Cardizem CD

The active ingredient in Cardizem CD is diltiazem hydrochloride. It works by affecting the movement of calcium ions, thereby inhibiting muscle contraction and allowing the blood vessels to relax to help lower blood pressure. It also allows your heart to get more oxygen to help with chest pain.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Cardizem CD. However, the following is a synopsis of the general guidelines for the use of Cardizem CD:

• This medication can be taken once daily. Ensure the capsule is swallowed whole.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

The most common side effects of Cardizem CD include:

• Headache
• Nausea
• Swelling in your legs and feet (edema)
• Dizziness and lightheadedness
• Constipation
• Dry mouth

Some individuals may experience serious side effects while using Cardizem CD. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Worsening heart failure: chest pain, shortness of breath, dizziness, fatigue, swelling, or bloating
• Heart rhythm changes: chest pain, irregular heartbeat, a slow heart rate (bradycardia)
• Hepatic (liver) damage: dark urine, loss of appetite, pain or tenderness in the upper stomach, and yellowing of the eyes or skin
• Hypotension (low blood pressure)
• Severe allergic reaction: skin reactions including a skin rash or hives, trouble breathing, Stevens-Johnson syndrome, or toxic epidermal necrolysis

These are not all of the possible side effects of Cardizem CD. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Cardizem CD, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Cardiovascular conditions, including sick sinus syndrome or AV block (unless you have a pacemaker)
• Known allergy to this medication
• Liver disease
• Low blood pressure
• Heart disease, including congestive heart failure, heart attack, and heart block
• Heart rhythm disorders (arrhythmias), including ventricular fibrillation and atrial fibrillation

• Sick sinus syndrome or AV block (except if you have a ventricular pacemaker)
• Known allergy to Cardizem CD or any of its inactive ingredients
• Uncontrolled hypotension
• Pulmonary congestion

The effects of diltiazem can take several weeks to fully work.

When Cardizem CD is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Amiodarone
• Benzodiazepines
• Digoxin
• Atazanavir
• Cimetidine
• Quinidine
• St. John's wort
• Rifampin
• Buspirone
• Cyclosporine
• Sirolimus
• Clonidine
• Ivabradine
• Cholesterol-lowering medications, including lovastatin and simvastatin
• Midazolam
• Triazolam
• Carbamazepine
• Anti-hypertensives including beta-blockers

The dosage forms of diltiazem available include extended-release capsules, extended-release tablets, and regular oral tablets. Cardizem CD is an extended-release capsule available in strengths of 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg.

Store Cardizem CD in a dry place at room temperature and out of reach of children.

The manufacturer of Cardizem CD is Bausch Health Companies Inc.

There are lower-cost alternatives to the brand-name Cardizem CD.

Before stopping this medication, consult your healthcare provider. Suddenly stopping Cardizem CD can lead to an elevation in blood pressure and heart rate, which can increase your risk of heart attack, stroke, and chest pain.

There are no well-controlled studies of pregnant women taking Cardizem CD. It should only be used if the possible benefits justify the possible risk to the unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Diltiazem is passed into breast milk in small amounts. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.