Inderal

The active ingredient in Inderal is propranolol hydrochloride which is a beta-adrenergic blocker. It decreases blood pressure and helps with chest pain by relaxing your blood vessels to improve blood flow and slowing your heart rate.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Inderal. However, the following is a synopsis of the general guidelines for the use of Inderal:

• Inderal is typically taken 1 to 4 times daily, depending on which formulation you use. It can be taken with or without food.
• Children's weight determines their dosage. If your child's weight changes, their usual dose may also change.
• Regular checks of your blood pressure and heart function are necessary.
• If you have a planned surgery, let your doctor know.
• If you abruptly stop taking Inderal, your condition might worsen. Before stopping the medication, consult your doctor.
• Certain medical test results may be impacted by propranolol. Inform any medical professional you see that you take Inderal.
• Even if you feel well, continue taking this medication if you have high blood pressure. Symptoms of high blood pressure are frequently absent.
• If you miss a dose of Inderal, take it as soon as you can. But if your next dose is almost due, skip the missed dose and take it at its next scheduled time. Avoid taking two doses at once.

The most common side effects of Inderal include:

• Tiredness.
• Weakness.
• Dizziness.
• Nausea or vomiting.
• Diarrhea.
• Constipation.
• Dry eyes.
• Trouble sleeping.

Some individuals may experience serious side effects while using Inderal. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Increased risk of heart failure: shortness of breath, rapid weight gain, extreme fatigue, chest pain, slow heartbeat, and swelling in the legs, ankles, or feet.
• Bronchospasm: chest constriction, difficulty breathing, wheezing, coughing, lightheadedness.
• Allergic reactions: hives, trouble breathing, and facial, throat, or lip swelling.
• Serious skin reactions: fever, blistering or peeling skin, rash, and skin pain.

These are not all of the possible side effects of Inderal. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Inderal, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• If you are allergic to propranolol, have asthma, have a history of fainting due to slow heartbeats or irregular heartbeats, severe heart failure, or have a serious heart condition like "sick sinus syndrome" or heart block, or heart disease you should not use Inderal.
• Tell your doctor if you have ever experienced congestive heart failure or slow heartbeats to ensure that Inderal is safe for you.
• Emphysema, bronchitis, or other respiratory conditions.
• Diabetes: Propranolol may make it more difficult to detect low blood sugar (hypoglycemia).
• Kidney or liver disease.
• A thyroid condition like hyperthyroidism.
• Pheochromocytoma (adrenal gland tumor).
• Circulation issues (like Raynaud's syndrome).
• If you smoke.

Certain medical conditions or circumstances are known as contraindications, and they raise safety concerns about a medication's use. It is not safe for you to take propranolol, so let your doctor know if you have any of the following conditions or if any of the following apply to you.

• Heart-related shock (cardiogenic shock).
• Bradycardia (slow heartbeat).
• Asthma.

Inderal works one to four hours after taking a dose but may take up to a week to reach its full effect.

When Inderal is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Colestipol.
• Coumadin/Jantoven (warfarin).
• Certain antidepressants.
• Some blood pressure medications like calcium channel blockers.
• Certain antibiotics.
• Medication for a prostate condition.
• Steroids.
• Cimetidine.
• NSAIDs (nonsteroidal anti-inflammatory drugs) such as celecoxib, diclofenac, indomethacin, meloxicam, naproxen (Aleve), ibuprofen (Advil, Motrin), and aspirin, among others.

Propranolol tablets and oral solution:

High blood pressure: 40 mg taken orally twice a day is the usual starting dosage. Two times a day, 120–240 mg is the usual maintenance dose.

The usual dosage for atrial fibrillation (A.Fib) is 10–30 mg taken orally three or four times a day, before meals and before bed.

Heart protection following a heart attack: 40 mg taken orally three times a day is the usual starting dosage. Three times a day, 60–80 mg is the usual maintenance dosage.

Preventing migraines: The usual maintenance dosage is 160–240 mg taken orally in divided doses per day.

The usual dosage for chronic chest pain is 80–320 mg taken orally each day, divided into smaller doses, and taken two to four times a day.

Tremors: 40 mg taken orally twice a day is the usual starting dosage. A daily total of 120 mg administered in divided doses is the usual maintenance dose.

For hypertrophic subaortic stenosis, the usual oral dosage is between 20 and 40 mg. Before meals and before going to bed, three or four times a day.

Adrenal gland tumor (pheochromocytoma): 60 mg taken orally every day in divided doses for three days before surgery is the usual dosage. The usual dosage, if surgery is not an option, is 30 mg taken orally every day in divided doses.

Inderal LA extended-release capsules

Additionally, propranolol extended-release is available as Inderal XL and Innopran XL, which are authorized solely for the treatment of high blood pressure.

High blood pressure: 80 mg taken orally once a day is the usual starting dosage. One daily dose of 120–160 mg is the usual maintenance dosage.

Preventing migraines: 80 mg taken orally once a day is the usual initial dosage. 160 mg to 240 mg once daily is the usual maintenance dosage.

Chronic chest pain: 80 mg taken orally once a day is the usual initial dosage. 160 mg once daily is the usual maintenance dosage.

The typical dosage for hypertrophic subaortic stenosis is 80–160 mg taken orally once a day.

Store Inderal at room temperature and out of reach of children.

ANI Pharmaceuticals Inc. is the company that manufactures Inderal.

There are several lower-cost generic versions available of Inderal.

Your doctor will assist you in creating a taper schedule to gradually wean off of Inderal, as they do with many medications. Your body will have time to adapt as you gradually reduce your dosage, which is typically done over two to four weeks. Stopping Inderal abruptly could worsen your condition or increase your risk of heart attack or other heart problems.

Propranolol use has not been associated with the risk of major birth defects or miscarriage. However, you should talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Propranolol is found in breast milk in small amounts but it is not known what effects it has on your breastfed infant or milk production. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.