrapone test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Premarin Vaginal Cream.
Premarin Vaginal Cream Side Effects
What are Premarin Vaginal Cream side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Premarin Vaginal Cream may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Premarin Vaginal Cream as a result of an interaction with other medications.
Side Effects of Premarin Vaginal Cream
The side effects of Premarin Vaginal Cream may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Premarin Vaginal Cream. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Premarin Vaginal Cream may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Premarin Vaginal Cream, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Premarin Vaginal Cream.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Premarin Vaginal Cream, or any other medication, should contact their physician. General information about Premarin Vaginal Cream and the side effects associated with Premarin Vaginal Cream are described in the following:
Common Premarin Vaginal Cream Side Effects
- weight gain
- weight gain
- headache disorder
- back pain
- abdominal distension
- vulvovaginal candidiasis
Less Frequent Premarin Vaginal Cream Side Effects
- libido changes
- acne vulgaris
- pruritus of skin
- general weakness
- pelvic pain
Rare or Very Rare Premarin Vaginal Cream Side Effects
- uterine leiomyoma
- malignant neoplasm of the ovary
- endometrial carcinoma
- neoplasm of breast
- acute myocardial infarction
- pulmonary thromboembolism
- cerebrovascular accident
- deep venous thrombosis
- gallbladder obstruction
- endometrial hyperplasia
- thromboembolic disorder
- retinal thrombosis
- precocious puberty
- hypersensitivity drug reaction
- vaginal discharge
- nipple discharge
- vaginal irritation
- abnormal vaginal bleeding
- body fluid retention
- abdominal pain with cramps
- genital organ pruritus
Premarin Vaginal Cream Storage
Store at room temperature. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Premarin Vaginal Cream when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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