Cholesterol is a waxy substance found in all the cells of the body. While the body produces it naturally, it is also present in some foods. Cholesterol travels through the body via the arteries, in small packages made of fats and protein.

It’s necessary for healthy heart function, however high levels of the so-called bad cholesterol – triglycerides and low-density lipoprotein (LDL) – and low levels of good cholesterol, known as high-density lipoprotein (HDL), increase the risk of heart attacks and strokes.

Marketed Internationally as Inegy

In some countries, Vytorin is sold under the brand name Inegy.

Vytorin Active Ingredient

Generic Vytorin Alternative: Ezetimibe-Simvastatin

Vytorin is a combination of two active ingredients: ezetimibe and simvastatin. When coupled with diet and lifestyle changes, this medication helps to reduce levels of bad cholesterol and increase levels of good cholesterol.

Patients have a choice of buying brand name Vytorin or generic alternatives. A number of safe, affordable generic alternatives to Vytorin are available through our international online pharmacy.

General Drug Information

What is Vytorin and What Is It Used For?

Vytorin is a combination medication consisting of two substances, ezetimibe, and simvastatin. Ezetimibe reduces the amount of cholesterol the body absorbs from the diet, while simvastatin reduces the amount of cholesterol produced by the liver. When coupled with a proper diet, this medication can help to reduce levels of bad cholesterol and increase levels of good cholesterol. This lessens the risk of heart disease, heart attack, and stroke.

Lifestyle changes such as regular exercise, giving up smoking and losing weight enhance the effects of this medication in helping patients prevent heart disease.

Warnings

The information on this page is not a replacement for a consultation with a physician, qualified to treat this condition and prescribe medication. The information is supplied by a third party, independent from this website and only serves to raise awareness about this condition and point out basic information regarding treatment.

The website cannot take responsibility for the reliability or medical efficacy of the information provided. As mentioned above, patients should seek medical attention to ensure effective and safe treatment.

Not all products are shipped by our contracted Canadian pharmacy. The source country, shipping country or drug manufacturer may vary depending on availability.

The website also maintains commercial ties with dispensaries around the world. Products can be sourced from a number of countries. Patients should note that different items within an order can be shipped from different jurisdictions, depending on availability and cost at the time an order was placed.

Usage and Application

Vytorin and its generic alternatives should be taken exactly as prescribed by a patient’s doctor, and the dosage depends on the patient’s condition, age, response to treatment and other medications they may be taking. Patients should discuss the full list of prescription medications and supplements they are taking with their doctor before starting treatment with Vytorin.

Most patients are prescribed one daily oral dose to be taken with or without food, usually in the evening. The usual maximum dose is 10/40mg per day. Patients who have been prescribed more should discuss the heightened risk involved with taking elevated doses with their doctor. Patients should not increase their dose without consulting their physician first.

Some patients taking vitamin B3, which is also known as niacin, may need to take lower doses of simvastatin.

It is necessary to use Vytorin regularly in order to experience its full benefit. To reduce the risk of forgetting, patients are advised to take the medication at the same time each day. It may take two to four weeks for people to experience the full benefit of this medication. The therapy should continue even if people feel well.

All patients should avoid eating grapefruit or drink grapefruit juice as it increases blood levels of Vytorin.

People who take other cholesterol-reducing drugs – such as cholestyramine or colestipol – should exercise caution. Vytorin should be taken at least two hours before or at least four hours after taking these medications. If mixed, these medications interact with Vytorin, preventing its full absorption.

Diet and exercise are also important parts of any treatment regime.

Considerations Before Taking Vytorin

Before starting treatment patients need to discuss the possibility of allergic reactions to Vytorin or its main ingredients.

It is vital to discuss the patient’s medical history, especially any history of alcohol abuse, liver disease, and kidney disease.

Patients taking this medication should limit alcohol consumption as daily use may cause liver problems.

