Stelazine

(Trifluoperazine Hydrochloride)

The active ingredient in Stelazine is trifluoperazine hydrochloride. It is an antipsychotic that falls under the drug class known as phenothiazines. It works by inhibiting the dopamine receptors, allowing for more of this neurotransmitter to stay in the brain. This helps prevent symptoms of schizophrenia, like hallucinations and delusions.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Stelazine. However, the following is a synopsis of the general guidelines for the use of Stelazine:

• This medication is typically taken twice daily.
• Ensure that no alcohol is taken with this medication, as it can make you severely drowsy and slow down your breathing, which can be dangerous.
• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose.
• Do not stop taking Stelazine without talking to your provider first. They may have you stop the medication gradually to prevent any withdrawal symptoms.

Some mild and common side effects of Stelazine include:

• Dry mouth
• Photosensitivity, which can lead to sunburns
• Dizziness
• Blurred vision
• Constipation
• Weight gain
• Drowsiness
• Lactation
• Inconsistency in menstrual period cycles

Some individuals may experience serious side effects while using Stelazine. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reaction: skin reaction including hives, trouble breathing, swelling of face or lips
• Neuroleptic Malignant Syndrome (NMS): muscle stiffness, changes in heart rate
• Orthostatic hypotension
• Extrapyramidal symptoms or tardive dyskinesia: uncontrolled movements, twisting motions, lip smacking
• Liver damage: dark urine, jaundice, and loss of appetite
• High prolactin production
• Low white blood cell count
• Parkinsonism symptoms: drooling and balance problems

These are not all of the possible side effects of Stelazine. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Stelazine, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Glaucoma
• Liver porblem
• Hypersensitivity to the medication
• Blood disorders
• Dementia-related psychosis
• Breast Cancer
• Seizure
• Low blood pressure
• Heart problems or chest pain
• History of Neuroleptic Malignant Syndrome
• Exposure to insecticides
• History of drinking alcohol

Boxed Warning

• Caution that patients diagnosed with dementia-related psychosis are at an increased risk of death when they are treated with antipsychotic drugs.

• Known allergy to Stelazine or to any of its inactive ingredients
• Comatose or severe depression due to existing blood disorders, severe liver damage, CNS depressants, and bone marrow suppression

The effects of this medication will take about 2 to 3 weeks to begin working.

When Stelazine is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Lithium
• Blood thinners, including warfarin
• Propranolol
• Phenytoin
• Levodopa
• Benzodiazepines
• Anticholinergic medications that contain antihistamines, which are used for Parkinson's disease or an overactive bladder

The dosage forms available include oral tablets. The strengths available include 1 mg, 2 mg, 5 mg, and 10 mg.

This medication should be stored at room temperature and away from the reach of children.

The pharmaceutical company that manufactures Stelazine is Advanz Pharma.

There are lower-cost alternatives to the brand-name Stelazine.

Before stopping this medication, consult your healthcare provider.

It is unknown if Stelazine is safe in pregnancy. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Stelazine can be found in your breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.