Phenergan

The active ingredient in Phenergan is promethazine hydrochloride, which is an antihistamine. Additionally, it inhibits a substance known as dopamine. Promethazine relieves allergy symptoms like rash, watery eyes, and runny nose by blocking histamine. Additionally, it may be used for sedation (drowsy) and to make you feel relaxed before surgery. Promethazine works as an antiemetic to reduce nausea, vomiting, and motion sickness symptoms by blocking acetylcholine and dopamine.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Phenergan. However, the following is a synopsis of the general guidelines for the use of Phenergan:

• Your age, weight, and the condition being treated can determine the dose and how frequently you take Phenergan.
• Use the supplied dosing syringe, a specialized dose-measuring spoon, or a medicine cup to measure liquid medication. Ask your pharmacist for a dose-measuring device if you don't already have one.
• Inform your doctor if your child's weight changes while taking this medication. Children's Phenergan dosages are determined by their weight, so any changes could have an impact on your child's dosage.
• If, while taking Phenergan, your symptoms worsen or do not go away, give

The most common side effects of Phenergan include:

• Tiredness or drowsiness.
• Dizziness.
• Confusion.
• Blurred vision.
• Nervousness or anxiety.
• Dry mouth.
• Nausea or vomiting.
• Trouble sleeping.

-Uncontrollable body movements.

• Constipation.

Some individuals may experience serious side effects while using Phenergan. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Neuroleptic malignant syndrome (NMS) - confusion, sweating, a high fever, muscle stiffness, and irregular heartbeat or rhythm.
• Respiratory depression - shallow breathing and frequent pauses.
• Excessive sleepiness.
• Seizures.
• Gangrene (injection only): purple or black skin, blisters or sores that bleed, swelling, and loss of feeling.
• Allergic reaction including anaphylaxis - skin rash, hives, or swelling in the face, tongue or throat.
• Increased risk of infection - fever, chills, sore throat, or other signs of an infection.
• Liver problems - yellowing of the eyes or skin (jaundice) and darkening of urine.

These are not all of the possible side effects of Phenergan. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Phenergan, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• If you experience uncontrollable or twitchy movements of your eyes, lips, tongue, face, arms, or legs, stop taking Phenergan immediately and contact your doctor. These might be precursors to harmful side effects.
• Children under the age of two should not be given Phenergan as it can cause serious breathing problems. Take this medication as directed by your physician if you are a child of any age.
• If you have an allergy to promethazine or related medications like fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, trifluoperazine, or chlorpromazine, you should avoid taking Phenergan.
• If you suffer from asthma or another lower respiratory condition, you should avoid taking Phenergan.
• Side effects from Phenergan may affect your ability to think or react. If you must be awake and attentive while driving or performing any other activity, exercise caution.

• Avoid alcohol as it may exacerbate some of Phenergan's side effects.
• Tell your doctor if you have any of the following to ensure Phenergan is safe for you:
• Breathing conditions such as sleep apnea, asthma, or chronic obstructive pulmonary disease (COPD).
• An allergy to sulfites.
• Seizures in the past.
• A compromised immune system (depression of the bone marrow).
• Glaucoma.
• Prostate enlargement or urination issues.
• Urinary tract blockage or difficult urination, use with caution. This medicine may make these conditions worse.
• Obstruction or stomach ulcer.
• High blood pressure or heart disease.
• Liver disease.
• Tumor of the adrenal gland.
• Low blood calcium levels.

Because Promethazine is not safe for you to take, let your healthcare provider know if you have any of the following conditions or if any of the following apply to you.

• Children under the age of two.
• Coma patients.
• Addressing issues with the lower respiratory tract, like asthma.
• Phenothiazine allergy.

Within 20 minutes of taking a dose, Phenergan should begin to work. Consult your prescriber if promethazine doesn't seem to be working for you.

When Phenergan is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Lithium (Lithobid, Eskalith).
• Methscopolamine (Pamine), benztropine (Cogentin), dimenhydrinate (Dramamine), belladonna (Donnatal, and others), atropine (Atreza, Sal-Tropine), or scopolamine (Transderm-Scop).
• Blood pressure drugs, including propranolol (Inderal), guanadrel (Hylorel), and guanethidine (Ismelin).
• A blood thinner like Coumadin (Warfarin).
• Bronchodilators like tiotropium (Spiriva) or ipratropium (Atrovent).
• Drugs for the bladder or urine, including solifenacin (Vesicare), oxybutynin (Ditropan, Oxytrol), and others.
• Antidepressants such as monoamine oxidase inhibitors (MAOIs) like methylene blue injection and isocarboxazid, tricyclic antidepressants (TCAs) like amitriptyline, SSRIs like fluoxetine, and SNRIs like duloxetine.
• Medications to treat prolactinoma, a pituitary gland tumor, Parkinson's disease, or restless legs syndrome.
• Drugs like dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), mepenzolate (Cantil), or propantheline (Pro-Banthine) that treat stomach ulcers or irritable bowel syndrome.

Allergy Symptoms:

Adults and children (2+ years of age): Take 25 mg by mouth once daily at bedtime. Alternatively, take 6.25 mg to 12.5 mg by mouth up to three times daily.

Motion Sickness:

Adults: Take 25 mg by mouth twice daily. Start 30–60 minutes before traveling and repeat the dose 8–12 hours later if needed.

Children (2+ years): Take 12.5 mg to 25 mg by mouth twice daily.

Nausea and Vomiting:

Adults: Take 12.5 mg to 25 mg by mouth every 4–6 hours as needed.

Children (2+ years): The dose depends on body weight. Typically, 0.5 mg per pound of body weight by mouth every 4–6 hours as needed. A pediatrician will determine the exact dose.

"Light" Sleep Before/During a Procedure:

Adults: Take 25 mg to 50 mg by mouth once at bedtime the night before the procedure.

Children (2+ years): Take 12.5 mg to 25 mg by mouth once at bedtime the night before the procedure.

Pain Relief Before and After Surgery:

Adults:

Before surgery: Take 50 mg by mouth with other pain medications.

After surgery: Take 25 mg to 50 mg by mouth with other pain medications.

Children (2+ years):

Before surgery: Dose depends on body weight, usually 0.5 mg per pound, taken with other pain medications.

After surgery: Take 12.5 mg to 25 mg by mouth with other pain medications. A pediatrician will determine the exact dose.

Store Phenergan at room temperature and out of reach of children.

The pharmaceutical company that manufactures Phenergan is known as Sanofi.

There are several different generic versions of Phenergan available at a lower cost.

You may experience lightheadedness, sweating, nausea, a racing heart, and difficulty falling asleep if you abruptly stop taking Phenergan after taking it for a long time. Avoiding this can be achieved by gradually stopping Phenergan. It is still highly recommended to speak to your healthcare provider if you want to stop taking this medication.

Phenergan has been used to treat nausea and vomiting during pregnancy. It is typically used if other treatments do not work. Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

It is not known if Phenergan is found in breast milk. It is generally thought that the occasional short-term use of promethazine for nausea and vomiting poses little risk to the breastfed infant. However, talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.