Serc

The active ingredient in Serc is betahistine hydrochloride. The pharmacology of betahistine is that it acts as a histamine H1-receptor agonist and a histamine H3-receptor antagonist. The effects of betahistine on the histamine receptors result in the inhibition of vestibular nuclei activity, modulation of vestibular compensation, and increased blood flow in the inner ear. The increased blood flow and vasodilation relieve pressure in the inner ear, and this treats the symptoms of tinnitus, hearing loss, nausea, and vomiting.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Serc. However, the following is a synopsis of the general guidelines for the use of Serc:

• The recommended dose of Serc for adults is 24 to 48 mg in 2 to 3 divided doses. An example dosing schedule could be to take 16 mg by mouth three times a day (total is 48 mg per day). Your healthcare professional may recommend different doses for different vestibular disorders and patient characteristics.
• It is recommended to take Serc with food to prevent stomach upset.
• If you miss a dose, skip the missed dose. Continue taking the next dose of your regular dosing schedule.

The most common side effects of Serc seen in clinical trials as compared to placebo include:

• Skin rashes.
• Stomach pain.
• Headache.
• Nausea.
• Vomiting.
• Bloating.

Some individuals may experience serious side effects while using Serc. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Allergic reaction. Symptoms include hives, rash, itching, swelling of the face, mouth, or lips.
• Confusion.
• Hallucinations.
• Low blood pressure and fainting.

These are not all of the possible side effects of Serc. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Serc, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether any of the following apply:

• Asthma. This is because asthmatic patients should use Serc with caution.
• Liver problems.
• Younger than 18 years old.
• Pregnant, plan to become pregnant, or are breastfeeding.
• Serc will likely not affect your ability to drive or use machinery; however, the symptoms you are being treated for (e.g., vertigo associated with Ménière’s disease) can affect this. Do not drive or use machinery if you are experiencing symptoms such as nausea, dizziness, spinning sensation, hearing loss, etc.

• Allergic reaction to betahistine medications or any of the ingredients in the formulation.
• Peptic (stomach) ulcer or a history of peptic ulcers.
• Phaeochromocytoma.

The pharmacokinetics of Serc are that it is rapidly absorbed into the body. You may see positive effects within a few days; however, it may take a couple of weeks for the full effect.

When Serc is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Antihistamines.
• Monoamine-oxidase inhibitors (MAOIs).

Serc is available as 16 mg and 24 mg tablets.

Store Serc at room temperature, keep away from children and pets.

Viatris Pharma company manufactures Serc (betahistine hydrochloride).

The brand name is Serc (betahistine hydrochloride). The generic version is available and it is betahistine hydrochloride or betahistine dihydrochloride.

Don’t stop taking Serc without consulting your healthcare professional. You may worsen symptoms of balance disorders like Ménière’s disease because Serc is used for the treatment of Ménière’s disease.

Serc should only be used in pregnancy if the benefits outweigh the risks. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

It is not known if Serc passes into the breastmilk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.