Stalevo
Stalevo (carbidopa/levodopa/entacapone) is indicated for the treatment of Parkinson’s disease, a condition of the central nervous system (brain and spinal cord) that affects the part of your brain that controls movement. Some common side effects include involuntary movements, diarrhea, and nausea.
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Stalevo 50 Prescription Required
Stalevo 75 Prescription Required
Stalevo 100 Prescription Required
Stalevo 125 Prescription Required
Stalevo 150 Prescription Required
Stalevo 200 Prescription Required
Carbidopa/Levodopa/Entacapone 50 Prescription Required
Marketed as Syncapone 50 in India
Marketed as Sastravi in United Kingdom
Carbidopa/Levodopa/Entacapone 75 Prescription Required
Marketed as Carbidopa/Levodopa/Entacapone in United Kingdom
Carbidopa/Levodopa/Entacapone 100 Prescription Required
Marketed as Syncapone 100 in India
Carbidopa/Levodopa/Entacapone 125 Prescription Required
Marketed as Carbidopa/Levodopa/Entacapone in United Kingdom
Carbidopa/Levodopa/Entacapone 150 Prescription Required
Marketed as Syncapone in India
Carbidopa/Levodopa/Entacapone 200 Prescription Required
Marketed as Carbidopa/Levodopa/Entacapone in United Kingdom
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Important information about Stalevo
How does Stalevo work?
The active ingredients in Stalevo are carbidopa, levodopa, and entacapone. Carbidopa is a dopa decarboxylase inhibitor, levodopa is a dopamine replacement, and entacapone is a catechol-O-methyltransferase (COMT) inhibitor. In individuals with Parkinson's disease, the brain does not have enough dopamine, which makes it hard for people to move their bodies the way they want to. Levodopa helps increase the levels of dopamine in the brain, while carbidopa and entacapone block enzymes so that more levodopa can get to the brain and turn into dopamine.
How do you use Stalevo?
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Stalevo. However, the following is a synopsis of the general guidelines for the use of Stalevo:
- Take this medication exactly as directed by your physician.
- Each time you take Stalevo, take only one tablet. Taking more than one at a time increases your risk of side effects.
- You can take Stalevo with or without food. However, avoid taking it with a meal high in fat, calories, or protein. This can slow down how fast your body absorbs the medication.
What are the side effects of Stalevo?
The most common side effects of Stalevo seen in clinical trials include:
- Involuntary movements (dyskinesia).
- Abdominal pain.
- Nausea.
- Diarrhea.
- Vomiting.
- Dry mouth.
- Drowsiness.
- Changes in the color of your urine.
- Dizziness.
Some individuals may experience serious side effects while using Stalevo. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Withdrawal symptoms after treatment changes - high fevers, sweating, confusion, irregular pulse, muscle stiffness, changes in breathing.
- Rhabdomyolysis - soreness, muscle pain, and muscle cramps.
- Depression and suicidal thoughts.
- Severe allergic reaction - hives, itching, swelling, rash, and trouble breathing.
- Orthostatic hypotension - dizziness, lightheadedness, and fainting.
- Hallucinations.
- Compulsive behaviors.
- Serious eye problems - sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
- Diarrhea - dehydration, weight loss, and low potassium levels.
These are not all of the possible side effects of Stalevo. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Stalevo?
Before starting Stalevo, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:
- Mental health or behavioral problems (psychosis).
- Peptic ulcer.
- Colitis.
- Sleep problems.
- Other movement disorders.
- Eye problems.
- Neuroleptic malignant syndrome (NMS).
- Low blood pressure (hypotension).
- Hepatic (liver) problems.
- Unusual urges.
Are there any contraindications with Stalevo?
- Previous allergic reaction/hypersensitivity to levodopa, carbidopa, or entacapone, or any of the other ingredients of Stalevo.
- Narrow-angle glaucoma.
- Currently taking a nonselective monoamine oxidase inhibitor (MAOI).
How long does it take Stalevo to work?
Stalevo starts to work about 30 minutes after your first dose.
What interacts with Stalevo?
When Stalevo is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Nonselective MAO inhibitor (monoamine oxidase inhibitor) within the past 2 weeks (phenelzine, tranylcypromine).
- Epinephrine.
- Methyldopa.
- Apomorphine.
- Tricyclic antidepressant (amitriptyline, nortriptyline).
- Antipsychotic medication.
- Isoniazid or rifampin.
- Phenytoin.
- Papaverine.
- Iron supplements or other products (multivitamins) containing iron.
- Probenecid.
- Bile acid sequestrant (cholestyramine).
- Erythromycin.
- Other medication that causes dizziness and sleepiness (prescription pain medicines, sleep medicines, medicines for anxiety).
- Other medications containing carbidopa or levodopa.
What doses of Stalevo are available?
Stalevo tablets are film-coated and come in the following strengths:
- Stalevo 50:12.5 mg of carbidopa, 50 mg of levodopa and 200 mg of entacapone.
- Stalevo 75: 18.75 mg of carbidopa, 75 mg of levodopa and 200 mg of entacapone.
- Stalevo 100: 25 mg of carbidopa, 100 mg of levodopa and 200 mg of entacapone.
- Stalevo125: 31.25 mg of carbidopa, 125 mg of levodopa and 200 mg of entacapone.
- Stalevo 150: 37.5 mg of carbidopa, 150 mg of levodopa and 200 mg of entacapone.
- Stalevo 200: 50 mg of carbidopa, 200 mg of levodopa and 200 mg of entacapone.
How do I store Stalevo?
Store this medication at room temperature and keep it out of reach of children.
Which pharmaceutical company manufactures Stalevo?
Orion Corporation is the pharmaceutical company that manufactures Stalevo.
Is there a generic version of Stalevo?
There are no lower-cost generics available for the brand-name Stalevo.
How do I stop taking Stalevo?
Do not stop or adjust your use of this medication without first consulting with your doctor. It may be necessary to reduce the dose of Stalevo gradually to prevent side effects and the effects of the medication from “wearing off” and keep the symptoms of Parkinson's disease from worsening.
Can Stalevo be used if I am pregnant?
It is unknown if or how Stalevo could affect pregnancy or harm an unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
Can Stalevo be used if I am breast feeding?
Levodopa, one of the medicines in carbidopa/levodopa/entacapone, is known to pass into breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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What happens after I place my order for Stalevo with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Stalevo?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Stalevo?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Stalevo?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
How is my medication packaged to ensure privacy and safety?
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Does Universal Drugstore ship medications that require refrigeration or special handling?
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
What are the shipping costs, and does Universal Drugstore offer free delivery?
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Does Universal Drugstore accept Medicare or Medicaid for prescriptions?
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Can I use private health insurance to cover my prescription from Universal Drugstore?
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
How secure is my payment information when ordering from Universal Drugstore?
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Can I order a generic alternative to Stalevo?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Stalevo?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Does Universal Drugstore offer discounts or price matching?
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
How can I contact Universal Drugstore for additional support?
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.