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Buy Mellaril Online
(Thioridazine Hydrochloride)

What is Mellaril?

What is Mellaril?

Mellaril (thioridazine HCl) is a prescription antipsychotic medication belonging to the phenothiazines class. It is indicated for the treatment of schizophrenia in patients who do not respond adequately to other antipsychotic medications. Some common side effects are drowsiness, dry mouth, and constipation.

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Purchase Mellaril from Universal Drugstore today and save!

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  • All Strength's
  • 10mg
  • 25mg
  • 50mg

brand Versions

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Please see generic options below.

Thioridazine Hydrochloride (generic Mellaril)

What are generics?

Thioridazine Hydrochloride 
10mg

Prescription Required
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Prescription Required
Product of India

Product of India

Marketed as Thioril in India.

Thioridazine Hydrochloride 
25mg

Prescription Required
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Prescription Required
Product of India

Product of India

Marketed as Thioril in India.

Thioridazine Hydrochloride 
50mg

Prescription Required
Select Quantity
Prescription Required
Product of India

Product of India

Marketed as Thioril in India.

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Important information about Mellaril

The active ingredient in Mellaril is thioridazine HCl. Thioridazine is an antipsychotic medication that affects dopamine and other neurotransmitters in the brain. These effects may help reduce symptoms of schizophrenia, including hallucinations, delusions, disorganized thinking, and agitation.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Mellaril. However, the following is a synopsis of the general guidelines for the use of Mellaril:

  • Take Mellaril exactly as prescribed by your healthcare provider.
  • Mellaril is taken by mouth, usually in divided doses.
  • Your doctor will determine the lowest effective dose for your condition.
  • Do not change your dose or stop treatment without consulting your healthcare professional.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once.
  • You should receive an electrocardiogram of your heart before taking this medication, and periodically while you are on it.
  • This medication can make you drowsy, so don't plan to drive or operate any heavy machinery until you know how it affects you.

Some mild or common side effects of Mellaril include:

  • Sedation.
  • Dry mouth.
  • Constipation.
  • Blurred vision.
  • Weight gain.
  • Restlessness.
  • Dizziness when standing up (orthostatic hypotension).
  • Sensitivity to light (photosensitivity).

Some individuals may experience serious side effects while using Mellaril. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Irregular heartbeat, fainting, cardiac arrhythmias, or symptoms of torsade de pointes.
  • Neuroleptic malignant syndrome (NMS), including fever, severe muscle rigidity, mental status changes, and unstable blood pressure.
  • Parkinsonism, tardive dyskinesia, or uncontrolled movements of the face, tongue, or body.
  • Seizures.
  • Severe allergic reactions, including hives, swelling, or trouble breathing.
  • Severe dizziness or fainting.
  • Vision changes, including reduced acuity of vision, brownish coloring of vision, and impairment of night vision.

These are not all of the possible side effects of Mellaril. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Mellaril, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

  • History of breast cancer.
  • Epilepsy.
  • Heart disease.
  • History of blood cell problems, including agranulocytosis or leukopenia.
  • History of falls or risk of falls.
  • Parkinson's disease.

  • Taking other medications that prolong the QT interval.
  • Congenital long QT syndrome.
  • History of cardiac arrhythmias.
  • Concurrent use of drugs that reduce the metabolism of thioridazine, including fluoxetine, paroxetine, and fluvoxamine.
  • Severe central nervous system (CNS) depression or comatose state.
  • Extreme heart disease.

Some symptoms, such as agitation may improve within days of starting treatment. However, full improvement in schizophrenia symptoms may take several weeks of continuous treatment.

When Mellaril is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

Antidepressants (fluoxetine, paroxetine, fluvoxamine, bupropion), antipsychotics (pimozide, ziprasidone, lithium, chlorpromazine), heart medications (dofetilide, amiodarone, propranolol, pindolol - may increase side effects, including the risk of a prolonged QT and Torsades de Pointes.

Antidepressants, antihistamines, and atropine-like medications - may increase anticholinergic side effects.

Codeine and other central nervous system depressants - may increase sedation.

Mellaril tablets are available in the following strengths: 10 mg, 25 mg, 50 mg, and 100 mg.

It should be stored at room temperature, out of the reach of children and pets.

Mellaril was originally manufactured by Novartis Pharmaceuticals Corporation.

Yes, it is available from many manufacturers of generic drugs.

Do not stop taking Mellaril suddenly unless instructed by your healthcare provider. Abrupt discontinuation may increase the risk of withdrawal symptoms or worsening psychiatric symptoms. Your doctor may gradually reduce your dose if treatment needs to be discontinued.

Thioridazine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Thioridazine is excreted into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue breastfeeding or discontinue the medication.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.

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Important information about buying Mellaril from UniversalDrugstore™

We ship to destinations within the United States, including Alaska and Hawaii, as well as internationally. Delivery typically takes about 2 weeks for orders shipped within the U.S. and Canada, and about 4 weeks for international orders, depending on your location and customs processing.

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
  • Price match guarantee – we’ll match competitor pricing on qualifying medications
  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.