Plavix

(Clopidogrel Bisulfate)

Plavix (clopidogrel) is used to prevent heart attack and stroke in certain people who are at an increased risk for them. It belongs to a class of drugs called antiplatelet drugs, which work by inhibiting platelets (blood cells) from sticking together. Plavix is an oral tablet you typically take once a day.

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Brand Versions

Plavix Prescription Required

Strength
75mg
Country
India
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Manufactured by Sanofi Aventis in France.
Also available from Turkey and United Kingdom
Strength
75mg
Country
Turkey
Select Quantity
Manufactured by Sanofi Aventis in France.
Strength
75mg
Country
United Kingdom
Select Quantity

Plavix Prescription Required

Strength
300mg
Country
United Kingdom
Select Quantity
Generic Versions
What are generics?

Clopidogrel Bisulfate Prescription Required

Strength
75mg
Country
United States
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Clopidogrel Bisulfate Prescription Required

Strength
300mg
Country
India
Select Quantity

Marketed as Clavix in India

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Important information about Plavix

How does Plavix work?

The active ingredient in Plavix is clopidogrel. It works by binding to P2Y 12 receptors on platelets. By blocking this receptor, Plavix prevents platelets from clumping together, thereby reducing the formation of blood clots.

The inhibition of platelet aggregation by Plavix is essential in preventing the occurrence of heart attacks and strokes. When blood clots form within the blood vessels, they can block the flow of blood, leading to potentially life-threatening events. By ensuring smooth blood flow, Plavix not only safeguards against these incidents but also improves overall cardiovascular health.

Plavix is primarily used to reduce the risk of cardiovascular events in individuals with a history of heart attacks (myocardial infarction), strokes in people who have had a recent stroke (usually ischemic stroke), or peripheral arterial disease. It is commonly prescribed to patients who have undergone procedures such as coronary stenting, percutaneous coronary intervention, or coronary artery bypass grafting, as these interventions can increase the risk of blood clot formation. It is also used with patients who have heart disease or who have severe chest pain.

Additionally, Plavix may be prescribed in combination with aspirin for individuals with acute coronary syndrome. Acute coronary syndrome is a condition characterized by reduced blood flow to the heart, and includes non-ST segment elevation myocardial infarction (NSTEMI) and unstable angina). This combination therapy further reduces the risk of cardiovascular events by targeting different aspects of platelet activation.

Off-label, it is prescribed for the treatment of atrial fibrillation.

How do you use Plavix?

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Plavix. However, the following is a synopsis of the general guidelines for the use of Plavix:

  • Follow Prescribed Dosage: Take Plavix exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Your loading dose may be different from your maintenance dose.
  • Take with or without Food: Plavix can be taken with or without food. Follow your doctor's instructions regarding any specific dietary recommendations.
  • Timing: Take Plavix at the same time each day to help remember your dose.
  • Swallow Whole: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Avoid Certain Activities: Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
  • Medical Procedures: Inform your healthcare providers, including dentists, that you are taking Plavix before any surgeries or dental procedures.
  • Missed Dose: If you miss a dose of Plavix, it is advisable to take it as soon as you remember. However, if it is close to the time for your next dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Regular Check-ups: Keep regular appointments with your doctor to monitor your condition and the effectiveness of the medication.

What are the side effects of Plavix?

The most common side effects of Plavix include:

  • Major bleeding
  • Minor bleeding

Some other possible side effects include:

-Itchiness

-Bruising

  • Stomach and intestinal ulcers
  • Nosebleeds
  • Changes in taste
  • Headache
  • Confusion

Some individuals may experience serious side effects while using Plavix. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Thrombotic thrombocytopenic purpura (a blood clotting problem, also known as TTP)
  • Severe bleeding
  • Symptoms could include diarrhea or vomit that has blood in it or looks like coffee grounds.
  • Severe allergic reaction
  • Symptoms could include hives, shortness of breath, or swelling on your face, lips, and mouth.

These are not all of the possible side effects of Plavix. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

What are the warnings or precautions for Plavix?

Before starting Plavix, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

  • A bleeding disorder or a blood clotting disorder
  • Ever had stomach ulcers or bleeding in the brain
  • Any known allergies
  • This includes an allergy to thienopyridines, such as prasugrel
  • Any active bleeding

Boxed Warning

Plavix carries a boxed warning, stating that there is a diminished antiplatelet effect in patients who have loss-of-function alleles of the CYP2C19 gene.

The effectiveness of Plavix will depend on conversion to an active metabolite by the cytochrome P450 (CYP) system, most principally CYP2C19.

Patients who are CYP2C19-poor metabolizers will need to get the available tests. These patients also might benefit from another platelet P2Y inhibitor.

Are there any contraindications with Plavix?

  • Active pathological bleeding, such as peptic ulcer or intracranial hemorrhage
  • Hypersensitivity to clopidogrel or any ingredient of Plavix

How long does it take Plavix to work?

Plavix begins to work within 2 hours of taking the first dose. However, it may take up to 3 to 5 days for the full effect on platelet function to be achieved. It is important to continue taking Plavix as prescribed, especially for the long-term prevention of blood clots.

What interacts with Plavix?

When Plavix is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • CYP2C19 inducers such as rifampin
  • SSRIs such as fluoxetine
  • SNRIs such as duloxetine
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen
  • Blood thinners or anticoagulants such as warfarin
  • Repaglinide
  • Proton pump inhibitors such as Prilosec (omeprazole) or Nexium (esomeprazole)

What doses of Plavix are available?

Plavix comes as a film-coated tablet with the following strengths:

  • 75 mg tablet
  • 300 mg tablet

How do I store Plavix?

Store Plavix at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Which pharmaceutical company manufactures Plavix?

Plavix is manufactured by Sanofi and Bristol-Myers Squibb.

Is there a generic version of Plavix?

There are generics available for the brand-name medication, Plavix.

How do I stop taking Plavix?

To stop taking Plavix, consult your healthcare provider, as discontinuing it abruptly can increase the risk of blood clots. Always follow your healthcare provider’s instructions to ensure a safe transition and avoid complications.

Can Plavix be used if I am pregnant?

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you. There are limited studies on the effects of clopidogrel in pregnant women, and the potential risks to the fetus are not well understood. Currently, it is not expected for Plavix to affect an unborn baby.

Can Plavix be used if I am breast feeding?

There are no published studies on the use of clopidogrel while breastfeeding. The manufacturer reports that no adverse effects have been observed in infants exposed to clopidogrel through breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Plavix from UniversalDrugstore™

What happens after I place my order for Plavix with Universal Drugstore?

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

How long does it take to process and deliver my order for Plavix?

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Can I track my order of Plavix?

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

What should I do if there is an issue with my order for Plavix?

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

How is my medication packaged to ensure privacy and safety?

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Does Universal Drugstore ship medications that require refrigeration or special handling?

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

What are the shipping costs, and does Universal Drugstore offer free delivery?

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Does Universal Drugstore accept Medicare or Medicaid for prescriptions?

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Can I use private health insurance to cover my prescription from Universal Drugstore?

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

How secure is my payment information when ordering from Universal Drugstore?

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Can I order a generic alternative to Plavix?

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

Do I need a prescription to order Plavix?

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.

Can I order multiple medications at once?

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Can I refill my prescription through Universal Drugstore?

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Does Universal Drugstore offer discounts or price matching?

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

How can I contact Universal Drugstore for additional support?

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Important

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.