Periactin

The active ingredient in Periactin is cyproheptadine hydrochloride. It works by blocking histamine receptors in the body, reducing allergic symptoms. It also has anticholinergic effects and blocks serotonin, another natural chemical involved in several body functions. These actions help decrease itching, skin rash, swelling, and allergic discomfort.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Periactin. However, the following is a synopsis of the general guidelines for the use of Periactin:

• Tablets should be swallowed with water.
• Do not take more than directed, especially because high doses increase the risk of drowsiness and anticholinergic effects.
• If you miss a dose, take it when you remember unless it is nearly time for your next dose. Skip the missed dose if needed. Do not double the next dose.
• Do not give Periactin to young children unless a healthcare provider says it is safe for them.
• Avoid drinking alcohol with Periactin, as it can increase drowsiness. This medication may reduce alertness and make it unsafe to drive or use machinery.
• People over 65 years of age or young children may be more sensitive to the effects of cyproheptadine.

Some mild or common side effects of Periactin seen in clinical trials as compared to placebo include:

• Drowsiness or sleepiness.
• Dry mouth or dryness in the nose and throat.
• Constipation.
• Blurred vision.
• Increased appetite or weight gain.
• Upset stomach or other gastrointestinal symptoms.

Some individuals may experience serious side effects while using Periactin. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Skin rash, hives, swelling, or signs of an allergic reaction.
• Difficulty breathing or anaphylactic shock.
• Excitement or nervousness, which sometimes occurs in young children or at high doses.
• Jaundice or yellowing of the skin or eyes may indicate hepatic problems.
• Palpitations or significant changes in blood pressure.
• Problems urinating or urinary retention, especially in people with an enlarged prostate or bladder issues.
• Severe photosensitivity or sun sensitivity.

These are not all of the possible side effects of Periactin. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Periactin, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including if you have:

• Glaucoma or increased pressure in the eye.
• Thyroid disease.
• High blood pressure or heart-related conditions.
• Liver disease or jaundice history.
• Enlarged prostate or trouble urinating.
• Asthma or breathing problems.
• Any gastrointestinal blockage.

Are allergic to cyproheptadine or any ingredient in the medication (including lactose).

Have glaucoma.

Have an enlarged prostate that causes urinary retention.

Have a blockage in the stomach or intestines.

Are taking monoamine oxidase inhibitors such as tranylcypromine.

Are a newborn or a premature infant.

Antihistamines like cyproheptadine usually begin relieving allergy symptoms within a few hours.

When Periactin is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

• Monoamine oxidase inhibitors such as tranylcypromine or other MAO inhibitors.
• Other antihistamines, sleep aids, or medicines that cause drowsiness.
• Alcohol, which increases sedation.
• Certain antidepressants and anticholinergic drugs.
• Thyroid medicines, which may interact with histamine-receptor effects.

Periactin contains 4mg of cyproheptadine hydrochloride per tablet.

Store Periactin at room temperature. Keep the bottle tightly closed and stored away from moisture. Always keep this medication out of the reach of children.

It is manufactured by Merck Sharp & Dohme.

Yes, it is available from many manufacturers of generic drugs.

Do not stop taking Periactin suddenly without advice from your healthcare provider, especially if you have been taking it regularly. If you miss a dose, take it when you remember, unless it is nearly time for the next dose. Do not double the next dose.

Safety information for the use of Periactin in pregnancy is limited.

Talk to your doctor if you are already pregnant or if you have any plans to become pregnant. They will know or recommend what is best for you.

Cyproheptadine should be used with caution during breastfeeding. Antihistamines may affect milk supply or cause effects in the infant.

Talk to your doctor if you are already breastfeeding or if you have any plans to breastfeed. They will know or recommend what is best for you.