Dapsone

The active ingredient in Dapsone is dapsone, which is a sulfone drug. Its mechanism of action is that it works by inhibiting the synthesis of folic acid and is an inhibitor for specific enzymes that regulate inflammation. Overall, it is an antibacterial agent and an anti-inflammatory.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Dapsone. However, the following is a synopsis of the general guidelines for the use of Dapsone:

• This medication can be taken with or without food. It is typically taken once per day.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose.

The most common side effects of Dapsone include:

• Hemolysis (breakdown of red blood cells)
• Dizziness
• Blurred vision
• Ringing in the ears
• Stomach pain
• Nausea
• Vomiting

Some individuals may experience serious side effects while using Dapsone. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reaction: skin rash, hives, and shortness of breath
• Peripheral neuropathy: tingling, burning, numbness, pain, or weakness in your arms, hands, legs, or feet
• Hepatitis and liver damage: fever, loss of appetite, and jaundice
• Blood disorders: hemolytic anemia, agranulocytosis, low platelet counts

These are not all of the possible side effects of Dapsone. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Dapsone, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Heart disease
• Liver disease
• Anemia
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency
• Methemoglobinemia
• An infection

• Known allergy to Dapsone or any of its inactive ingredients
• Known allergy to medications in the same medication class

This medication works within 1 - 2 weeks, but full effects can take several months.

When Dapsone is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Trimethoprim
• Rifampin
• Methotrexate
• Pyrimethamine
• Antifolate medications

The dosage forms of this medication include dapsone gel and oral tablets. The oral tablets are available in 25 mg and 100 mg strengths.

Dapsone should be stored at room temperature and out of the reach of children.

There are several pharmaceutical companies that produce Dapsone.

The brand name, Aczone, has been discontinued. There are several generic versions of this medication available.

You should not stop taking this medication or change your dose without talking to your doctor first. Stopping it suddenly could lead to a worsening of your condition.

It is unknown if Dapsone can cause harm to the unborn child. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Dapsone passes into the breast milk and can affect the baby. It is not generally recommended to take this medication if you are breastfeeding. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed.