Dymista

Dymista contains azelastine hydrochloride and fluticasone propionate, which have 2 different mechanisms of action. Azelastine hydrochloride is an antihistamine that inhibits histamine, a substance that causes allergy symptoms, including a runny or itchy nose. Fluticasone propionate is a corticosteroid. It reduces swelling and inflammation in the nose, which helps to relieve congestion and reduce mucus production.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-approved product Labeling, Instructions for Use, and Medication Guide, before using Dymista. However, the following is a synopsis of the general guidelines for the use of Dymista:

• Shake the medicine bottle gently before each use.
• Avoid getting Dymista into your eyes or mouth.
• If the drug gets into your eyes, rinse with water for 10 minutes before calling your doctor.
• Children should use this medication only with the supervision of an adult.

The most common side effects of Dymista include:

• Drowsiness or sleepiness.
• Headaches.
• Nosebleeds.
• Blurred vision.

Some individuals may experience serious side effects while using Dymista. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Severe allergic reaction: hives, skin rash, swelling in the face, lips, tongue, or throat, trouble breathing.
• Increased risk of an infection. This can include fungal infections in the nose or throat area.
• Severe nasal passage problems, such as nasal ulcers and nasal septal perforation, which is a hole in the cartilage that separates the nose.
• Vision problems, including glaucoma or cataracts.
• Delayed growth in children.
• Altered levels of cortisol with long-term use.

These are not all of the possible side effects of Dymista. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Dymista, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including whether any of the following apply:

• Sores or ulcers inside the nose.
• An injury or surgery to your nose.
• Chickenpox or measles.
• TB, or any other infection or disease.
• Herpes infection of the eyes.
• Glaucoma or cataracts.
• Do not drink alcohol while using nasal azelastine/fluticasone. The risk of dizziness and sleepiness may be increased.

Patients with hypersensitivity to azelastine hydrochloride, fluticasone propionate, or any of its excipients. This includes microcrystalline cellulose, polysorbate 80, carmellose sodium, disodium edetate, phenethyl alcohol, benzalkonium chloride, and purified water.

Dymista, a dual-action nasal spray, begins working within 5-15 minutes, offering immediate relief from allergy symptoms such as a runny nose, sneezing, and an itchy or clogged nose.

When Dymista is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Ritonavir (Norvi, Kaletra).
• Antifungal medications include fluconazole, itraconazole, and ketoconazole.
• Cimetidine.

The recommended dose is one spray of Dymista Nasal Spray in each nostril twice daily. Each spray contains 137 mcg of azelastine and 50 mcg of fluticasone.

If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only use the next dose. Do not use double or extra doses.

Store at room temperature and keep out of reach of children.

Meda Pharmaceuticals, Inc. is the company that manufactures Dymista.

There are several lower-cost generic versions available of Dymista.

Do not stop using Dymista Nasal Spray without first consulting your doctor, as doing so can cause your symptoms to come back or worsen. If you have any more questions about the usage of this medication, consult your doctor.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Using azelastine with fluticasone nasal spray while breastfeeding may cause your breast milk to taste bitter. If you breastfeed while taking this medication, look for symptoms that your baby is not breastfeeding properly. Speak with your doctor about the best approach to feeding your baby.