Prolopa CR(Benserazide Hydrochloride/Levodopa)
Prolopa CR Drug Information
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You can easily place an order on our website in under 5 minutes. First you need to set up an account with us, create a payment method, and send us your prescriptions. Alternatively, you can order by downloading our order form or by placing an order over the phone. Delivery can take approximately 2 weeks to North America, and 4 weeks to other countries.
Prolopa CR Overview
This combination medication is used to treat symptoms of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) in the brain. Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa's side effects such as nausea and vomiting.
How to Use Prolopa CR
Take Prolopa CR by mouth with or without food as directed by your doctor, usually 2 to 3 times a day. Doses are usually taken 4 to 8 hours apart while awake. Do not crush or chew Prolopa CR. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Taking Prolopa CR with food may help to decrease nausea. It is best to avoid a high-protein diet (it decreases the amount of levodopa that your body takes in) during treatment, unless directed otherwise by your doctor. Separate your dose of Prolopa CR by as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of Prolopa CR absorbed by the body. Consult your doctor or pharmacist for more details. The Dosage of Prolopa CR is based on your medical condition and response to treatment. If you are switching from immediate-release levodopa/carbidopa to Prolopa CR, your doctor may slightly increase your dose of Prolopa CR to get the same response. Prolopa CR may take a little longer to work in the morning than the immediate-release medication because it is absorbed more slowly. Let your doctor know if this becomes a problem. Use Prolopa CR regularly to get the most benefit from it. To help you remember, take it at the same times each day. Your doctor may also prescribe immediate-release carbidopa/levodopa or carbidopa alone to be taken with Prolopa CR. Make sure you understand your dosing schedule and follow it closely. Some patients may experience a "wearing-off" (worsening of symptoms) before the next dose is due. An "on-off" effect might also occur, in which sudden short periods of stiffness occur. If these effects occur, contact your doctor for possible dose adjustments that may help to lessen this effect. Do not stop taking Prolopa CR without consulting your doctor. Some conditions may become worse when Prolopa CR is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also Side Effects section.) Tell your doctor if your condition does not improve or if it worsens.
Prolopa CR Precautions
Before taking Prolopa CR, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. Prolopa CR may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Prolopa CR, tell your doctor or pharmacist your medical history,liver disease, glaucoma, breathing problems (such as asthma), heart disease (such as heart attack, irregular heartbeat), kidney disease, stomach/intestinal ulcer, mental/mood disorders (such as depression, schizophrenia), blood disorders, seizures, sleep disorders. Prolopa CR may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). See also Side Effects section. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, Prolopa CR should be used only when clearly needed. Discuss the risks and benefits with your doctor. Levodopa passes into breast milk in small amounts and may affect how much milk you make. It is unknown if carbidopa passes into breast milk. Consult your doctor before breast-feeding.
Prolopa CR Misdose
If you miss a dose of Prolopa CR, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Prolopa CR Interactions
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.antipsychotic drugs (such as chlorpromazine, haloperidol, thioridazine), certain drugs used to treat high blood pressure (such as methyldopa). Taking MAO inhibitors with Prolopa CR may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, tranylcypromine) during treatment with Prolopa CR. Most MAO inhibitors should also not be taken for two weeks before treatment with Prolopa CR. However, certain MAO inhibitors (rasagiline, safinamide, selegiline) may be used with careful monitoring by your doctor. Ask your doctor when to start or stop taking Prolopa CR. Prolopa CR may interfere with certain laboratory tests (including urine catecholamine/glucose/ketone tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Prolopa CR.
Prolopa CR Side Effects
What are Prolopa CR side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Prolopa CR may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Prolopa CR as a result of an interaction with other medications.
Side Effects of Prolopa CR
The side effects of Prolopa CR may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Prolopa CR. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Prolopa CR may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Prolopa CR, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Prolopa CR.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Prolopa CR, or any other medication, should contact their physician. General information about Prolopa CR and the side effects associated with Prolopa CR are described in the following:
Common Prolopa CR Side Effects
- orthostatic hypotension
- symptoms of anxiety
- altered mental status
- headache disorder
Less Frequent Prolopa CR Side Effects
- acute confusion
- blurred vision
- general weakness
- muscle fasciculation
- urine discoloration
- dream disorder
- peripheral neuropathy
- peripheral edema
Rare or Very Rare Prolopa CR Side Effects
- hemolytic anemia
- cardiac arrhythmia
- duodenal ulcer
- drug-induced psychosis
- thrombocytopenic disorder
- impulse control disorder
- acute myocardial infarction
- suicidal ideation
- extrapyramidal disease
- accidental fall
- increased alanine transaminase
- increased aspartate transaminase
- bullous dermatitis
- abnormal hepatic function tests
- oculogyric crisis
- ocular hypertension
- sudden onset of sleep
- urinary retention
- gastrointestinal irritation
- increased libido
- drug-induced hot flash
- urinary incontinence
- sore throat
- memory impairment
- leg pain
- weight gain
- weight loss
- acute abdominal pain
Prolopa CR Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Prolopa CR when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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