Patients preparing for surgery or certain dental procedures should inform their doctor or dentist about all medicines, supplements and herbal products they are taking.

Older adults may be more sensitive to the adverse side effects of this medication, especially muscle problems.

Simvastatin, one of the two active ingredients in this medication, may harm an unborn baby. Therefore, Vytorin is not safe for use during pregnancy. Female patients on this medication need to discuss reliable birth control methods with their doctor, and those who suspect pregnancy need to tell their doctor right away.

It is not known whether Vytorin passes into breast milk, however, similar drugs do. This medication is not recommended for use by nursing mothers.

Delayed and Omitted Doses

Patients who miss a dose of Vytorin should take it as soon as they remember. If this happens near the time of the next dose, patients should skip the missed dose and proceed as usual. Patients should not double up the dose in order to catch up.

Other Medications and Vytorin

Drug interactions may change the way Vytorin (and its generic alternatives) works, increasing the risk of side effects. Before starting treatment, patients need to discuss the full list of medications and supplements they are taking with their doctor. Patients should not change their dose or stop taking this medication unless their physician advises them to do so.

Some blood thinning medications – such as Coudamin – may interact negatively with Vytorin. This is also the case with cyclosporine, prescribed to treat organ rejection, the gout medicine colchicine, and gemfibrozil – a cholesterol drug. Danocrin, prescribed to treat endometriosis, should also be avoided.

Patients should avoid drugs which affect the removal of simvastatin from the body. This is the case with antifungals such as itraconazole, ketoconazole, posaconazole, and voriconazole. The list also includes hepatitis C medications boceprevir and telaprevir, as well as cobicistat, which is prescribed to prevent heart attack or stroke.

Also affecting the removal of simvastatin from the body are macrolide antibiotics such as clarithromycin and erythromycin and the antibiotic telithromycin. Patients should also exercise caution if they are taking the antidepressant nefazodone, as well as certain HIV medications, including delavirdine, nelfinavir, and ritonavir.

Some red yeast rice products naturally contain the statin lovastatin and should be avoided in order to prevent potential muscle and liver problems.

Adverse Reactions

Most patients are able to use Vytorin safely and without serious negative side effects.

The medication can cause mild memory problems or confusion in some patients.

In rare cases, statins such as simvastatin can worsen diabetes.

Patients should monitor for liver problems. They should immediately contact their treating physician in the event of symptoms such as yellowing of the eyes and skin, dark urine, severe stomach pain or persistent vomiting.

Vytorin may cause muscle problems and, in rare cases, can lead to serious conditions such as rhabdomyolysis and autoimmune myopathy. Patients should monitor for symptoms such as muscle pain and weakness, fever, and changes in the amount of urine.

Serious allergic reactions to Vytorin are rare, yet patients should be aware of allergic reactions including itching and swelling, severe dizziness and trouble breathing.

How to Store Vytorin

Vytorin should be stored at room temperature, away from light or moisture. Do not store in the bathroom. Keep away from children and pets.

Unwanted medication should be disposed of properly and should not be poured into drains or flushed down the toilet. Patients should consult a pharmacist or their local waste disposal company to find out more about safe disposal methods.

Vytorin Coupon

Although Vytorin coupons are available with other online pharmacies, customers will find that UDS prices are often much lower.

Vytorin Drug Information

Vytorin Overview

This combination medication is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Simvastatin belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Vytorin work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details. Lowering "bad" cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.
How to Use Vytorin

