Buy Invega Sustenna Online (Paliperidone Palmitate)
What is Invega Sustenna?
What is Invega Sustenna?
Invega Sustenna is indicated for the treatment of schizophrenia in adults and teenagers who are 12 years old and older. It is also indicated for the treatment of adults with schizoaffective disorder as monotherapy or along with mood stabilizers and/or antidepressants.
Order Invega Sustenna online today and save!
Purchase Invega Sustenna from Universal Drugstore today and save!
Select your dosage:
- All Strength's
- 78mg/0.5mL
- 117mg/0.75mL
- 156mg/mL
- 234mg/1.5mL (156mg/1mL)
Invega Sustenna brand
Invega Sustenna 78mg/0.5mL
Prescription RequiredProduct of United Kingdom
Marketed as Xeplion Pre-Filled Syringe 50mg/0.5mL in United Kingdom.
Product of Canada
Marketed as Invega Sustenna 50mg/0.5mL in Canada
Invega Sustenna 117mg/0.75mL
Prescription RequiredProduct of United Kingdom
Marketed as Xeplion Pre-Filled Syringe 75mg/0.75mL in United Kingdom.
Product of Canada
Marketed as Invega Sustenna 75mg/0.75mL in Canada
Invega Sustenna 156mg/mL
Prescription RequiredProduct of United Kingdom
Marketed as Xeplion Pre-Filled Syringe 100mg/mL in United Kingdom.
Product of Canada
Marketed as Invega Sustenna 100mg/mL in Canada
Invega Sustenna 234mg/1.5mL (156mg/1mL)
Prescription RequiredProduct of United Kingdom
Marketed as Xeplion Pre-Filled Syringe 150mg/1.5mL in United Kingdom.
Product of Canada
Marketed as Invega Sustenna 150mg/1.5mL in Canada
Paliperidone Palmitate (generic Invega Sustenna)
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Important information about Invega Sustenna
The active ingredient in Invega Sustenna is paliperidone palmitate. It belongs to a class of medications known as atypical antipsychotics or second-generation antipsychotics (SGAs). It works to rebalance dopamine and serotonin to improve thinking, mood, and behavior.
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Invega Sustenna. However, the following is a synopsis of the general guidelines for the use of Invega Sustenna:
- Take this medication exactly as directed by your physician.
- Invega Sustenna is a long-acting injection that is given into the muscle (IM) by your healthcare provider. They will determine your dose based on how you respond to the medication.
- Avoid the use of alcohol while being treated with Invega Sustenna.
The most common side effects of Invega Sustenna seen in clinical trials include:
- Fast heart rate (tachycardia).
- Restlessness (akathisia).
- Sleepiness or drowsiness.
- Parkinsonism.
- Weight gain.
- Upset stomach.
- Anxiety.
- Constipation.
- Injection site reactions.
- Extrapyramidal symptoms.
- Muscle stiffness.
- Stuffy nose.
- Dry mouth.
Some individuals may experience serious side effects while using Invega Sustenna. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Severe allergic reaction - hives, itching, swelling, rash.
- Tardive dyskinesia - uncontrolled muscle movements.
- Neuroleptic malignant syndrome (NMS) - high fever, muscle stiffness, confusion, sweating, changes in heart rate and blood pressure.
- QT prolongation.
- Metabolic changes - hyperglycemia (high blood sugar), dyslipidemia, weight gain.
- Hyperprolactinemia (increased prolactin levels).
- Orthostatic hypotension and syncope.
- Leukopenia.
- Priapism.
- Seizures.
- Body temperature regulation.
- Cerebrovascular adverse reactions.
- Low white blood cell count - fever, chills, sore throat, cough, trouble breathing.
These are not all of the possible side effects of Invega Sustenna. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
Before starting Invega Sustenna, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:
- Heart rhythm problems (arrhythmia, long QT syndrome).
- Cholesterol or triglyceride problems.
- Lewy body dementia.
- Neuroleptic malignant syndrome (NMS).
- High or low blood pressure.
- Low white blood cell (WBC) count.
- Uncontrolled muscle movements in your face.
- Stomach or intestinal disorder.
- Liver or kidney disease.
- Seizures.
- Electrolyte imbalance.
- Diabetes.
- Breast cancer.
Boxed Warning
- Increased risk of death in elderly patients with dementia related psychosis.
- Previous hypersensitivity/allergic reaction to paliperidone or risperidone (Risperdal).
It will probably take several weeks to see big enough changes in your symptoms to decide if paliperidone is the right medication for you.
When Invega Sustenna is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Alcohol consumption.
- Use of illegal drugs.
- Carbamazepine.
- Parkinson’s disease medications (levodopa).
- Rifampin.
- St. John’s Wort.
- Medications that cause QT prolongation.
- Medication for high blood pressure.
- Anticholinergic medications.
- Medications that cause dizziness and sleepiness (prescription pain medicines, sleep medicines, medicines for anxiety).
Invega comes in a variety of dosage forms and formulations, including:
- Invega - extended-release oral tablet: 1.5 mg, 3 mg, 6 mg, 9 mg.
- Invega Sustenna - extended-release intramuscular suspension: 39 mg, 78 mg, 117 mg, 156 mg, 234 mg.
- Invega Trinza - extended-release intramuscular suspension: 273mg, 410mg, 546mg, 819mg.
- Invega Hafyera - extended-release intramuscular suspension: 1,092 mg, 1,560 mg.
Store this medication at room temperature and keep it out of reach of children.
Janssen Pharmaceuticals is the pharmaceutical company that manufactures Invega Sustenna.
There are no lower-cost generics available for the brand-name Invega Sustenna.
Do not stop or adjust your use of this medication without first consulting with your healthcare provider. Stopping this medication suddenly may cause new or worsening symptoms of schizophrenia or schizoaffective disorder.
Antipsychotic use during the third trimester of pregnancy has a risk for abnormal muscle movements (extrapyramidal symptoms) and/or withdrawal symptoms in newborns. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
This medication is known to pass into breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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Click to joinImportant information about buying Invega Sustenna from UniversalDrugstore™
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
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Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
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Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Yes! We offer:
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Medical Disclaimer
The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Jamie Winn, PharmD, is a licensed pharmacist and seasoned medical content reviewer with over 20 years of experience in clinical pharmacy, patient care, and healthcare leadership.
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Shirley is a Medical Writer and first-year Doctor of Pharmacy (PharmD) student at the University of Alberta, where she is building on her strong foundation in health sciences and patient care.
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