Inderal LA

(Propranolol Hydrochloride ER)

The active ingredient in Inderal LA is propranolol hydrochloride. This medication belongs to a class of medications known as adrenergic beta blockers. Blocking these receptors helps your heart beat more slowly. These effects can help your heart work better, lower blood pressure, and may reduce your risk for serious cardiovascular events like heart attack and stroke.

Inderal LA can also be used to prevent migraine headaches. It works by relaxing the blood vessels in the brain that cause migraines.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Inderal LA. However, the following is a synopsis of the general guidelines for the use of Inderal LA:

• Use this medication exactly as directed by your healthcare provider. They may occasionally change your dose to make sure you get the best results.
• Inderal LA is typically taken by mouth once daily. You may take it with or without food, but take it the same way each time, around the same time each day.
• If you miss a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and only take the next dose.

The most common side effects of Inderal LA include:

• Tiredness.
• Slow heartbeat (bradycardia).
• Dizziness.
• Lightheadedness.
• Diarrhea.
• Constipation.

Some individuals may experience serious side effects while using Inderal LA. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe, life-threatening allergic reaction - hives, itching, skin rash, swelling, and trouble breathing.
• Raynaud's - cool, numb, or painful fingers or toes.
• Heart rate changes - feeling lightheaded, abnormal heart rhythms, chest pain, and shortness of breath.
• Low blood pressure (hypotension) - feeling lightheaded.
• New or worsening heart failure - trouble breathing and rapid weight gain.
• Breathing problems - trouble breathing due to bronchospasm.

These are not all of the possible side effects of Inderal LA. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Inderal LA, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Heart failure.
• Hyperthyroidism (overactive thyroid).
• Hypoglycemia (low blood sugar).
• Irregular heartbeat.
• Pheochromocytoma (tumor of the adrenal gland).
• Diabetes.
• Liver problems.
• Kidney problems.
• Asthma or other lung problems (bronchitis, emphysema).

• Previous hypersensitivity/allergic reaction to Inderal LA ingredients.
• Cardiogenic shock.
• Sinus bradycardia and greater than first-degree heart block.
• Bronchial asthma.

Depending on the condition being treated, it usually starts to work in a few hours but may take up to a week to reach its full effect.

When Inderal LA is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Digoxin.
• Nonsteroidal anti-inflammatory drug (NSAID) (ibuprofen, naproxen).
• Clonidine.
• Warfarin.
• Alpha-blockers for high blood pressure (terazosin, doxazosin).
• Cimetidine.
• Levothyroxine.
• Steroid medication (prednisone).
• Theophylline.
• Diabetes medication.
• Medications for depression or schizophrenia.
• Antidepressant medication (amitriptyline, imipramine).
• Heart or blood pressure medication (amiodarone, diltiazem, propafenone).
• Epinephrine.

Inderal LA is available in the following dosage forms and strengths, including:

• 60 mg oral extended-release capsules.
• 80 mg oral extended-release capsules.
• 120 mg oral extended-release capsules.
• 160 mg oral extended-release capsules.

Store this medication at room temperature and keep it out of the reach of children.

ANI Pharmaceuticals, Inc. is the pharmaceutical company that manufactures Inderal LA.

There are lower-cost generic options available for the brand-name Inderal LA.

Do not stop or adjust your use of this medication suddenly, as heart attacks and worsening of chest pain have occurred. Slowly reducing your dose over a period of time before stopping it completely is recommended.

It is not known if Inderal LA is safe for your unborn baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

This medication is known to pass into breast milk. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.