Read the Patient Information Leaflet if available from your pharmacist before you start taking and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Vytorin by mouth with or without food as directed by your doctor, usually once daily in the evening. The Dosage of Vytorin is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). The usual maximum dose for the simvastatin in Vytorin is 40 milligrams a day. If you have been instructed by your doctor to take more than 40 milligrams of simvastatin, continue on that same dose. However, promptly talk with him or her about the risks and benefits of your higher dose. Do not increase your dose or take Vytorin more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased. Avoid eating grapefruit or drinking grapefruit juice while using Vytorin unless your doctor instructs you otherwise. Grapefruit can increase the amount of Vytorin in your bloodstream. Consult your doctor or pharmacist for more details. If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take at least 2 hours before or at least 4 hours after taking these medications. These medications can react with , preventing its full absorption. Take Vytorin regularly in order to get the most benefit from it. Remember to take it at the same time each day. It is important to continue taking Vytorin even if you feel well. Most people with high cholesterol or triglycerides do not feel sick. It is very important to continue to follow your doctor's advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of Vytorin.
Vytorin Precautions

Before taking , tell your doctor or pharmacist if you are allergic to ezetimibe or simvastatin; or if you have any other allergies. may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Vytorin, tell your doctor or pharmacist your medical history,liver disease, kidney disease, alcohol use. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Limit alcoholic beverages. Daily use of alcohol may increase your risk for liver problems, especially when combined with . Ask your doctor or pharmacist for more information. Older adults may be more sensitive to the side effects of Vytorin, especially muscle problems. Vytorin must not be used during pregnancy. Simvastatin may harm an unborn baby. Therefore, it is important to prevent pregnancy while taking Vytorin. Consult your doctor for more details and to discuss the use of reliable forms of birth control (such as condoms, birth control pills) while taking Vytorin. If you become pregnant or think you may be pregnant, tell your doctor right away. It is unknown if Vytorin passes into breast milk. However, similar drugs pass into breast milk. Breast-feeding while using Vytorin is not recommended. Consult your doctor before breast-feeding.
Vytorin Misdose

If you miss a dose of Vytorin, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Vytorin Interactions

See also How To Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval."blood thinners" (such as warfarin), cyclosporine, danazol, gemfibrozil. Other medications can affect the removal of simvastatin from your body, which may affect how simvastatin works. Examples include certain azole antifungals (such as itraconazole, ketoconazole, posaconazole, voriconazole), boceprevir, cobicistat, colchicine, delavirdine, macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, HIV protease inhibitors (such as nelfinavir, ritonavir), telaprevir, telithromycin, among others. Chinese people should not take niacin at doses used to lower cholesterol (1 gram or more) when taking Vytorin. Doing so may increase the risk of side effects (especially muscle problems). Talk with your doctor for details. Do not take any red yeast rice products while you are taking ezetimibe/simvastatin because some red yeast rice products may also contain a statin called lovastatin. Taking ezetimibe/simvastatin and red yeast rice products together can increase your risk of serious muscle and liver problems.
Vytorin Side Effects

Remember that your doctor has prescribed Vytorin because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Vytorin do not have serious side effects. A very small number of people taking simvastatin may have mild memory problems or confusion. If these rare effects occur, talk to your doctor. Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks. Vytorin may rarely cause muscle problems (which can rarely lead to very serious conditions called rhabdomyolysis and autoimmune myopathy). Females, older adults, and Chinese people may be at higher risk.muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine). Vytorin may rarely cause liver problems. If you notice any of the following rare but serious side effects,yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting. A very serious allergic reaction to Vytorin is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
List of Vytorin side effects
Vytorin Storage

Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.

Vytorin

What is a generic medication?

Related Products

Vytorin Helps Treat the Following Conditions:

High Cholesterol

Marketed Internationally as Inegy

Vytorin Active Ingredient

Generic Vytorin Alternative: Ezetimibe-Simvastatin

General Drug Information

What is Vytorin and What Is It Used For?

Warnings

Usage and Application

Considerations Before Taking Vytorin

Delayed and Omitted Doses

Other Medications and Vytorin

Adverse Reactions

How to Store Vytorin

Vytorin Coupon

Vytorin Drug Information

Vytorin Overview

How to Use Vytorin

Vytorin Precautions

Vytorin Misdose

Vytorin Interactions

Vytorin Side Effects

Vytorin Storage