Buy Ziana Gel Online (Clindamycin Phosphate/Tretinoin)
What is Ziana Gel?
What is Ziana Gel?
Brand-name Ziana gel (generic names clindamycin phosphate and tretinoin) is a prescription topical gel used in healthcare. It is indicated for the topical treatment of acne vulgaris in patients 12 years of age and older. Some common side effects are dry skin, skin irritation, and redness.
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Purchase Ziana Gel from Universal Drugstore today and save!
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- All Strength's
- 1.2%/0.025%
Ziana Gel brand
Ziana 1.2%/0.025%
Prescription RequiredProduct of Canada
Marketed as Biacna Topical Gel in Canada.
Clindamycin Phosphate/Tretinoin (generic Ziana Gel)
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Important information about Ziana Gel
Ziana gel is a combination of two medications that treat acne vulgaris. Clindamycin is an antibiotic that helps kill acne-causing bacteria on the skin, while tretinoin is a retinoid related to vitamin A that promotes healthy skin growth and helps reduce the amount of oil on the skin.
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Ziana gel. However, the following is a synopsis of the general guidelines for the use of Ziana gel:
- It is not for oral, ophthalmic, or intravaginal use.
- Apply a pea-sized amount once daily at bedtime to the entire face. Dot it onto the chin, cheeks, nose, and forehead, then gently rub it in. Keep it away from the eyes, mouth, angles of the nose, and other mucous membranes.
- Do not apply Ziana gel to sunburned skin. Avoid sunlamps and limit sun exposure while using tretinoin. Daily sunscreen and protective clothing are recommended.
- Avoid using medicated or strong soaps and cleansers, or those with a strong drying effect (those containing alcohol, astringents, spices, or lime), as these may increase skin irritation.
Some mild or common side effects of Ziana gel seen in clinical trials as compared to placebo include:
- Dry skin, scaling, itching, burning, and stinging.
- Temporary change in skin colour.
Some individuals may experience serious side effects while using Ziana gel. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Signs of colitis, such as watery or bloody stools and stomach cramps.
- Severe skin reactions such as redness, hives, swelling, or blisters.
- Signs of an allergic reaction, such as trouble breathing, chest pain, hives, or anaphylaxis.
These are not all of the possible side effects of Ziana gel. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
Before starting Ziana gel, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:
Pregnancy or breastfeeding.
History of ulcerative colitis, regional enteritis, Crohn’s disease, or antibiotic-associated colitis.
It can take up to 12 weeks to work, but your acne may worsen in the first few weeks of using it, which is normal.
When Ziana gel is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Medicated or abrasive soaps and cleansers, skin products with a strong drying effect, and products with high concentrations of alcohol, astringents, spices, or lime. These can increase skin irritation.
- Erythromycin-containing products should not be used with Ziana gel because they may counteract the effects of clindamycin.
- Neuromuscular blocking agents, as clindamycin may enhance the effect of these medicines, so caution is advised.
Ziana gel is available as a topical gel containing clindamycin phosphate 1.2% and tretinoin 0.025%.
It should be stored at room temperature, out of the reach of children and pets.
It is manufactured by Contract Pharmaceuticals for Medicis.
Yes, it is available from many manufacturers of generic drugs.
If allergy, severe diarrhea, or signs of colitis happen, stop using Ziana gel and contact your healthcare provider right away. For other concerns, get medical advice before stopping treatment.
Because topical tretinoin has caused fetal deformities when pregnant people used it, other agents are preferred in pregnant people.
Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
It is not known whether tretinoin and clindamycin are excreted into breast milk following topical administration.
Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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Click to joinImportant information about buying Ziana Gel from UniversalDrugstore™
We ship to destinations within the United States, including Alaska and Hawaii, as well as internationally. Delivery typically takes about 2 weeks for orders shipped within the U.S. and Canada, and about 4 weeks for international orders, depending on your location and customs processing.
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
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Medical Disclaimer
The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Jamie Winn, PharmD, is a licensed pharmacist and seasoned medical content reviewer with over 20 years of experience in clinical pharmacy, patient care, and healthcare leadership.
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Shirley is a Medical Writer and first-year Doctor of Pharmacy (PharmD) student at the University of Alberta, where she is building on her strong foundation in health sciences and patient care.
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