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Buy Desogen Online
(Desogestrel/Ethinyl Estradiol)

What is Desogen?

What is Desogen?

Desogen (desogestrel and ethinyl estradiol) is a combination oral contraceptive used to prevent pregnancy. It contains two hormones: desogestrel, a progestin, and ethinyl estradiol, an estrogen. Together, they work to stop ovulation and make changes in the uterus and cervical mucus to help prevent sperm from reaching an egg.

Desogen is available only by prescription. Like other hormonal contraceptives, it does not protect against sexually transmitted diseases (STDs), including HIV.

Order Desogen online today and save!

Purchase Desogen from Universal Drugstore today and save!

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  • 0.15/0.03mg

Desogen brand

Desogen 21 Day 
0.15/0.03mg

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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Marvelon 21 Day in United Kingdom.

Desogen 28 Day 
0.15/0.03mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Marvelon 28 Day in United Kingdom.

Also available from Canada
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Desogen goes by the trade name Marvelon in Canada.
Prescription Required
Product of Canada

Product of Canada

Marketed as Marvelon 28 Day in Canada

Desogestrel/Ethinyl Estradiol 21 Day (generic Emoquette)

What are generics?

Desogestrel/Ethinyl Estradiol 
0.15/0.03mg

Prescription Required
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Prescription Required
Product of United Kingdom

Product of United Kingdom

Marketed as Rigevidon in United Kingdom.

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Important information about Desogen

The active ingredients in Desogen are desogestrel (a progestin) and ethinyl estradiol (an estrogen).

  • These hormones prevent pregnancy in several ways:
  • Stopping ovulation (the release of an egg from the ovary).
  • Thickening cervical mucus, which makes it harder for sperm to enter the uterus.

Changing the uterine lining (endometrium) makes it less likely for a fertilized egg to attach.

Together, these actions provide effective birth control when Desogen is taken correctly; one pill every day, at the same time each day, for 21 consecutive days, followed by 7 hormone-free days (or placebo pills) during which you may experience a menstrual period.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Desogen. However, the following is a synopsis of the general guidelines for the use of Desogen:

  • Take one tablet by mouth every day at the same time.
  • Start your first cycle of Desogen on the first day of your period (or as directed).
  • Use an additional method of birth control (spermicide or condom) during the first 7 days of your first pack to prevent pregnancy if you do not start it on the first day of your period.
  • If you miss a pill, follow the specific instructions provided in the package insert, as missing doses can increase the risk of pregnancy.
  • Vomiting or severe stomach pain may affect absorption.
  • Do not skip pills, even if you experience breakthrough bleeding or amenorrhea (missed periods). Consistency is key to maintaining effective oral contraceptive protection.

Some mild or common side effects of Desogen include:

  • Nausea or vomiting.
  • Breast tenderness or enlargement.
  • Headache.
  • Bloating.
  • Stomach cramps.
  • Weight gain or fluid retention.
  • Breakthrough vaginal bleeding or spotting.
  • Changes in menstrual cycles or vaginal discharge.
  • Mood changes.
  • Contact lens intolerance.

Some individuals may experience serious side effects while using Desogen. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

  • Signs of blood clots (thrombosis or thromboembolic events), such as chest pain, shortness of breath, or swelling in the legs.
  • Sudden severe headache, vision changes, or difficulty speaking (possible stroke).
  • Abdominal pain, yellowing of the skin or eyes, dark urine, persistent nausea, or loss of appetite (liver problems such as hepatitis or gallbladder disease).
  • High blood pressure (hypertension) or symptoms of a heart attack (pain radiating to the arm or jaw and chest pain).
  • Breast lumps or signs suggestive of breast cancer.
  • Severe allergic reaction, such as rash, itching, or swelling of the face or throat.

These are not all of the possible side effects of Desogen. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Desogen, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure your provider is aware if you have or have had:

  • Blood clots, thrombosis, or thromboembolic disorders.
  • Heart disease, coronary artery disease, heart attack, or stroke.
  • High blood pressure or hypertension.
  • High cholesterol or hyperlipidemia.
  • Liver disease or liver tumors, including hepatitis C or other liver problems.
  • Kidney disease.
  • Gallbladder disease.
  • Breast cancer, or a history of endometrial or cervical cancer.
  • Thyroid disorders or diabetes.
  • Unexplained vaginal bleeding.
  • Depression or mood disorders.

Boxed Warning

Smoking, while using hormonal contraceptives like Desogen, causes an increased risk of serious cardiovascular side effects, such as blood clots, stroke, and heart attack, particularly in women over 35 years of age or in heavy smokers (15 or more cigarettes/day).

Desogen should not be used if you:

  • You are pregnant or think you might be pregnant.
  • Have or have had blood clots, deep vein thrombosis, pulmonary embolism, stroke, or heart attack.
  • Have liver disease, liver cancer, or active hepatitis.
  • Have breast cancer or any cancer that is estrogen- or progestin-sensitive.
  • Have unexplained vaginal bleeding.
  • Have certain types of migraines with aura.
  • Are allergic to desogestrel, ethinyl estradiol, or any inactive ingredients in Desogen.

