Coreg CR
Brand name Coreg CR is an alpha- and beta-blocker indicated for the treatment of mild to severe heart failure, left ventricular dysfunction following a myocardial infarction (heart attack), and high blood pressure (hypertension).
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Carvedilol CR Prescription Required
Marketed as Cardivas CR in India
Carvedilol CR Prescription Required
Marketed as Cardivas CR in India
Carvedilol CR Prescription Required
Marketed as Cardivas CR in India
Carvedilol CR Prescription Required
Currently Unavailable
Marketed as Carca CR in India
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Important information about Coreg CR
How does Coreg CR work?
The active ingredient in Coreg CR is carvedilol phosphate. Its mechanism of action is as an alpha and beta-adrenergic receptor antagonist (alpha-blocker and beta-blocker). It works by relaxing blood vessel walls, lowering blood pressure, and reducing heart rate.
How do you use Coreg CR?
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Coreg CR. However, the following is a synopsis of the general guidelines for the use of Coreg CR:
- This medication should always be taken with food to slow its absorption and reduce the side effects of low blood pressure (orthostatic hypotension).
- The extended-release capsules can be opened and sprinkled into applesauce if you have trouble swallowing. They should otherwise not be crushed or chewed.
- Those with diabetes should monitor their blood sugar levels more regularly, as this medication can mask the symptoms of low blood sugar (hypoglycemia).
- Until you know how this medication affects you, avoid driving a car or operating heavy machinery, in case you experience dizziness.
What are the side effects of Coreg CR?
The most common side effects of Coreg CR include:
- Slow heartbeat (bradycardia).
- Dizziness, lightheadedness, or orthostatic hypotension.
- Swelling in the legs (peripheral edema).
- Insomnia.
- Diarrhea.
- Increased blood sugar levels (hyperglycemia).
Some individuals may experience serious side effects while using Coreg CR. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Severe allergic reaction presenting with swelling of the face, lips, tongue, or throat, and trouble breathing.
- Worsening heart failure (heart failure exacerbation) symptoms include shortness of breath, chest pain (angina), rapid weight gain, fatigue, and fluid retention (swelling in the legs).
- Acute bronchospasm, which would feel like chest tightness, shortness of breath, cough, lightheadedness, and extreme fatigue.
These are not all of the possible side effects of Coreg CR. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Coreg CR?
Before starting Coreg CR, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:
- Bronchial asthma or related bronchospastic conditions.
- Heart block.
- Sick sinus syndrome.
- Severe bradycardia or low resting heart rate (unless you have a permanent pacemaker).
- Cardiogenic shock or decompensated heart failure.
- Severe liver disease.
- History of serious hypersensitivity reaction to any component of this medication or other medications containing carvedilol.
- Peripheral vascular disease.
- Thyroid disorders, including hyperthyroidism.
- Pheochromocytoma.
- Prinzmetal’s variant angina.
- Coronary artery disease.
- An upcoming surgery, including cataract surgery, puts you at a higher risk of Intraoperative Floppy Iris Syndrome when you take carvedilol.
Are there any contraindications with Coreg CR?
- Low resting heart rate (bradycardia).
- Asthma or bronchospasm from chronic bronchitis or emphysema.
- Second- or third-degree AV block.
- Sick sinus syndrome.
- Cardiogenic shock or decompensated heart failure.
- Severe hepatic impairment.
How long does it take Coreg CR to work?
The effects of carvedilol begin after your first dose, but it may take a few weeks before you notice a lower blood pressure.
What interacts with Coreg CR?
When Coreg CR is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- CYP2D6 inhibitors, including quinidine, fluoxetine, paroxetine, and propafenone, may increase the side effects of carvedilol when used together.
- Hypotensive medications such as clonidine can increase the risk of hypotension and bradycardia when used with carvedilol.
- Cyclosporine and digoxin levels may increase when carvedilol is taken at the same time.
- Rifampin may reduce levels of carvedilol in the blood.
- Cimetidine may increase levels of carvedilol in the blood.
- CYP2C9 inhibitors such as amiodarone or fluconazole may increase levels of carvedilol and increase the side effects of bradycardia and hypotension.
- Calcium channel blockers such as diltiazem or verapamil may lead to heart conduction problems when used with carvedilol.
- Carvedilol may increase the blood sugar reduction of insulin or other medications used for diabetes.
What doses of Coreg CR are available?
It is available in two dosage forms:
- Extended-release capsules (Coreg CR), are taken once daily in doses of 10mg, 20mg, 40mg, and 80mg.
- Immediate-release carvedilol is also available, in doses of 3.125mg, 6.25mg, 12.5mg, and 25mg taken twice daily.
How do I store Coreg CR?
It should be stored at room temperature out of the reach of children or pets.
Which pharmaceutical company manufactures Coreg CR?
It is manufactured by Waylis Therapeutics.
Is there a generic version of Coreg CR?
Yes, there is a generic version.
How do I stop taking Coreg CR?
Coreg CR should not be stopped suddenly, due to the risk of severe angina (chest pain), heart attacks, and arrhythmias. It needs to be tapered off slowly under the advice of a physician.
Can Coreg CR be used if I am pregnant?
Studies show that exposure to beta-blockers during pregnancy may increase the risk of adverse events in a newborn. For gestational hypertension, carvedilol is not the agent of choice, unless the parent also has heart failure, in which case it may be recommended. If the use of carvedilol is indicated, newborns should be monitored for bradycardia, hypoglycemia, and respiratory depression.
Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
Can Coreg CR be used if I am breast feeding?
It is unknown whether carvedilol is present in breast milk, but the use of other beta-blockers during lactation is preferred.
Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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What happens after I place my order for Coreg-cr with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Coreg-cr?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Coreg-cr?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Coreg-cr?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
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Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
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Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
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Can I order a generic alternative to Coreg-cr?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Coreg-cr?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
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