Rexulti
Rexulti (brexpiprazole) is an atypical antipsychotic used in the treatment of various psychiatric and mental health conditions. Most commonly, it is used in the treatment of schizophrenia in those 13 years of age and older. It may also be used in the treatment of agitation associated with dementia due to Alzheimer’s disease. Additionally, it can be used as an adjunctive treatment to antidepressants in adults with major depressive disorder (MDD).
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Rexulti Prescription Required
Rexulti Prescription Required
Rexulti Prescription Required
Rexulti Prescription Required
Rexulti Prescription Required
Rexulti Prescription Required
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Important information about Rexulti
How does Rexulti work?
The active ingredient in Rexulti is brexpiprazole. This medication falls within the same class as aripiprazole. The exact mechanism of action of brexpiprazole is unknown. However, it is thought that the effects of Rexulti may be due to activity at serotonin and dopamine receptors, making it effective in schizophrenia and as an adjunctive therapy for the treatment of major depressive disorder.
How do you use Rexulti?
Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Rexulti. However, the following is a synopsis of the general guidelines for the use of Rexulti:
- Typically, Rexulti is taken by mouth once a day with or without food.
- Use exactly as prescribed. Do not exceed the recommended dose or duration of use.
- Your starting dose of Rexulti may not be the one you continue for the rest of the treatment. Your healthcare provider may make dosage adjustments based on your clinical response and tolerability.
- Rexulti can cause drowsiness. Do not drive or operate heavy machinery until you are familiar with how Rexulti affects you.
- Rexulti can affect your body’s ability to regulate body temperature. Avoid becoming dehydrated or increasing your body temperature too much by staying cool during hot weather and maintaining adequate fluid intake.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
What are the side effects of Rexulti?
The most common side effects of Rexulti seen in clinical trials include:
- Weight gain
- Sleepiness
- Dizziness
- Symptoms of common cold like runny nose, cough, sore throat, fatigue, or fever
- Feelings of inner restlessness (akathisia)
- Headache
- Tremor
- Larger appetite
- Anxiety
- Heartburn
- Diarrhea
Some individuals may experience serious side effects while using Rexulti. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:
- Signs of suicidal thoughts or behaviors. Caregivers and the user should watch for thoughts about suicide or dying, new or worsening anxiety, panic attacks, new or worsening depression, trouble sleeping, mania, aggression, or any other unusual changes in mood, thoughts, and behaviors.
- Signs of stroke, especially in elderly people with dementia-related psychosis, such as slurred speech, facial drooping, or weakness in one arm.
- Signs of neuroleptic malignant syndrome (NMS) such as changes in pulse, blood pressure, heart rate, or breathing, increased sweating, fever, stiffness, or confusion. This is a life-threatening condition that must be addressed right away.
- Uncontrolled movements (tardive dyskinesia) especially in the face, tongue, or limbs.
- Signs of high blood sugar (hyperglycemia) such as excess thirst and hunger, nausea, increased urination, excessive fatigue, confusion, or fruity smell to the breath.
- Unusual and uncontrollable urges that may manifest as addictions or compulsions (gambling, shopping, binge eating, sexual urges).
- Signs of orthostatic hypotension such as dizziness when going from sitting to standing.
- Seizures.
- Feeling too warm. This could be a sign that you are having issues controlling your body temperature.
- Difficulty swallowing.
- Low white blood cell count that may be indicative of leukopenia or agranulocytosis. It is often symptomless so your healthcare provider may obtain baseline tests and send you for blood work during the course of treatment to ensure your count is within range.
- Excess sleepiness and drowsiness resulting in falls or impairment of daily activities.
These are not all of the possible side effects of Rexulti. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.
What are the warnings or precautions for Rexulti?
Before starting Rexulti, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:
- Heart problems
- History of stroke
- Low or high blood pressure
- Personal or family history of diabetes
- High cholesterol or triglycerides
- Seizures
- Kidney problems
- Liver problems
- Low white blood cell count
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed
Boxed Warning
- The use of antipsychotic drugs in elderly patients with dementia-related psychosis can result in an increased risk of death. Rexulti is not approved for treating psychosis from dementia due to Alzheimer’s disease if there is no agitation.
- When used as an antidepressant, Rexulti can increase the risk of suicidal thoughts and behaviors in children and young adults.
Are there any contraindications with Rexulti?
Do not use Rexulti if you have:
- An allergy to brexpiprazole or any of the other ingredients found in Rexulti
How long does it take Rexulti to work?
Rexulti does take some time to work. Some benefits may be seen after a couple of weeks of regular use but is likely that you will need to take this medication daily for 6 to 8 before you see a noticeable difference.
What interacts with Rexulti?
When Rexulti is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:
- Strong CYP3A4 inhibitors or inducers
- Strong CYP2D6 inhibitors (Note: dosage adjustments may not be required with fluoxetine and paroxetine but still notify your healthcare provider if you are using these medications)
What doses of Rexulti are available?
Rexulti tablets are available in the following strengths:
- 0.25 mg
- 0.5 mg
- 1 mg
- 2 mg
- 3 mg
- 4 mg
How do I store Rexulti?
Rexulti should be stored at room temperature away from light and out of reach of children.
Which pharmaceutical company manufactures Rexulti?
Rexulti is manufactured by the pharmaceutical company Otsuka Pharmaceuticals.
Is there a generic version of Rexulti?
No, there is not a generic version of Rexulti available.
How do I stop taking Rexulti?
Rexulti will need to be gradually tapered in order to prevent the negative effects of sudden discontinuation. Consult your doctor or pharmacist before starting, stopping, or changing medications while taking Rexulti.
Can Rexulti be used if I am pregnant?
The use of antipsychotic medications in pregnancy can carry some risks. In regards to Rexulti, it can cause harm to the unborn child, especially if used in the third trimester. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.
Can Rexulti be used if I am breast feeding?
It is unknown if Rexulti passes into the breastmilk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.
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What happens after I place my order for Rexulti with Universal Drugstore?
Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.
How long does it take to process and deliver my order for Rexulti?
Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.
Can I track my order of Rexulti?
Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.
What should I do if there is an issue with my order for Rexulti?
Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.
How is my medication packaged to ensure privacy and safety?
All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.
Does Universal Drugstore ship medications that require refrigeration or special handling?
Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.
What are the shipping costs, and does Universal Drugstore offer free delivery?
Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.
Does Universal Drugstore accept Medicare or Medicaid for prescriptions?
Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.
Can I use private health insurance to cover my prescription from Universal Drugstore?
Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Unievrsal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.
How secure is my payment information when ordering from Universal Drugstore?
We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.
Can I order a generic alternative to Rexulti?
Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.
Do I need a prescription to order Rexulti?
If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription.
Can I order multiple medications at once?
Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.
Can I refill my prescription through Universal Drugstore?
Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.
Does Universal Drugstore offer discounts or price matching?
Yes! We offer:
- Up to 80% savings on medications
- Price match guarantee – we’ll match competitor pricing on qualifying medications
- 10% off your first order for new customers
How can I contact Universal Drugstore for additional support?
We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.
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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment.
Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.