Neoral

(Cyclosporine)

Neoral (cyclosporine) is a brand-name immunosuppressant that is used to avoid transplanted organ rejection following a kidney, liver, or heart transplant. It can also be used to treat severe rheumatoid arthritis and psoriasis. It is commonly taken in conjunction with other drugs, such as steroids or methotrexate, and carries an increased risk of infection and cancer.

Common brand names of cyclosporine are Neoral, Gengraf, and Sandimmune. Cyclosporine modified (Neoral) and cyclosporine (Sandimmune) are similar formulations but are absorbed differently in the body. Cyclosporine modified (Neoral) is a newer drug with better and more consistent absorption than equal doses of cyclosporine (Sandimmune). Both drugs can help reduce organ transplant rejection, but they are not interchangeable.

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Brand Versions

Neoral Prescription Required

Strength
10mg
Country
Canada
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Also available from United Kingdom
Strength
10mg
Country
United Kingdom
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Neoral Prescription Required

Strength
25mg
Country
New Zealand
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Also available from Canada and Turkey
Strength
25mg
Country
Canada
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Strength
25mg
Country
Turkey
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Please note that this item is currently on backorder and may require additional delivery time.

Neoral Prescription Required

Strength
50mg
Country
New Zealand
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Neoral Prescription Required

Strength
100mg
Country
New Zealand
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Generic Versions
What are generics?

Cyclosporine Prescription Required

Strength
25mg
Country
India
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Marketed as Panimun Bioral in India

Also available from United Kingdom and Canada
Strength
25mg
Country
United Kingdom
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Marketed as Ciclosporin in United Kingdom

Strength
25mg
Country
Canada
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Marketed as Sandoz-Cyclosporine in Canada

Cyclosporine Prescription Required

Strength
50mg
Country
India
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Marketed as Psorid in India

Also available from Canada
Strength
50mg
Country
Canada
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Marketed as Sandoz-Cyclosporine in Canada

Cyclosporine Prescription Required

Strength
100mg
Country
India
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Marketed as Arpimune-ME in India

Also available from United Kingdom
Strength
100mg
Country
United Kingdom
Select Quantity

Marketed as Ciclosporine in United Kingdom

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Important information about Neoral

How does Neoral work?

The active ingredient in Neoral is cyclosporine. It is an immunosuppressant, which means it reduces (or suppresses) the activity of your immune system. When you have an organ transplant, your body treats the new organ as a foreign object, and your immune system works to reject it.

Neoral can also help treat illnesses caused by an overactive immune system, such as psoriasis and rheumatoid arthritis. These are autoimmune illnesses, which occur when your immune system misidentifies and destroys healthy tissue in your body as a foreign item.

Neoral works by reducing your immune system's ability to reject the new organ or attack healthy cells in your body.

How do you use Neoral?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Neoral. However, the following is a synopsis of the general guidelines for the use of Neoral:

  • Take with or without food, but follow the same procedure each time. Neoral oral solution should be mixed with orange juice or apple juice that is at room temperature.
  • Take sirolimus 4 hours after taking Neoral (modified cyclosporine).
  • Take Neoral (cyclosporine capsules, modified) at the same time every day.
  • Even if you feel fine, continue to take Neoral (cyclosporine capsules, modified) as prescribed by your doctor or other health care professional.
  • If you are using Neoral oral solution, only use the dosage syringe that came with the original packaging to measure your dose. If you're unsure whether you're using the correct syringe, ask your pharmacist. Avoid using kitchen spoons since they will give you an inaccurate dos

What are the side effects of Neoral?

The most common side effects of Neoral seen in clinical trials include:

For organ transplant:

  • Shaking.
  • Kidney issues.
  • Excessive hair growth.
  • High blood pressure.
  • Infections.
  • Nausea or vomiting.
  • Urinary tract infection.

For rheumatoid arthritis:

  • High blood pressure.
  • Headaches.
  • Stomach pain.
  • Muscle cramps.
  • Respiratory infections.

For psoriasis:

  • Pain.
  • High blood pressure.
  • Kidney problems.
  • High triglycerides.
  • Weight loss.
  • Hot flashes or sweating.

Some individuals may experience serious side effects while using Neoral. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • High blood pressure (hypertension): headaches, difficulty breathing, chest pain or pressure, blurred vision, fast heartbeat, nosebleeds, and confusion.
  • Kidney disease: decreased urine production, swelling in the feet or legs, shortness of breath, fatigue, weakness, muscle cramps, nausea, vomiting, and confusion.
  • Liver disease: yellowing of the skin or eyes (jaundice), stomach pain or swelling, loss of appetite, dark urine, nausea, vomiting, fatigue, weakness, and confusion.
  • Serious viral infections: Muscle weakness, lack of interest or emotion, disorientation, memory issues, loss of balance or coordination, and paralysis.
  • Optic nerve swelling: Impaired vision, double vision, visual loss, headache, nausea, or vomiting.
  • Brain damage: Vision problems, loss of vision, loss of muscle control, mobility disorders, mental conditions, seizures, and loss of consciousness.

