Sporanox

The active ingredient in Sporanox is itraconazole. It works by inhibiting the formation of ergosterol, which is an important component of the fungal cell wall. As a result, it stops the infection from growing and spreading.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide, before using Sporanox. However, the following is a synopsis of the general guidelines for the use of Sporanox:

• The liquid oral solution should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. It can be swished inside the mouth before the medication can be swallowed; the Sporanox capsule should be taken with food.

The most common side effects of Sporanox include:

• Edema or swelling
• Increased blood pressure
• Nausea
• Vomiting
• Headache
• Constipation
• Elevate liver enzymes
• Rash

Some individuals may experience serious side effects while using Sporanox. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Congestive heart failure (CHF): breathing problems, swelling, sudden weight gain, fatigue, dizziness, chest pain, lightheadedness, or rapid heart rate
• Abnormal heart rhythm (QT prolongation): dizziness, lightheadedness, chest pain, or heart palpitations
• Liver problems: loss of appetite, nausea, vomiting, fatigue, yellowing of the skin or whites of the eyes (jaundice), dark-colored urine, or pale-colored stools
• Hearing loss
• Serious, life-threatening allergic reaction: hives, swelling of your face, tongue, or throat, and shortness of breath

These are not all of the possible side effects of Sporanox. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Sporanox, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether you have:

• Congestive heart failure or other heart problems
• Cystic fibrosis
• Kidney dysfunction
• Liver problems
• Immunocompromised or weak immune system

Boxed Warning

• Patients diagnosed with Congestive heart failure should not be taking this medication.
• Sporanox should not be used if drug interactions occur including with the following medications: Methadone, Ticagrelor, Voclosporin and many more.

• If you develop allergic reactions to itraconazole or medications similar to it, such as ketoconazole or fluconazole.
• Solifenacin, fesoterodine, and colchicine should not be taken with Sporanox.
• Ensure antacids and proton pump inhibitors such as pantoprazole are spaced from itraconazole within 1 hour or 2 hours after dose administration.

Sporanox begins to work within a couple of days, but depending on the infection, response can also be seen in 1-2 weeks.

When Sporanox is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Cisapride
• Eletriptan
• Alfuzosin
• Irinotecan
• Cholesterol-lowering medications such as simvastatin, lovastatin, and lomitapide
• Avanafil
• Ranolazine
• Blood pressure-lowering medications such as eplerenone, nisoldipine, felodipine, and ivabradine
• Oral midazolam or triazolam
• Anti-psychotic medications, including lurasidone and pimozide
• Ergot alkaloids such as dihydroergotamine, ergotamine, and methylergonovine
• Heart rhythm medications, including quinidine, dronedarone, and disopyramide

-Venetoclax

• Dofetilide

Dosage forms for this medication include itraconazole capsules or an itraconazole oral solution.

This medication should be stored at room temperature.

The pharmaceutical company that manufactures Sporanox is Janssen.

There are lower-cost generics available for the brand-name Sporanox.

Ensure you speak with your pharmacist or doctor before stopping the medication, as stopping it too soon can allow for the recurrence of the infection.

Sporanox should not be used during pregnancy as it is unsafe for the baby. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Itraconazole can pass into breast milk and may affect the nursing baby, which can be unsafe. Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.