Benzaclin Gel

The active ingredients in BenzaClin Gel are benzoyl peroxide and clindamycin phosphate.

These ingredients work together to target acne in two ways:

• Benzoyl peroxide helps break down clogged pores, reduces oil buildup, and kills bacteria on the skin.
• Clindamycin is an antibiotic that slows the growth of acne-causing bacteria and reduces inflammation.

The combination makes BenzaClin helpful for treating both inflamed pimples and whiteheads or blackheads.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using BenzaClin. However, the following is a synopsis of the general guidelines for the use of BenzaClin:

• Wash your hands before and after applying the gel.
• Gently clean the affected areas using a mild cleanser and warm water, then pat dry.
• Apply a thin layer of the gel to acne-affected skin, usually once or twice a day.
• Avoid the eyes, mouth, nose, and all mucous membranes.
• Allow the gel to fully absorb before applying cosmetics, sunscreen, or other skincare products.
• Do not use sunlamps or tanning beds. Benzoyl peroxide may increase sun sensitivity.
• If skin becomes too dry or irritated, your healthcare provider may adjust how often you apply the gel.
• If you miss a dose, apply it as soon as you remember, unless it is close to the next scheduled dose.

Some mild or common side effects of BenzaClin seen in clinical trials as compared to placebo include:

• Dryness or peeling of the skin.
• Mild redness (erythema).
• Burning or stinging sensation.
• Irritation at the application site.
• Itching.
• Increased sun sensitivity.
• Oiliness or tightness of the skin.

Some individuals may experience serious side effects while using BenzaClin. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reactions such as hives, swelling, or trouble breathing.
• Severe diarrhea or watery stools may indicate antibiotic-associated colitis.
• Persistent abdominal pain.
• Rash or blistering.
• Severe skin irritation that does not improve.
• Signs of ulcerative colitis or flare-ups in people with digestive conditions.

These are not all of the possible side effects of BenzaClin. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting BenzaClin, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• A history of gastrointestinal disorders such as ulcerative colitis or regional enteritis.
• A history of antibiotic-associated colitis.
• Sensitive skin or a history of contact dermatitis.
• A tendency to sunburn.
• Known allergies to benzoyl peroxide, clindamycin, or lincomycin.
• Skin conditions that weaken the protective barrier.
• Tell your healthcare provider about all skincare products or acne medications you use, especially those containing retinoids, salicylic acid, sulfur, or other drying agents. Using too many acne products at once may increase irritation.

• Avoid sun exposure, and use sunscreen daily while using BenzaClin Gel.

BenzaClin Gel should not be used in individuals who:

• Are allergic to clindamycin, lincomycin, or benzoyl peroxide.
• Have a history of severe colitis linked to antibiotic use.
• Have certain digestive conditions that could worsen with clindamycin exposure.
• Your healthcare provider will decide if BenzaClin is appropriate based on your medical history.

Many users begin noticing improvement within 2 to 6 weeks, with clearer results after 8 to 12 weeks of consistent use.

Because acne varies from person to person, your healthcare provider may adjust your treatment plan depending on how your skin responds.

When BenzaClin is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Other topical acne products (retinoids, salicylic acid, sulfur, resorcinol).
• Skin-peeling or drying agents.
• Products containing alcohol or strong astringents.
• Erythromycin or products containing erythromycin.
• Medications for dermatitis or eczema.
• Sun-sensitizing medications.
• Supplements that irritate the skin or make it more sensitive.
• Avoid using BenzaClin Gel at the same time as other topical antibiotics unless your healthcare provider instructs you to.

BenzaClin Gel is available in the following formulation:

• Benzoyl peroxide 5% / clindamycin phosphate 1% topical gel

It is supplied in tubes or pump dispensers, depending on the manufacturer.

Store at room temperature and keep out of reach of children.

BenzaClin is manufactured by Bausch Health (formerly Valeant Pharmaceuticals), though other companies may produce authorized generics.

Yes. Generic versions containing benzoyl peroxide and clindamycin phosphate are available. Formulations may vary slightly depending on the manufacturer, but they contain the same active ingredients.

Do not stop using BenzaClin Gel without consulting your healthcare provider. If you experience severe irritation, diarrhea, or allergic symptoms, stop using the gel and seek medical advice right away.

If your acne clears, your provider may reduce how often you apply the medication or switch you to a long-term maintenance therapy.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. It is unknown how much topical clindamycin passes into breast milk, so caution is advised. Avoid applying the medication to areas that may come into contact with your infant’s skin.