What Is Exforge HCT and How Does It Work?
Managing high blood pressure often requires consistent medication, but the cost ...
Brand-name Exforge HCT (amlodipine, valsartan, hydrochlorothiazide) is a prescription antihypertensive medication that combines a calcium channel blocker, an angiotensin II receptor blocker, and a thiazide diuretic. It is indicated for the treatment of hypertension in adults, but it is not indicated for initial therapy. Some common side effects are dizziness, edema, and headache.
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Exforge HCT contains three medicines that help lower high blood pressure in different ways. Amlodipine is a dihydropyridine calcium channel blocker that helps relax blood vessels, valsartan is an angiotensin receptor blocker (ARB), and hydrochlorothiazide is a diuretic that helps the body remove extra salt and water.
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Exforge HCT. However, the following is a synopsis of the general guidelines for the use of Exforge HCT:
Some mild or common side effects of Exforge HCT seen in clinical trials as compared to placebo include:
Some individuals may experience serious side effects while using Exforge HCT. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
These are not all of the possible side effects of Exforge HCT. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
Before starting Exforge HCT, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:
The dose may be increased after 2 weeks, and the full blood pressure-lowering effect was achieved 2 weeks after being on the maximal dose. Your healthcare provider may titrate treatment based on how your blood pressure responds.
When Exforge HCT is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
The following doses are available (amlodipine/valsartan/hydrochlorothiazide mg):
It should be stored at room temperature, out of the reach of children and pets.
It is manufactured by Novartis Pharmaceuticals.
Yes, it is available from many manufacturers of generic drugs.
Do not stop taking Exforge HCT without medical advice from your healthcare provider. Stopping blood pressure medicine on your own may make hypertension harder to control.
Exforge HCT should be avoided in pregnancy. Drugs that act directly on the renin-angiotensin system can cause injury or death to an unborn baby, so treatment should be stopped as soon as pregnancy is detected.
Amlodipine and valsartan are not known to be excreted in human milk in this label, but thiazides are excreted in human milk.
Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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Click to joinWe ship to destinations within the United States, including Alaska and Hawaii, as well as internationally. Delivery typically takes about 2 weeks for orders shipped within the U.S. and Canada, and about 4 weeks for international orders, depending on your location and customs processing.
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Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
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Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.
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Managing high blood pressure often requires consistent medication, but the cost ...
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Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Jamie Winn, PharmD, is a licensed pharmacist and seasoned medical content reviewer with over 20 years of experience in clinical pharmacy, patient care, and healthcare leadership.
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Shirley is a Medical Writer and first-year Doctor of Pharmacy (PharmD) student at the University of Alberta, where she is building on her strong foundation in health sciences and patient care.
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