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Buy Isoptin SR Online
(Verapamil Hydrochloride ER)

What is Isoptin SR?

What is Isoptin SR?

Calan Sr is indicated for the treatment of lowering high blood pressure (hypertension), preventing angina (chest pain), preventing paroxysmal supraventricular tachycardia, and helping to keep a normal heart rhythm in people who have atrial fibrillation.

Order Isoptin SR online today and save!

Purchase Isoptin SR from Universal Drugstore today and save!

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  • All Strength's
  • 120mg
  • 180mg
  • 240mg
  • 360mg

Isoptin SR brand

Calan SR 
240mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Securon SR in United Kingdom.

Isoptin SR 
120mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Half Securon SR in United Kingdom.

Isoptin SR 
240mg

Prescription Required
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Prescription Required
Product of India

Product of India

Marketed as Calaptin SR in India.

Also available from Turkey
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Prescription Required
Product of Turkey

Product of Turkey

Marketed as Isoptin SR in Turkey

Verapamil Hydrochloride ER (generic Isoptin SR)

What are generics?

Verapamil Hydrochloride ER 
120mg

Prescription Required
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Prescription Required
Product of United States

Product of United States

Also available from Canada
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Prescription Required
Product of Canada

Product of Canada

Verapamil Hydrochloride ER 
180mg

Prescription Required
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Prescription Required
Product of United States

Product of United States

Verapamil Hydrochloride ER 
240mg

Prescription Required
Select Quantity
Prescription Required
Product of United States

Product of United States

Verapamil Hydrochloride ER 
360mg

Prescription Required
Select Quantity
Prescription Required
Product of United States

Product of United States

Marketed as Verapamil Hydrochloroide ER in United States.

Verapamil Hydrochloride SR (generic Isoptin SR)

What are generics?

Verapamil Hydrochloride SR 
240mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Verapamil Hydrochloroide MR in United Kingdom.

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Important information about Isoptin SR

The active ingredient in Calan SR is verapamil ER 24 HR. This medication belongs to two drug classes, including calcium channel blockers and group IV antiarrhythmics. Its mechanism of action works by relaxing the blood vessels to keep heart rhythms normal and decreases the amount of work the heart has to do.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Calan SR. However, the following is a synopsis of the general guidelines for the use of Calan SR:

  • Take this medication orally exactly as directed by your healthcare provider at the same time daily.
  • Swallow the capsules whole or open the capsule and put the contents in 1 teaspoon of applesauce.
  • Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.

Some mild or common side effects of Calan SR seen in clinical trials as compared to placebo include:

  • Constipation.
  • Headache.
  • Dizziness.
  • Abnormal liver function tests.

Some individuals may experience serious side effects while using Calan SR. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Severe allergic reactions - skin rash, itching, hives, swelling.
  • Heart failure - shortness of breath, sudden weight gain.
  • Slow heart rate - dizziness, feeling lightheaded, unusual weakness.
  • Liver injury - right upper belly pain, loss of appetite, nausea, yellowing skin or eyes.
  • Low blood pressure (hypotension) - dizziness, blurry vision.

These are not all of the possible side effects of Calan SR. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Calan SR, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

  • Duchenne muscular dystrophy
  • Heart disease (congestive heart failure, irregular heart rhythm).
  • Pulmonary edema (fluid in the lungs).
  • Liver disease.
  • Low blood pressure (hypotension).
  • Kidney disease.
  • Nerve-muscle disorder (myasthenia gravis, muscular dystrophy).

Boxed Warning

  • Heart failure.
  • Hypotension.
  • Elevated liver enzymes.
  • Accessory bypass tract (Wolff-Parkinson-White or Lown-Ganong-Levine).
  • AV block.

  • Severe left ventricular dysfunction.
  • Hypotension or cardiogenic shock.
  • Sick sinus syndrome.
  • Second- or third-degree heart block or AV block (except in patients with a functioning artificial ventricular pacemaker).
  • Patients with atrial flutter or atrial fibrillation and an accessory bypass tract (eg, Wolff-Parkinson-White, Lown-Ganong-Levine syndromes).
  • Previous hypersensitivity/allergic reaction to verapamil hydrochloride.

Calan SR starts to work on the day you start taking it, but it may take a couple of weeks to work fully.

When Calan SR is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Grapefruit juice.
  • Lithium.
  • Other heart or blood pressure medications (clonidine, digoxin, ivabradine, quinidine).
  • Medications for tuberculosis (rifampin).
  • Beta blocker (atenolol, metoprolol, propranolol).
  • Medications for seizures (carbamazepine, phenobarbital).
  • Cholesterol-lowering medications (atorvastatin).
  • Antiviral medications for hepatitis or HIV/AIDS (atazanavir).
  • Disopyramide.
  • Dofetilide.
  • Theophylline.
  • Antifungal medications.
  • Aspirin.
  • St. John’s wort.
  • Antibiotic (clarithromycin).
  • Cimetidine.
  • Cyclosporine.

Calan Sr is available in a variety of dosage forms, including:

  • Extended-release oral capsules: 100 mg, 120 mg, 180 mg, 200 mg, 240 mg, 300 mg, 360 mg.
  • Extended-release tablets: 120 mg, 180 mg, 240 mg.
  • Oral tablets: 40 mg, 80 mg, 120 mg.

Store this medication at room temperature and keep it out of the reach of children.

Pfizer is the pharmaceutical company that manufactures Calan SR. Other names of this medication include Covera-HS, Isoptin SR, and Verelan PM.

There are lower-cost generic options available for the brand-name Calan SR.

Do not stop or adjust your use of this medication without first consulting with your healthcare provider.

It is unknown whether Calan SR will harm an unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Verapamil is known to pass into breast milk and may cause side effects in the nursing baby. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Isoptin SR from UniversalDrugstore™

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

Medical Disclaimer

The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.