Buy Ismo Online

(Isosorbide Mononitrate)

The active ingredient in Ismo is isosorbide mononitrate. It belongs to a group of medications called nitrates, which also contain isosorbide dinitrate and nitroglycerin.

Isosorbide mononitrate works by relaxing and widening blood vessels, a process known as vasodilation. It acts on smooth muscle in the vessel walls by increasing the levels of nitric oxide. This helps blood vessels expand, allowing blood to flow more easily.

As a result, it reduces the workload on the heart so it does not have to work as hard to pump blood. This reduces pressure on the heart and helps prevent chest pain. It may also improve oxygen supply to the heart muscle, which is important in conditions like angina and ischemic heart disease.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Ismo. However, the following is a synopsis of the general guidelines for the use of Ismo:

• Ismo is usually taken by mouth, with or without food. It may be prescribed as immediate-release or extended-release tablets, depending on your treatment plan.
• Take the medication at the same time each day to maintain consistent levels in your body. Swallow tablets whole and do not crush or chew extended-release forms.
• If you miss a dose, take it as soon as you remember unless it is close to your next dose.
• Use caution when standing up quickly, as dizziness or lightheadedness may occur.
• Avoid drinking alcohol, as it may increase the risk of low blood pressure and side effects.

Some mild or common side effects of Ismo seen in clinical trials as compared to placebo include:

• Headache.
• Lightheadedness.
• Flushing.
• Low blood pressure (hypotension).
• Nausea.
• Increased heart rate.

Some individuals may experience serious side effects while using Ismo. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe low blood pressure causing fainting.
• Trouble breathing.
• Rapid or irregular heart rate.
• Signs of an allergic reaction - hives, rash, swelling, severe dizziness, and shortness of breath.
• Symptoms of a heart attack - chest pain spreading to the arm or jaw.

These are not all of the possible side effects of Ismo. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Ismo, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• History of low blood pressure (hypotension).
• Recent heart attack or heart failure.
• Hypertrophic cardiomyopathy.
• Anemia.
• Kidney or liver disease.
• History of allergic reaction to nitrates.
• Dehydration or low fluid levels.

• Are allergic to isosorbide mononitrate or similar drugs.
• Are taking medications for erectile dysfunction such as sildenafil, tadalafil, vardenafil, or avanafil.
• Are using riociguat.

Ismo begins to work within about 30 to 60 minutes after taking a dose. However, it is designed for prevention, not immediate relief of chest pain. Extended-release tablets may provide longer-lasting effects throughout the day. It may take several days of regular use to experience the full benefit in preventing angina episodes.

When Ismo is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Medications for erectile dysfunction (sildenafil, tadalafil, vardenafil, avanafil).
• Riociguat.
• Other nitrates (nitroglycerin, isosorbide dinitrate).
• Blood pressure medications.
• Alcohol.
• Certain supplements that may lower blood pressure.

Ismo is available in tablet form in different strengths. Your healthcare provider will determine the correct dose based on your condition and response to treatment. Dosing schedules may vary, especially with extended-release tablets designed for once-daily use.

Store Ismo at room temperature, away from moisture and heat. Keep the medication in its original container and tightly closed. Keep out of reach of children. If there is an overdose, contact a poison control center or seek emergency medical care right away.

Ismo has been manufactured by West-ward Pharmaceutical Corp.

Ismo is available as a generic medication called isosorbide mononitrate. Generic versions offer the same active ingredient and are often more affordable. Other brand names for similar medications include Imdur and Monoket.

Do not stop taking Ismo suddenly without consulting your healthcare provider for medical advice. Stopping abruptly may increase the risk of angina or chest pain. Your doctor may gradually reduce your dose to safely discontinue treatment.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you. There is limited information on the use of isosorbide mononitrate during pregnancy, so it should only be used if clearly needed.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you. It is not fully known if isosorbide mononitrate passes into breast milk, so your healthcare provider will help weigh the benefits and risks.