Lotrisone Cream

The active ingredients in Lotrisone Cream are betamethasone dipropionate and clotrimazole. Clotrimazole is an azole antifungal that stops the growth of fungus by preventing the production of ergosterol, a substance the fungus needs to build its cell walls. Without ergosterol, the fungal cells weaken and die. This antifungal mechanism of action helps treat infections like ringworm, jock itch, and athlete’s foot.

Betamethasone dipropionate is a high-potency topical corticosteroid that reduces inflammation in the affected skin area. It helps relieve symptoms such as redness, itching, and swelling. By calming the immune response in the skin, betamethasone helps improve comfort while clotrimazole clears the infection.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Lotrisone Cream. However, the following is a synopsis of the general guidelines for the use of Lotrisone Cream:

• Apply a thin layer of the cream to the affected skin and surrounding area, usually twice daily (morning and evening).
• Wash your hands before and after applying the cream.
• Use only enough cream to cover the affected area lightly. Do not bandage or cover the area unless instructed by your healthcare provider.
• Avoid contact with eyes, mouth, or other mucous membranes.
• Do not apply Lotrisone Cream on the face, underarms, groin area (unless directed for jock itch), or on broken or irritated skin.
• Treatment typically lasts for 1 to 2 weeks for jock itch or ringworm, and up to 4 weeks for athlete’s foot. Do not use longer than prescribed.
• If you miss a dose, apply it as soon as you remember. If it’s almost time for the next dose, skip the missed one; do not double up.
• Improvement is often seen within the first week, but continue using the cream for the full prescribed duration to prevent recurrence of infection.

Some mild or common side effects of Lotrisone Cream include:

• Burning, stinging, or itching at the application site.
• Dryness or skin irritation.
• Stretch marks or thinning skin (with prolonged use).
• Changes in skin color in treated areas.

Some individuals may experience serious side effects while using Lotrisone Cream. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Signs of an allergic reaction (hives, severe skin rash, swelling, difficulty breathing).
• Blurred vision, eye pain, or signs of glaucoma or cataracts may occur if the cream contacts the eyes.
• Unusual tiredness, weight loss, or high blood sugar (hyperglycemia).
• Skin infection that worsens or does not improve.
• Symptoms of Cushing’s syndrome (such as moon face, increased fat around the neck, or thinning arms and legs).

These are not all of the possible side effects of Lotrisone Cream. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Lotrisone Cream, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Skin infections that are bacterial or viral (such as herpes or chickenpox).
• Diabetes or high blood sugar.
• Eye conditions like glaucoma or cataracts.
• Problems with your adrenal gland.
• A weakened immune system.
• History of allergic reactions to corticosteroids or antifungal medications.
• Lotrisone Cream should not be used for diaper dermatitis (diaper rash) or on the face. Use caution when applying to thin areas of skin, such as the groin or underarms. Prolonged use on large areas or under occlusive dressings may increase the risk of systemic absorption, which can lead to side effects like adrenal suppression or high blood sugar.
• Children and adolescents may be more sensitive to topical corticosteroids and may experience slowed growth or other systemic effects.

Lotrisone Cream should not be used in individuals who:

• Have a known hypersensitivity to clotrimazole, betamethasone dipropionate, or any ingredients in the cream.
• Have viral, bacterial, or parasitic skin infections not caused by fungi.

Lotrisone Cream typically begins to relieve symptoms like itching and redness within a few days of starting treatment. However, full resolution of the fungal infection may take 1 to 4 weeks of treatment, depending on the area and severity. Continue using the medication for the full prescribed duration, even if symptoms improve early, to prevent the growth of fungus from returning.

When Lotrisone Cream is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Other topical steroids or antifungal creams.
• Systemic corticosteroids (like prednisone or dexamethasone).
• Immunosuppressants.
• Diabetes medications, as corticosteroids, may raise blood sugar levels.
• Any products applied to the same areas of skin.

Lotrisone is available as a topical cream and lotion containing clotrimazole 1% and betamethasone dipropionate 0.05%. Both forms are for external use only.

Your healthcare provider will determine the best dosage form and duration of treatment for your specific fungal skin infection.

Store Lotrisone Cream at room temperature, between 20°C and 25°C (68°F to 77°F). Protect it from heat, moisture, and direct sunlight. Do not freeze. Keep the tube tightly closed and out of reach of children and pets.

Do not use the cream after the expiration date printed on the packaging. Dispose of any unused medication safely according to local regulations.

Lotrisone Cream is manufactured by Merck & Co., Inc.

Yes. There are generic versions of brand-name Lotrisone Cream available.

Do not stop using Lotrisone Cream suddenly without medical advice. If your infection clears before completing the prescribed duration, continue for the full course to prevent recurrence. If you need to stop treatment or switch medications, your healthcare provider will guide you on how to discontinue use safely.

If you are pregnant or planning to become pregnant, talk to your doctor before using Lotrisone Cream. There is limited information about its safety during pregnancy, and it should be used only if clearly needed and prescribed by your healthcare provider. Avoid applying to large areas or for prolonged periods during pregnancy.

If you are breastfeeding or plan to breastfeed, speak with your doctor before using Lotrisone Cream. It is unknown whether betamethasone or clotrimazole passes into breast milk when used topically, but corticosteroids may be absorbed through the skin. Avoid applying the cream to areas of skin that may come into direct contact with the infant or near the breast area.