These are not all of the possible side effects of Neoral. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Neoral?

Before starting Neoral, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • Neoral (modified cyclosporine capsules) can have an increased risk of infections, lymphoma, other malignancies, kidney issues, and high blood pressure.
  • Wash your hands frequently and avoid those who have illnesses, colds, or flu.
  • If you see any signs of infection, allergic reactions, skin abnormalities, or renal problems, contact your doctor immediately.
  • Neoral can lower blood cells that help your body fight infections.
  • If you take Neoral for psoriasis after trying other therapies, your risk of developing skin cancer may increase. Avoid prolonged sun exposure and use sunscreen.
  • Do not switch brands of cyclosporine without first talking to your doctor.
  • Neoral interacts with a variety of medications and health issues. Before beginning any medicine, inform your doctor about all current prescriptions and health concerns.
  • While taking Neoral, avoid grapefruit, grapefruit juice, potassium-containing products, and alcohol.
  • Monitor your blood pressure, renal function, and blood sugar levels as directed by your doctor.
  • Visit your doctor and dentist regularly, and get your skin checked.
  • Neoral should be used with caution by older persons and children.
  • Avoid vaccines without a doctor's approval since they may not work as expected.
  • Monitor for adverse effects such as disorientation, seizures, visual problems, or gout attacks, and notify your doctor.
  • Avoid medicines for high cholesterol such as statins.

Are there any contraindications with Neoral?

Contraindications are certain health problems or situations in which a person should avoid taking a drug for safety reasons. If you have any of the below conditions or if any of the following apply to you, please notify your healthcare professional because Cyclosporine modified (Neoral) is not safe for you to take.

  • Kidney issues.
  • Uncontrolled blood pressure.
  • Currently using phototherapy (PUVA or UVB therapy).
  • Currently utilizing methotrexate or other immunosuppressants.
  • Currently using coal tar.
  • Currently undergoing radiation therapy.
  • Kidney issues.
  • Uncontrolled blood pressure.
  • Currently using phototherapy (PUVA or UVB therapy).
  • Currently utilizing methotrexate or other immunosuppressants.
  • Currently using coal tar.
  • Currently undergoing radiation therapy.
  • Kidney issues.

How long does it take Neoral to work?

You will normally take Neoral for a few months to determine whether Neoral will improve your condition. If Neoral is effective, your doctor may reduce the dose, and you will continue treatment at the lowest level that is appropriate for you.

What interacts with Neoral?

When Neoral is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Aliskiren, amiodarone, bosentan, dabigatran, orlistat, spironolactone, or triamterene.
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen.
  • Tacrolimus.
  • St. John’s wort.
  • Allopurinol.
  • Ambrisentan.
  • Amphotericin b.
  • Carbamazepine.
  • Cimetidine.
  • Corticosteroids.
  • Colchicine.
  • Danazol.
  • Digoxin.
  • Diltiazem.
  • Ketoconazole.
  • Melphalan.
  • Metoclopramide.
  • Octreotide.
  • Phenytoin.
  • Voriconazole.
  • Verapamil.
  • Itraconazole.

What doses of Neoral are available?

Typical Dosing for Cyclosporine Modified (Neoral):

Transplants (Kidney, Liver, Heart): Doses depend on the organ, rejection risk, tolerance, and lab results.

Kidney transplant: 6–12 mg/kg daily, split into two doses.

Liver transplant: 4–12 mg/kg daily, split into two doses.

Heart transplant: 4–10 mg/kg daily, split into two doses.

Rheumatoid Arthritis and Psoriasis:

Starting dose: 2.5 mg/kg daily, split into two doses.

Maximum dose: 4 mg/kg daily, split into two doses.

Take a missed dose as soon as you remember, but if it’s close to your next dose, skip the missed dose and continue with your regular schedule; do not take two doses at once or extra doses.

How do I store Neoral?

Store at room temperature, in a cool dry place, and out of reach of children.

Which pharmaceutical company manufactures Neoral?

Novartis is the pharmaceutical company that manufactures Neoral.

Is there a generic version of Neoral?

There are several lower-cost generic versions available of Neoral.

How do I stop taking Neoral?

Take Neoral precisely as directed and at the same time every day. Never discontinue this medicine unless directed to do so by a transplant surgeon or your healthcare practitioner.

Can Neoral be used if I am pregnant?

Neoral is not recommended during pregnancy. There hasn't been enough research to determine the safety of Neoral during human pregnancy, but animal studies have shown that it can cause major injury and death to newborns. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Can Neoral be used if I am breast feeding?

Neoral is not suggested for breastfeeding. There haven't been enough trials to determine the safety of Neoral while nursing, but it can transfer into human breast milk. Neoral also contains a considerable amount of alcohol, which can enter breast milk and cause major harm to your breastfed child.

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Important information about buying Neoral from UniversalDrugstore™

What happens after I place my order for Neoral with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Neoral?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Neoral?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Neoral?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Neoral?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Neoral?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.