Brolene Eye Drops

The active ingredient in Brolene is propamidine isetionate, an antibacterial that reduces the growth of bacteria.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Brolene. However, the following is a synopsis of the general guidelines for the use of Brolene:

1. Any other eye drops or ointments should be applied at least ten minutes before this one.

2. It is recommended to rinse the affected eye(s) before use with saline solution or warm water that has previously been boiled.

3. Wash your hands before and after each use. Shake the bottle well.

4. Do not allow the dropper tip to touch your eye, fingers, or any other surface to avoid contamination.

5. To apply the drops, tilt your head up and pull down on your lower eyelid of the affected eye while looking up. Then squeeze the bottle to release one drop of the solution into your eye.

6. Following administration, close your eyes gently and hold pressure on your tear duct (inner corner of your eye, by your nose) for one minute. Then repeat for the other eye if needed. You can use a clean tissue to wipe any residue on your face.

7. If you wear contact lenses, remove them before administering, then you can re-insert them 15 minutes after.

8. If you use more than one eye drop, wait at least 5 minutes between administrations.

9. You should discard the bottle 4 weeks after first opening it, and do not use it past the expiry date.

Some mild and common possible side effects of Propamidine seen in clinical trials include:

• Burning sensation in the eyes.
• Eye pain.
• Dry eyes.

Some individuals may experience serious side effects while using Brolene. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Worsening symptoms of conjunctivitis (red/ puffy eyes) or severe pain/ burning upon instillation.
• Serious life-threatening allergic reactions, which may present as skin rash, hives, swelling of the face, mouth, or tongue, and/ or trouble breathing (anaphylaxis).

These are not all of the possible adverse reactions of Brolene. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Brolene, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions.

There are no warnings or precautions for Brolene.

Hypersensitivity or allergy to propamidine isethionate, the preservative benzalkonium chloride, or the inactive ingredients ammonium chloride, sodium chloride, or sodium hydroxide.

You should notice a benefit with Brolene within 2 days, and complete resolution within 7 days. If you do not, stop using it and let your doctor know.

When Brolene is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions.

There are no known drug interactions with Brolene.

Brand-name Brolene is supplied as eye drops containing 1mg/mL propamidine isetionate, or eye ointment containing 1.5mg/mL.

It should be stored in a cool, dry place, away from the reach of children or pets.

It is manufactured by Sanofi-Aventis.

No, there is no generic version of these eye drops.

Barring any serious side effects as listed above, or as directed by a physician, you should not use this medication for longer than 7 days.

The safety of Brolene in pregnancy is not known.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

The safety of Brolene in breastfeeding is not known.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.