When started on the first day of your menstrual period, Desogen provides protection immediately. If started at another time in the cycle, use an additional method of birth control (like a condom or spermicide) for the first 7 consecutive days.

When Desogen is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

  • Antibiotics like rifampin or rifabutin.
  • Antivirals for HIV/Hepatitis C, such as ritonavir or boceprevir.
  • Antifungal medicines like griseofulvin.
  • Anticonvulsants (seizure medications) such as carbamazepine, phenytoin, or topiramate.
  • St. John’s Wort (herbal supplement).
  • Thyroid medications and some cholesterol-lowering drugs.
  • CYP3A4 inhibitors or inducers, which can change plasma concentrations of hormones in Desogen.
  • Other hormonal contraceptives or hormone replacement therapy.

Desogen is available as tablets containing 0.15 mg desogestrel and 0.03 mg ethinyl estradiol. Each pack contains 21 active pills and 7 placebo pills.

Similar brand names and formulations may include Apri, which contains the same active ingredients and strength.

Store Desogen tablets at room temperature (68°F to 77°F or 20°C to 25°C), away from moisture, heat, and direct sunlight. Keep the medication in its original blister packaging and out of reach of children and pets. Do not store in the bathroom.

Desogen is manufactured by Organon LLC, a global pharmaceutical company known for its women’s health products, including various birth control pills and hormonal contraceptives.

Yes. Generic versions of Desogen are available. Generic drugs contain the same active ingredients and have the same pharmacology, safety, and efficacy as the brand-name version but are often more affordable.

If you wish to stop taking Desogen, speak with your healthcare provider first. Stopping suddenly can lead to temporary changes in menstrual cycles, breakthrough bleeding, or amenorrhea. Discuss alternative methods of birth control to prevent unintended pregnancy if you are sexually active.

If you plan to become pregnant, your provider may recommend completing your current pill pack before stopping. Ovulation typically returns within a few weeks after discontinuation.

Desogen should not be used during pregnancy. If you become pregnant while taking Desogen, stop taking it immediately and contact your healthcare provider. q

Desogen is generally not recommended while breastfeeding, especially during the first few weeks after delivery, as it can reduce breast milk production and small amounts of hormones may pass into the milk. Talk to your healthcare provider about safer contraceptive options while breastfeeding, such as a progestin-only pill or non-hormonal methods.

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Important information about buying Desogen from UniversalDrugstore™

Once you complete your order, we process, verify, and dispatch your medication. You’ll receive email updates at each stage, including tracking details once your order ships. If any additional documentation is needed (such as a valid prescription), we’ll contact you promptly. Once approved, your order is charged and delivered directly to your doorstep.

Orders are typically processed within 1–3 business days once all required documents are received and approved. Standard delivery times range from 10–18 business days, depending on your location.

Yes! Once your medication ships, you will receive an email with tracking information so you can monitor your shipment every step of the way.

Our Customer Care team is available 24/7 to assist with any order-related concerns or questions. If you experience delays, missing items, or need support, contact us using the details provided in your confirmation email.

All orders are shipped in discreet, plain packaging to protect your privacy. Medications are securely packaged to prevent damage and ensure they arrive in top condition.

Yes. We use cold-chain shipping methods to safely transport temperature-sensitive medications, ensuring they maintain proper storage conditions throughout delivery.

Shipping costs vary depending on your location and shipping method. Free shipping promotions may be available—check the checkout page for the latest offers. Orders above $100 going to a US destination will receive free shipping.

Currently, we do not bill Medicare or Medicaid directly. However, we provide detailed receipts and documentation that you can submit to your insurance provider for potential reimbursement.

Universal Drugstore does not bill private health insurance directly, but we provide a detailed invoice that you can submit to your insurer for possible reimbursement. Many insurers will accept Universal Drugstore’s documents, but if you have any questions, check with your insurance company prior to purchasing.

We use advanced SSL encryption and secure payment processing to ensure that all transactions are 100% protected against fraud and unauthorized access.

Universal Drugstore offers many generic alternatives that provide the same active ingredients at a lower cost. Search for your medication and compare pricing for generic vs. brand-name options. Generic availability depends on the medication.

If your medication requires a prescription, you must upload it online, via email, or fax. Over-the-counter (OTC) medications do not require a prescription. All prescription medication purchases require a valid and approved prescription. The Universal Drugstore customer care team can contact your doctor directly to get your prescription, and ensure all information is up to date.

Yes! You can add multiple medications to your cart, including prescription, OTC, and pet medications, and complete your purchase in a single checkout process.

Yes! If your prescription includes refills, you can reorder quickly by logging into your account and selecting your medication for a hassle-free refill process. Always refill your medication proactively and ontime, to ensure you do not run out of important medication.

Yes! We offer:

  • Up to 80% savings on medications
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  • 10% off your first order for new customers

We offer 24/7 customer support via phone, email, and chat. Visit our Contact Us page for assistance with ordering, shipping, or medication questions.

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes to increase health awareness only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. 



Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.