Tigan

(Trimethobenzamide Hydrochloride)

The active ingredient in Tigan is trimethobenzamide hydrochloride, which is an antiemetic. Its mechanism of action involves inhibiting the desire to vomit by acting on the vomiting center of the brain.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Tigan. However, the following is a synopsis of the general guidelines for the use of Tigan:

• Tigan is often taken 3 to 4 times per day. Follow your doctor's dosing recommendations carefully.
• Tigan oral capsules are taken by mouth, and for the injectable, a healthcare provider will inject this medication intramuscularly.

The most common side effects of Tigan include:

• Headaches.
• Drowsiness.
• Disorientation or confusion.
• Blurred vision.
• Muscle cramps.
• Diarrhea.
• Rash.
• Tremors or Parkinson-like symptoms.

Some individuals may experience serious side effects while using Tigan. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Movement issues, including extrapyramidal symptoms like muscle spasms, tremors, restlessness, and difficulty swallowing or speaking.
• Changes in your brain function: seizures, depression, coma.
• Liver damage symptoms include yellowing of the skin or whites of the eyes (jaundice), stomach ache, and dark-coloured urine.
• Allergic reactions such as skin rash or hives.

These are not all of the possible side effects of Tigan. You should always consult your healthcare provider for medical advice about your condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Tigan, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

• Liver disease.
• Kidney disease.
• Do not administer this medication to a child or adolescent without medical supervision, especially if the child has a fever, flu symptoms, or chicken pox.
• Serious CNS adverse reactions such as coma, depression of mood, disorientation, and seizures have been reported.

• Known hypersensitivity reactions to the medication or any inactive ingredients in its formulation.
• Children who exhibit symptoms of viral infections are at risk of developing Reye's syndrome.
• Patients with liver or kidney disease should be advised to exercise caution because the medicine is metabolised by the liver and eliminated by the kidneys.

Oral Trimethobenzamide usually takes 30 minutes to an hour to take effect. Suppositories are frequently prescribed for individuals who cannot take oral drugs due to severe vomiting. These are often taken rectally, with a start of effect similar to that of the oral form.

When Tigan is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Apomorphine.
• Diphenhydramine.
• Trimethobenzamide HCL.
• CNS depressants.
• Metoclopramide.
• Opisthotonos.
• Antihistamines.

There are two dosage forms: oral 300 mg capsules and an intramuscular injection.

The oral capsules are typically taken three or four times per day.

Tigan intramuscular (IM) injection is usually given by a healthcare professional.

If you are 65 or older or have renal impairments, your dose may be adjusted.

Store at room temperature and keep out of reach of children.

Par Pharmaceuticals manufactures Tigan.

There are lower-cost generic versions available of Tigan.

It is not advised to stop taking Tigan without speaking to your healthcare provider first.

It is not known if Tigan is safe to take while pregnant. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.