Buy Brexafemme Online

(Ibrexafungerp Citrate)

The active ingredient in Brexafemme is ibrexafungerp citrate.

• Ibrexafungerp is a triterpenoid antifungal drug.
• It works by inhibiting the fungal cell wall, which weakens and kills Candida species.
• Unlike azoles, it has a unique mechanism of action and shows in vitro activity against many Candida species, including those resistant to azoles.
• The oral ibrexafungerp formulation allows systemic treatment of VVC and may reduce recurrence in RVVC.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Brexafemme. However, the following is a synopsis of the general guidelines for the use of Brexafemme:

• Take Brexafemme by mouth with or without food as prescribed.
• Swallow the 150 mg film-coated tablets whole; do not crush or chew.
• The typical regimen involves a single dose or multiple tablets over a short period, depending on your doctor’s instructions.
• Complete the full course even if symptoms improve before finishing the tablets.
• If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and return to your regular schedule.
• Avoid taking Brexafemme with drugs or herbal products that may interact, such as St. John’s Wort or rifampin, which can affect CYP3A4 metabolism.
• Confirm pregnancy status with a pregnancy test before treatment if applicable and discuss birth control measures if needed.

Some mild or most common side effects of Brexafemme seen in clinical trials as compared to placebo include:

• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Hot flashes

Some individuals may experience serious side effects while using Brexafemme. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic adverse reaction, including rash, hives, or difficulty breathing
• Signs of liver problems, such as yellowing of the skin or eyes

These are not all of the possible side effects of Brexafemme. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the U.S. Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Brexafemme, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Liver disease or abnormal liver function tests
• Pregnancy or plans to become pregnant
• Use of other medications that are CYP3A4 inhibitors or inducers
• History of recurrent vulvovaginal candidiasis (RVVC)
• Allergic reactions to antifungal drugs or inactive ingredients

Boxed Warning

• Brexafemme can cause a risk of embryofetal toxicity and is therefore contraindicated in pregnancy.

• Known hypersensitivity to ibrexafungerp or any of its inactive ingredients
• Severe liver impairment unless directed by a healthcare provider

Many patients notice symptom improvement within a few days, but complete resolution of vaginal yeast infection usually occurs within 7 days.

When Brexafemme is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Rifampin
• St. John’s Wort
• Other antifungal medications like fluconazole or itraconazole
• Certain oral contraceptives (discuss alternatives if needed)

Brexafemme is available in the following strengths and dosage forms:

• 150 mg film-coated tablets

Store at room temperature away from light and moisture, and keep in the original container. Keep out of reach of children.

Brexafemme is manufactured by Scynexis, headquartered in Jersey City.

Currently, there is no generic version of Brexafemme.

Take Brexafemme exactly as prescribed and do not stop early unless directed by your healthcare provider. Completing the full course ensures the infection is fully treated and reduces the risk of recurrence.

A pregnancy test may be advised before starting treatment. Women who can become pregnant should use effective birth control throughout treatment with Brexafemme and for 4 days after the last dose.

It is not known if Brexafemme is found in breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.